🧵 View Thread
🧵 Thread (49 tweets)
oh this is good a more-likely cause of divide in use of embryo selection than simple wealth: different rates of planned vs unplanned pregnancy across populations oh boy https://t.co/BXUidfZjCF
@eigenrobot So basically same thing we have going on now. People will be taking risks w/ their offspring & not accounting for how diet and environment affect epigenetic processes, mostly because all our science is tainted by statistical artifacts stemming from RCTs and street light effects.
@eigenrobot Meanwhile, someone has stolen my ideas is using it to build super soldiers.https://t.co/BqvaEQiPGG
@eigenrobot The kind of person who is willing to eat dog shit despite social taboos.https://t.co/dKmwhNrYcx
@eigenrobot What's funny to me is I score in the upper red zone and am autistic. I was natural born, but it's funny to think that you may be inadvertently selecting for autistic children given this meta-analysis of autism risk in IVF:https://t.co/0NwWetJMx7https://t.co/9v5OqPbZec
@eigenrobot Once you get past the hurdle into IVF, you're already high risk of failed IVF and may need to do the harder ones that increase the risk.https://t.co/cvKn32NnKn
@eigenrobot Did you know autistic people are more likely to infertile?Its really funny to me. Makes me laugh.https://t.co/LfpyLGf8dZ
My GF's endocrinologist looked at her blood work, seeing fixed Testoterone, fixed hba1c, fixed TSH, and improved vitamin D.... And just assumed it was from exercising & losing weight.She's exercised less and weight loss occurred AFTER her PCOS fixed.https://t.co/HpMRJN2rxO
@eigenrobot I can quote the CDC on this too."Overall, children conceived using ART were about two times more likely to be diagnosed with ASD compared to children conceived without using ART." https://t.co/FKOiXSoAEj
@eigenrobot Is autism genetic? Can we select for autism in the embryo? If so, do we want more autistic people?https://t.co/ghJEszjeXY
@ekverstania It's as if this view autism as entirely genetic and thus view it thru a genetic essentialism lens. Effectively these views are reinforcing the idea of an autistic master race / racial minority group. Which turns this discussion into one about identity.https://t.co/eO3EHIwnly
@eigenrobot I don't like being autistic. https://t.co/evlPiEo4eP
@eigenrobot The funny thing is, this will inevitably lead to generations of depressed high-IQ autistic people who end up not having children. So the problem is self-mediating. Doesn't take a genius to figure this out.https://t.co/jCislSzsqJ
@eigenrobot What happens if you also select for gut health tho...https://t.co/1O3wPXoYdx
@eigenrobot Selecting for IQ alone is not going to lead to healthy people. https://t.co/VHTGg8LVdJ
@eigenrobot Did you know if you wanna score really high on an IQ test used for egg / sperm selection, you can just dope yourself with moda?Why select among your own egg/ sperm when you can select among everyone's?https://t.co/3m7Ru4AeBI
@substitute @eigenrobot I dug into that whole IQ + reaction time thing that rely on the fact that olympic sprinters have high IQs. Turned out many are doping with stuff like modafinil. The more I dig, the more fall apart. I think it's a deep myth.I wonder why so many football players get arthritis.
@eigenrobot This isn't really even a new idea. https://t.co/WKXdgjSAzU
@eigenrobot "When it comes to physiological diseases, people with high cognitive abilities are 213% more likely to have environmental allergies, 108% more likely to have asthma, and 84% more likely to have an autoimmune disease."https://t.co/83GoYEqBYa
@eigenrobot "available evidence suggests that gut microbiota is linked to cognitive performance and that manipulation of gut microbiota could be a promising avenue for enhancing cognition which warrants further research." https://t.co/We9IRLnH5Fhttps://t.co/MvM5zcA1ds
I figured out how to reverse a life long Prosopagnosia because I wanted to be able to recognize faces of famous scientists do speed up my ability to link ideas together.https://t.co/tw6FpbjW6wI am am not smart enough to explain how dumb we are all collectively being right now.
@eigenrobot Fix the gut."In summary, the present study showed the differences in the abundance of gut microbiota between fertile and infertile female groups, [...] supplementation helped improve gut dysbiosis and the success of pregnancy in females with infertility" https://t.co/F6ob6RR6I9
@eigenrobot Did you know the Stroop test correlates really well with IQ? I can literally get perfect scores now.https://t.co/3OJ7x9K2WR
@eigenrobot I can destroy IQ tests now. They're jokes.https://t.co/wA0i7eExl2
@eigenrobot Skeletal muscle strength, reaction time, memory, cognitive flexibility and balance, all thru the roof now. I am going to try to take another formal IQ test this summer to see how well I do.https://t.co/wYfh7w4fff
@MimeticValue My favorite games involve reaction time. Some days I have sub 5ms responses, other days I'll have 50+ms responses. I IQ tested as part of autism diagnosis. I scored high despite it being a bad day for me mentally. There is a major gap in reasearch IMHO https://t.co/VQBQmXlrRK
@eigenrobot We haven't even begun to explore this space in any meaningful capacity, and everyone is still stuck on an idea that IQ is innate cuz of our collective idiocy.https://t.co/57BIvC5cNG
@pmarca @sbaroncohen When I took an IQ test to get my autism diagnosis, I was in the middle of an M.S. decline. I still technically qualified for Mensa.IQ drops are really common with that condition. Do you ever wonder if you can raise IQ with gut bacteria? Cuz you can. https://t.co/wYfh7w4fff
@eigenrobot "Myelin degeneration and diminished myelin renewal contribute to age-related deficits in memory" [2020]https://t.co/wraVHaMjoPI linked this to autism in 2019, lmao.https://t.co/27Hng1KQVd
@eigenrobot I already fixed this back in Jan 2022:"Memory impairment in autism goes beyond poor facial recognition, a Stanford Medicine team showed. The finding suggests a wide role for memory in the neurobiology of the disorder." [2023] https://t.co/Ou0cgWAVlO
@eigenrobot The research on gut health and memory problems has been stewing since 2018, when they were exploring lactobacteriahttps://t.co/Pe2grUbbA5I was already in full swing on this by 2019https://t.co/cfA28sCWDo
@SimnaniIqbals @Mangan150 @SumSumFliege There are a bunch of high IQ genes tied to Longevity. Some of the correlations may be due to changes in insulin management and downstream impacts on cholesterol/calcium absorption in the gut. Memory and mental ability may enhance this further thru smarter diet choices.
@eigenrobot We can fix the demyelination by fixing the bile function, and you can do that via gut health.https://t.co/CrgG7OQe0t
@PLT_cheater @The_Lagrangian @JimmyRis yes, good thing my liver can produce bile acid on demand on top of having a well functioning gallbladder. I specifically taylor my diet to promote Lactobacilli colonies (what ferments saurkraut?) that trigger FXR antagonism to increase bile acid pool size https://t.co/GsosCWhdpg
@eigenrobot There's been a hypothesis about brain myelination and intelligence on record since 1994. I know a lot about Einstein's brain, you see... https://t.co/jOPhotlJSehttps://t.co/fdaQ6J1g0h https://t.co/jpmcLDgTFt
@eigenrobot ANYWAY... you can actually calculate how much it costs to select 1000 embryos. at anywhere from 8-15 per harvest it isn't that bad. $10k-$20k a harvest. The hard part is that you have to account for the storage costs and time between procedures to heal. https://t.co/3Xn1HnJ6aC
@eigenrobot Most people don't wait that long after harvesting because they want a child right away; so typically its an average of two harvests before implantation. Most of the time involved is the fertilization step which also doubles as a test of the egg validity. https://t.co/pPC1rVymSt
@eigenrobot Guessing if an egg is valid with out actually throwing sperm at it is much harder. I have been exploring this space because it may also help us with artificial oocyte generation.Testing eggs without killing them is hard.https://t.co/ZmYoO1ceHg
"While at the organismal level, biological aging can be estimated by telomere length and DNA methylation signatures, reliable biomarkers that can predict reproductive age are much needed to gauge the quality of an oocyte." https://t.co/xSn9IZWWJm🥚👀https://t.co/6jpFZislXv
@eigenrobot You an get a an estimate by comparing genes, but this isn't the same thing as testing the individual egg or sperm. Companies exist that can do the former.https://t.co/F3JFU6eNwf
@eigenrobot The cost to do an IVF with "Preimplantation Genetic Testing" is significantly more than just a simple IVF. Typically that is done just to test for issues that impact implantation. I can't find prices on additional screening costs.https://t.co/VsR9jsshWX
@eigenrobot Eyeballing it, this would cost a minimum of $2,000,000 assuming the $20k price is roughly accurate.It may also be dangerous to do repeatedly since the process of harvesting is stressful. And the meds associated aren't part of the procedure cost.https://t.co/UwDAE7gK5u https://t.co/R2UZ1muYV2
@eigenrobot This sounds like a lot, but considering you can buy a gallon of hose cum for 4.7 million from @GLOCKInc for a pure bred racehorce, the prices make more sense.I'm still trying to find prices on dog semen.https://t.co/axRh86bb7B
@eigenrobot If really rich people will pay that much for horse cum, then I can imagine that this is already being done in some circles.https://t.co/Xid06uI6ed
@eigenrobot Interestingly, the pre-implant test for horse embryos only cost $120https://t.co/7PY368Ce7xKnow any good vets?
@eigenrobot You can... just not tell anyone you're growing vat babies.https://t.co/4PPO8QfwEqhttps://t.co/4cu93PahES https://t.co/Gjdq19ccA9
I nightmare of futures in which external pregnancy (ectogenisis) is required by law in order to minimize a child's chances of mental disorder; of course that mental disorder is defined by the state.In secret, the military uses that technology to raise clone armies in vats.
@eigenrobot Something that stood out to me in my research is that someone has successfully freeze-dried mouse cum and mailed it thru the post successfully.https://t.co/oKCDQbEgu6
@eigenrobot If you haven't yet, watch "man of steel" (2013), I don't want to give away the plot, but it's a good sci-fi movie on the topic of ectogenesis. Superman has an autistic sensory meltdown in it too, lmao.https://t.co/HMdGN6oJWF
@eigenrobot Human monkey hybrids, grown in vats. Served up in the next clone war. I think 2040 is a better estimate.https://t.co/rL3TCHLnvQ
@eigenrobot Tired: Nietzsche ÜbermenschWired: Jung's Al-chemical Self TransformationInspired: Svyatagor’s BiocosmismHired: Embodying the absurdity of the universe and naming my squirrelfriend Camus so he can hunt dogs. https://t.co/5LrHyLviV9https://t.co/cLWO2LNYbk
@eigenrobot One of the reasons why I fixate on grip strength isn't because of IQ, but because heart muscle failure seems to correlate it and is likely a cause for heart attacks s we age. https://t.co/V93uLMPuVRAutistics get sarcopenia at really high rates. https://t.co/HiZRQ2Wxhf
@eigenrobot Heart attack risk is also very high. I make funny poetry about this. https://t.co/YQWFkXNN9b
I know I'm autistic b/c of obsesses.And things that I say like "Do you think my semen fluoresces?"Autism has weird chemistry around choline.TMAO, ayy-lamo, I'm sure this is fine.I wonder if it matters for phosphocreatine.Cuz on solving my heartattack risk? I'm pretty keen.