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If FMTs can treat Multiple Sclerosis and Bipolar...Why not schizophrenia?> " The molecular components of the axo-myelin unit could be important targets for novel therapeutic approaches to schizophrenia and bipolar disorder."https://t.co/8kB61d8DDc
> " classical clinical-neuropathological correlations have established that disruption in myelination can produce a high fidelity phenocopy of psychosis similar to [schiz], the role of dysmyelination in schizophrenia remains controversial." [2015] https://t.co/B0R1hxikuM
"Several recent gene expression studies have found abnormal expression of genes involved in myelination in the prefrontal cortex of brains from patients with schizophrenia and other psychiatric illnesses." [2009] https://t.co/omoLM7Whzv
"These findings support the notion that disruptions in myelination may contribute to the cognitive and behavioral impairments experienced in schizophrenia, although further evidence of causation is needed." [2024] https://t.co/v64Vvm6eTA
"These findings implicate oligodendrocyte and myelin dysfunction as a primary change in schizophrenia, not only as secondary consequences of the illness or treatment. [...] therapeutic opportunities for patients suffering from schizophrenia." [2013] https://t.co/RG72LYLkCg
"The genetic linkage results seem to be replicated in some cases but in others are not. From these results, we cannot draw a fine map to a single locus or gene, leading to the conclusion that schizophrenia is not caused by a single factor/gene." [2008] https://t.co/le05gBCRHF
inb4 hnRNP gene expression is is modulated by gut health"compaction and stability of myelin, as well as modulating the sphingolipid signaling pathway, endocannabinoid signaling, synaptic vesicle cycle, and GABAergic synapses," [January 2025]https://t.co/pDWZH7LUvd
> "Our results demonstrate that hnRNP I is an evolutionarily conserved Notch inhibitor and plays an essential role in intestinal homeostasis."https://t.co/JK5Vw5f3xh
Notching signaling perterbations, in my autistic+schizophrenic ass?More likely than you think.https://t.co/qxq9PoRoyK https://t.co/ucVy7j7Wgm
Keep looking for genes to turn off or drugs you can dump in to cure a disorder that is actually just gut health problems driven my westerner's gut health being so fucked.https://t.co/fUXgWmQttV
@Bonecondor I traced this to problematic microglia gene *expression* that has been implicated in a bunch of brain disorders, not just autism, but also alzheimer's and parkinson's.Basically I modulate how M0 differentiate into M1 or M2 and calmed down immune system.https://t.co/onhLcE7Le8
I posted this on april first, but it is the gene pilled bio/acc idiots who ae all fools.https://t.co/p43AgtCqW3
Someone please tell the pope he is illegitimate.https://t.co/jJ4RZtQB8U
Who's going to win? Some autistic guy who DGAF so is out here making jokes about sonic hedgehog to reference a children's cartoon about evolution and gene splicing, or some curmudgeon who like to bash religion because it gives him high status?Jawsome.https://t.co/s8oerEBV7S https://t.co/cefZkXGI0c
Is this legit?https://t.co/Sj70UxiQNe
@market_death Gosh I want some random autistic like me to drop in and tell me when the pope become corrupted and tell me about the history of Catholicism's split with the orthodoxy and the church of crete. "Someone should tell the pope he's illegitimate." https://t.co/uAZwAnEceS
Listen, its not like I spent the last 10 years of my life trying to (and successfully, I might add) fix a degenerative brain disorder tied to these pathways or anything. /shttps://t.co/ATY52eRGn0
@IterIntellectus A commonality in autism, multiple sclerosis, and other neurodegenerative disorders is a different kind of dysregulation of SHH related pathways tied growth. The gut microbiota–oligodendrocyte axis may be teh root cause of all of this! https://t.co/74lph8vA1k
Please, stop being dumb. I'm the hashtag actuallyautistic retarded one, what's you're excuse?https://t.co/n82eoWP6ws
Freud can go fuck his mom. Then maybe his repressed desires that he summoned thru literal cocaine and automatic writing wouldn't be so full of shit.https://t.co/g3yWRitiuX
We've been poisoning ourselves for 120+ years and blaiming it on mental demons and spooks, or looking for genetics.Gut bacteria and diet are inherited and passed along family lines too, idiot!https://t.co/8JPrfiIEMC
@jayjoseph22 I think its funny that so many of the GWAS studies on autism have drawn mostly blanks and have moved on to 'random mutations' as a proximate cause. https://t.co/AScXdo4azVThis is what sent me down the path of DNA repair mechanism being disrupted.
Yeah, that's right, i'm gonna use the R-word. > "Our results thus demonstrated that the gut microbiome might modify the transcriptomic profile in the brain" [2024]https://t.co/cPmPY1VrE7Get fucking rekt, nerd.
Gut bacteria induced shifts in the brain's immune cell gene expression a demylination adjacent disorder, that everyone is assuming is genetic because they have heir heads so far up their ass that they can't even smell their own farts?https://t.co/g2UQR8hgV8
What if schizophrenia isn't real? What if its just a random and arbitrary diagnostic label for a set of behaviors stemming from an autoimmune disease state driven by gut health disrupting dopamine/serotonin and gaba/glutamate signaling?https://t.co/qIBlryhrDP
It's funny cuz this line of thinking implies that schizophrenia is literally a collective hallucination. https://t.co/5siWgP61N7
@KetoCarnivore @SteakBased @fancypirate8 @Mangan150 Keto helps Diabetes Type II. Diabetes Type II is a risk factor in schizophrenia and autism in children. I suspect immune regulation influence on brain, particular fear memory pathways (e.g. causal 'state dependent learning'?). It's wild what that uncovers: https://t.co/0Jot0zvfjI
We just made it up back in the late 1890s and then slowly peeled away other diagnostic labels as we flailed around trying to attribute it to mental demons & trauma.https://t.co/5GkvDuP0Tu
@worlddestroyar @Metabolic_Mind Fun fact: this implies that the reduction in schizophrenia symptoms that shows up in Keto research (as well as responding well to niacin) could also be impacted by gut health. We need to take a hard look at this space.https://t.co/Qi24ZQbye0
It's literally that simple. we're all just fucking dumb, clinging on to our closely held narrative about the human condition. A nation that is Nietzsche and Freud pilled to the point on neurosis. https://t.co/cxidI0UQY2
@simonsarris @dvassallo What @GRITCULT is describing is Nietzsche's "Rausch".Guy went int the woods and ate better, suddenly felt alive again. Fool decided this was the human condition and now the entire western world repeats it.Eat shit Nietzsche https://t.co/zQzJs5D4iP
You must understand how foolish you look, talking about gene selection of children when your guts are so fucked up you can't even think straight."The microbiome-driven impact of western diet in the development of noncommunicable chronic disorders" [2024]https://t.co/JJcPAhRmik
But much of the damage had already been done.https://t.co/E2NJRZzUuy
Do you ever wonder if treatment resistant schizophrenia is actually autism?Or what if the reason why the meds weren't working was because this is all mediated thru gut microbiota metabolism factors and this assumption is wrong? https://t.co/6fOkkY1Pij https://t.co/pBHVGpPhSY
