Community Archive

🧵 View Thread

🧵 Thread (41 tweets)

Placeholder
UltimApe@ultimapeabout 1 year ago

If you make fun of me, realize you're talking about someone who was litterally crawling on the floor and shitting himself 3 years ago after suffering from multiple sclerosis symptoms for 12 years and a diet of someone in abject poverty. https://t.co/XDMFmAb5H7

Placeholder
Bryan Johnson@bryan_johnsonabout 1 year ago

Ppl dunk on me by comparing me to some of the most beautiful people in the world. It's all good and I welcome it. Here is the context they may not have: 1. I had poor health habits for the first 43 years of my life, including grinding as an entrepreneur for 20 years and 10 years of chronic depression. This caused a lot of aging damage in me. 2. I was never taught basic self care around sleep, diet or exercise. In fact, I was taught the opposite: that I wasn't working hard enough if I wasn't sacrificing my health. This resulted in my health being very bad. 3. Yet despite this, three years into developing my health protocol, my health biomarkers are perhaps best in world. Top 1% in slowing my speed of aging, cardiovascular ability, bone health, sleep, inflammation, etc. That's a stunning turnaround that should give everyone hope. I've open sourced it all for everyone's benefit. 4. Some people are genetically gifted; have maintained good health practices their whole life; have always focused on their aesthetics. Good for them and they're lucky to have people in their life who encouraged this. 5. My message is for people to prioritize sleep, maintain a healthy diet, exercise daily and to stop unhealthy behaviors. This makes people feel uncomfortable because it challenges their world view that self-destructive behaviors are "living life" and virtuous. They're also addicted to this slow boil suicide and can't stop. I understand, I've been there. Instead of introspection though and in order to soothe themselves, they try to discredit health endeavors being a worthy pursuit. One of the empowering mental models for everyone is focusing on earning the respect of those who exist in the 25th century. A read of history will show that in any time and place, 99.9% of those alive lived in accordance to ideas of dead people. They're living in the past. The future is always present. It's only a question of who can see it. This is the moment that we dare ask the unthinkable, will we be the first generation to not die? Only a small number of us need to believe this to flip the zeitgeist. Then, once it's the norm, others will do it because that's what everyone else is doing.

7.7K 365
37 3
10/9/2024
Placeholder
UltimApe@ultimapeabout 1 year ago
Replying to @ultimape

I welcome it. I spent $170 on dog shit pills to fix my health. My life a divine comedy.Make fun of me. I'm fucking crazy.

15 3
10/9/2024
Placeholder
UltimApe@ultimapeabout 1 year ago
Replying to @ultimape

My message? Fix your gut.

18 0
10/9/2024
Placeholder
UltimApe@ultimapeabout 1 year ago
Replying to @ultimape

I literally have a stronger grip than this guy at 63kgs, and 3 years ago it was 27kgs.And you know what i'm doing? I'm gonna eat Gorilla biscuits.https://t.co/Aejgbu0C8o

Placeholder
Bryan Johnson@bryan_johnsonalmost 3 years ago

My results: + Grip strength (dominant/non): 60/54kgs, age 33/43, LPS + Push-ups: 47, age 18, LPS + Curl-ups: 75 (max for test), age 45, LPS + Sit & Reach: 27", age 18, LPS Each w/clinical grade guidelines + precise adherence LPS = lowest possible score https://t.co/FQmT9qmB9n

67 2
6 1
10/9/2024
Placeholder
UltimApe@ultimapeabout 1 year ago
Replying to @ultimape

I've never been able to do pushups in my life.I just 5 again. The last time I could do 5 was when I was actively training when I was 17... and it took over a year.I literally don't exercise. I sit in front of the computer and shitpost all day. https://t.co/sekSV1ploK

Placeholder
UltimApe@ultimapeover 10 years ago

@troutgirl At my best form, I could run for 10 miles and had a crazy resting heartrate. Still couldn't do more than 5 pushups.

0 1
8 0
10/9/2024
Placeholder
UltimApe@ultimapeabout 1 year ago
Replying to @ultimape

I'm 37 years old and eating literal dog feces 3 years ago has enabled me to literally be stronger and more fit than I've ever been in my life.Fix. your. gut.

16 0
10/9/2024
Placeholder
UltimApe@ultimapeabout 1 year ago
Replying to @ultimape

I have near perfect balance now. 3 years ago I could bearly stand without holding on to a wall. https://t.co/N8ynJYsfHu

Placeholder
Bryan Johnson@bryan_johnsonalmost 3 years ago

6/This speed of aging algorithm is correlated to multiple quality of life measures including grip strength, balance, walking speed, motor coordination, lack of physical limitations, perceptual reasoning, IQ, mental processing speed, self-rated health and… https://t.co/UZEZFeyIww

Quoted tweet image 1
12 1
5 0
10/9/2024
Placeholder
UltimApe@ultimapeabout 1 year ago
Replying to @ultimape

I think I could easily walk 40 miles no problem. Fast too. I have no problems with endurance and haven't been able to tire myself walking. Even when I did this when I was ~20 I was tired and it took 3 days of recovery. https://t.co/UCjx1JGzLB

Placeholder
UltimApe@ultimapealmost 5 years ago

I once walked nearly as far as a typical brown bear in a day (~10 hr). This feels like so far away right now. I can't even walk up hill to the dumpster ~200ft away.I did it once, I can do it again.This map gives me hope: https://t.co/HHdMoyS0kI

Quoted tweet image 1
21 1
3 1
10/9/2024
Placeholder
UltimApe@ultimapeabout 1 year ago
Replying to @ultimape

I used to struggle to get out of bed and was literally unable to stand without using support. Now I can lift my entire body up from sitting using only one leg.Fix your gut.

9 0
10/9/2024
Placeholder
UltimApe@ultimapeabout 1 year ago
Replying to @ultimape

I'm on pace to become the strongest person in the world in a short amount of time. I could lift an equivalent to a Amlóði: 23 kg (51 lb) in less than a year. I'm stronger now. https://t.co/MoZAJIugqk

Placeholder
UltimApe@ultimapeabout 3 years ago

@TweetAxxount1 @nosilverv @0x49fa98 I'm officially "Amlóði", which considering I couldn't lift my 10 lb weight this time last year, I'm happy with the progress https://t.co/KLrj6tNxPS

2 2
5 0
10/9/2024
Placeholder
UltimApe@ultimapeabout 1 year ago
Replying to @ultimape

I literally threw (*shot put style*) the 50lb log into the woods with one hand a few days ago. That means I can lift, carry, and throw 50lbs... in one hand.It's hard, but I can do it now.https://t.co/TtbfP89m9G

Placeholder
UltimApe@ultimapeover 1 year ago

@nosilverv @0x49fa98 It seems based on the weight of the log, I could lift a Amlóði over my head, but can't yet get a Hálfdrættingur https://t.co/nmzrWxRXVBI'm still waiting for it to dry a bit more before I go to cut it into a dumbbell.https://t.co/2YJ7WMK9QC

0 1
4 0
10/9/2024
Placeholder
UltimApe@ultimapeabout 1 year ago
Replying to @ultimape

My resting heart rate is on the level that you'd expect from elite athletes.Something profound is happening to my body. I literally can't afford olive oil nor chocolate like before, and the Gorrilla chow was basically my entire food budget. https://t.co/XR0yYCuBeB

Placeholder
UltimApe@ultimapeabout 1 year ago

@naval @bulletproofexec If I don't drink some kind of caffine in the morning, my resting heart rate stays lower that 60bpm now. I can show it with my Garmin even.Am I an elite athlete?It used to be 80-110. I don't exercise https://t.co/uRiTUb0K9A https://t.co/9bFNhY1oJL

Quoted tweet image 1
1 2
4 0
10/9/2024
Placeholder
UltimApe@ultimapeabout 1 year ago
Replying to @ultimape

Said a couple of months ago how I was gonna get my resting heart rate down to rival Bryan... and I was able to make progress doing this in the past few days.It'd have done it by now, but my dad literally had a stroke. Been kinda stressed out, y'know?https://t.co/S63JyayEPk https://t.co/oJpYq8ROH9

Tweet image 1
Placeholder
UltimApe@ultimapeabout 1 year ago

@naval @bulletproofexec I am literally outperforming @bryan_johnson grip strength and my next target is to get my resting heart rate below 40bpm.https://t.co/TWRi9b3yB9

0 1
4 0
10/9/2024
Placeholder
UltimApe@ultimapeabout 1 year ago
Replying to @ultimape

Wanna know how I'm getting it down? Litterally drinking Yagermeister and Kefir to impact my body's SCFAs so I can harbor more Butyrate production.https://t.co/DDFEtFZB3C

Placeholder
UltimApe@ultimapeabout 1 year ago

I've been experimenting lately to see if I can harbor acetate making microbes in my gut. Neutralizing small amounts of alcohol & turning it into acetate & eventually butryate should super-power my gut health. Butryate producers need lactate as well. https://t.co/cNUkQscgWg

29 6
10 1
10/9/2024
Placeholder
UltimApe@ultimapeabout 1 year ago
Replying to @ultimape

Fix. Your. Gut.https://t.co/c1IiaxjCVm

Placeholder
UltimApe@ultimapeabout 1 year ago

@bryan_johnson Butyrate is messed up with bad sleep! Fix that.> "study revealed that [sleep deprivation] and [sleep restriction] downregulated butyrate production, further causing intestinal homeostasis dysfunction via the HDAC3–p-GSK-3β–β-catenin–Nrf2–NF-κB pathway" https://t.co/A4n1NJhuB9 https://t.co/EXDsKpTnyD

Quoted tweet image 1
4 1
4 0
10/9/2024
Placeholder
UltimApe@ultimapeabout 1 year ago
Replying to @ultimape

One of the wildest outcomes from my FMT is scars are going away, and I seemed to stop burning in the sun. I was basically photophobic before my FMT and struggled to be in the sun for more than 20 minutes.https://t.co/CeTcrQdgsj

Placeholder
Bryan Johnson@bryan_johnsonabout 1 year ago

Until I was 40, I kind of destroyed my skin. Sunburns, poor diet, no skincare routine... Now I'm paying the price. Here's what I'm doing now and what I wish I'd known earlier in life... 🧵 https://t.co/NHryInqJB9

Quoted tweet image 1
4.5K 339
5 1
10/9/2024
Placeholder
UltimApe@ultimapeabout 1 year ago
Replying to @ultimape

It was super annoying because I really wanted to test if my friend's THC balm would heal sunburn. It took me months of planning and mindfulness about my diet to even begin to burn, and even then it wasn't really that bad. https://t.co/Cw5TJ5sBkO

Placeholder
UltimApe@ultimapeover 1 year ago

@DrJackKruse @Grimhood I spent months avoiding key foods to increase the chance of my skin burning under the sun. I finally got a sunburn on the solstice by sitting in the sun for an hour.Experimenting with a low dose THC cream this time.https://t.co/njNDYEz2ZJhttps://t.co/3EBy4cqVBx

0 1
2 0
10/9/2024
Placeholder
UltimApe@ultimapeabout 1 year ago
Replying to @ultimape

I have a thread about how I manged to have willful control over my internal monologue. I can turn it off and on now thru meditative triggers. I can enter flow states at will! https://t.co/LX6IcuAtVz

Placeholder
UltimApe@ultimapeover 1 year ago

I figured this out in 2021, and ultimately fixed it with an FMT in January 2022.Papers in 2023 say we have no idea what is going on here but highlight the same thing. IBD causing liver problems drives M.S. in some people?https://t.co/UQO66gRfAthttps://t.co/146l0PLIWP https://t.co/ViAnMECoSE

Quoted tweet image 1
15 2
4 0
10/9/2024
Placeholder
UltimApe@ultimapeabout 1 year ago
Replying to @ultimape

I'm not trying to live forever, i'm trying to become a demigod.https://t.co/5j8ckfJmlD

Placeholder
UltimApe@ultimapeabout 3 years ago

@andrewsyc @naval I have full access to all my memories. In fact I seemed to have reversed a life-long inability to remember names and faces. I also can remember entire songs and fixed my sense of time. I also have 5 sense synesthesia again like childhood https://t.co/9XSVeVvpzl

1 1
3 0
10/9/2024
Placeholder
UltimApe@ultimapeabout 1 year ago
Replying to @ultimape

I got that dawg in me.https://t.co/mqASskJ6Rk

Placeholder
UltimApe@ultimapeover 1 year ago

@visakanv Not sure if I shared this with you, but I got help with an AI to write a longform of my findings as an essay.https://t.co/sHX4NT2DVf

9 1
3 0
10/9/2024
Placeholder
UltimApe@ultimapeabout 1 year ago
Replying to @ultimape

Bark woof bark.Fix your gut.https://t.co/DbHmfAV9vg

Placeholder
UltimApe@ultimapeover 1 year ago

I have been hoping to work w/ medical researchers to try and get proper safety trials done before releasing the process to the public for review.But I believe in explaining how seriously I took this process I can dissuade people from doing it themselves.https://t.co/rqYR6tcvjF

16 3
5 0
10/9/2024
Placeholder
UltimApe@ultimape12 months ago
Replying to @ultimape

I have no idea what I'm dong. 🐶https://t.co/mxWTpV9FGE

Placeholder
UltimApe@ultimape12 months ago

This was Bryan's score. 135.6 lbs.I'm getting 140s regularly now :3https://t.co/X6E6WvohqD https://t.co/pCe5Xj04nX

Quoted tweet image 1
7 1
2 1
11/5/2024
Placeholder
UltimApe@ultimape12 months ago
Replying to @ultimape

Going thru the physical tests that both Bryan and Magnus went thru and I was able to do nearly all of them better than Bryan. In fact I score higher on sit-to-stand, blaance, and grip.https://t.co/xDCnon2lTh

2 1
11/5/2024
Placeholder
UltimApe@ultimape12 months ago
Replying to @ultimape

Still can't do many pushups tho. I chock that up to TRPM8 impacting testosterone's effect on upper body strength.

1 0
11/5/2024
Placeholder
UltimApe@ultimape12 months ago
Replying to @ultimape

Half of the impacts people get from exercise and balance training is improved blood flow to the cerebellum working to reverse age related decline https://t.co/LFDdKmAUo8https://t.co/KDiElh3RIB

Placeholder
UltimApe@ultimapeover 1 year ago

@thiagovscoelho @kryptoklob @eigenrobot @Race__Realist @zeta_globin @bennettpoasting Did you know that balance is tied to IQ?I selected for balance. I did not train it tho.https://t.co/rD0mOSuE53https://t.co/vMi0eWSHih

2 1
3 0
11/5/2024
Placeholder
UltimApe@ultimape12 months ago
Replying to @ultimape

You can do this thru other means.All teh autism associated balance, walking gait issues, and troubled eye movement? Cerebellar function.https://t.co/JCvAzbJJEi

Placeholder
UltimApe@ultimapeover 3 years ago

I have a strong feeling that a lot of sensory problems that show up in autism are related to the cerebellum's function. This showed up on my radar back in 2018 and fit my thinking in this space. https://t.co/FBcrosHmaR

5 1
1 1
11/5/2024
Placeholder
UltimApe@ultimape12 months ago
Replying to @ultimape

Even things like my typos that I get. Half of it is because my ability to control my hands is still slightly impaired, I am no where near as bad.Coincides with me no longer stuttering!https://t.co/VGFKh8nv11

0 0
11/5/2024
Placeholder
UltimApe@ultimape12 months ago
Replying to @ultimape

"Many of the pathological findings in MS cerebellum are shared with other neurological conditions affecting the cerebellum (e.g., neurofilament changes; Purkinje cell injury)."https://t.co/gIdfhdu8gIhttps://t.co/bGNPD4RzXT

Placeholder
UltimApe@ultimapeover 1 year ago

@AlexTheChemist @whatifalthist Walking / movement in general seems to do a whole lot. But one of them is boost anandamide."Bidirectional Association between Physical Activity and Dopamine Across Adulthood—A Systematic Review"https://t.co/clYKT9saG0https://t.co/oflzx47ht4

1 1
0 0
11/5/2024
Placeholder
UltimApe@ultimape12 months ago
Replying to @ultimape

"lol, get purkinje'd."https://t.co/BJmJwtk2Ec

Placeholder
UltimApe@ultimapeover 3 years ago

Trying to regulate mTOR via gut bacteria & immune homeostasis working in tandem to manage glucose regulation is what I think I ending up doing."Hyperactivation of mTORC1 disrupts cellular homeostasis in cerebellar Purkinje cells"https://t.co/hP6wOiBnlIhttps://t.co/ypiKm3ffDn

1 1
0 0
11/5/2024
Placeholder
UltimApe@ultimape12 months ago
Replying to @ultimape

Don't mind me, just curing things that we don't even have good brain organoid models for.https://t.co/TSOjnCYgzM

Placeholder
Cell Stem Cell@CellStemCellabout 1 year ago

Human cerebellar organoids with functional Purkinje cells https://t.co/iotEIG5sZh @AlexanderAtami1 at @USCStemCell and colleagues Neuroscience models collection highlight from @CellStemCell https://t.co/wSLheznCny

Quoted tweet image 1
17 3
1 1
11/5/2024
Placeholder
UltimApe@ultimape12 months ago
Replying to @ultimape

I showed you (sonic hedge)hog, please respond.https://t.co/4cDn3ZoAqC

Placeholder
UltimApe@ultimapeabout 4 years ago

It's really interesting how much gender seems to predispose Purkinje cell loss in mice, and how the Cerebellum physiology is one of the areas in the brain that seem to reflect gender expression.Could it be immune active steroids impact sonic hedgehog?https://t.co/syVVW5Nesz https://t.co/7DPrc5BdEu

Quoted tweet image 1
Quoted tweet image 2
0 1
1 1
11/5/2024
Placeholder
UltimApe@ultimape12 months ago
Replying to @ultimape

Sonic hedgehog cause my autism, so in making that work better, I can now run fast because of improvements in skeletal muscle tone and balance.https://t.co/19lgYpWN40

Placeholder
UltimApe@ultimapeabout 4 years ago

Premature infants have much higher risk of developing autism.https://t.co/0ZWR0CNbWMPremature infants have distinct changes in gut microbiota.https://t.co/0t70LUAE2uPremature infants have distinct changes in cerebellumhttps://t.co/91WWqi1Hs2What could be going on here?🤪 https://t.co/ycz068ERQr

Quoted tweet image 1
2 1
1 0
11/5/2024
Placeholder
UltimApe@ultimape12 months ago
Replying to @ultimape

"Why Does Running Faster Speed Up Learning in the Cerebellum?" https://t.co/olHeAey9NZ> mossy fibers

4 0
11/5/2024
Placeholder
UltimApe@ultimape12 months ago
Replying to @ultimape

It's all mTOR you see. This is what my gut shift was targeting! > Mossy fiber sprouting represents synaptic reorganizationhttps://t.co/M2FCRbMFaLUsing dog shit to fix symptoms of autism... https://t.co/gNnC5NSO5m https://t.co/6J2rqVrfTO

Tweet image 1
Placeholder
UltimApe@ultimapeover 4 years ago

@The_Lagrangian I think it might have an impact on my muscles because of mTor with metabolic processes possibly explaining why there are weird associations with autism and owning dogs. Lots of research on mTor in dogs. https://t.co/ZjrMEwcZA4

1 1
0 1
11/5/2024
Placeholder
UltimApe@ultimape12 months ago
Replying to @ultimape

Did I fucking stu-stu-stutter?> "They discovered that regional cerebral blood flow is reduced in the Broca’s area – the region in the frontal lobe of the brain linked to speech production – in persons who stutter."https://t.co/bpRrFnaX6C

Placeholder
UltimApe@ultimapeover 3 years ago

Did I fucking st-st-stutter?"A region in the left frontal brain is hypoactive, whereas the corresponding region in the right hemisphere is hyperactive. However, the cause of this imbalance is unclear."https://t.co/7uzxw1VqIfhttps://t.co/Dn6l8j3JPB

2 1
1 0
11/5/2024
Placeholder
UltimApe@ultimape12 months ago
Replying to @ultimape

All my my health improvements can be trace to deep impacts in my brain and nerve function.This is why I can balance on one foot with no problem for over an hour and absolutely trounce Bryan Johnson's measure of age related decline.https://t.co/H2YBoO7lao

Placeholder
David Chapman@Meaningnessabout 1 year ago

⚕️ Fascinating account of dramatic cure of multiple long-standing debilitating symptoms through self-experimentation, mechanistic understanding, and an unconventional and dangerous treatment. By @ultimape https://t.co/sSMMFEUmV1

17 2
1 1
11/5/2024
Placeholder
UltimApe@ultimape12 months ago
Replying to @ultimape

Have you considered talking with your doctor about looking at your gut health and trying gut targeted interventions or even going full FMT?Not a dog's obviously... but maybe from a lab tested human donor?https://t.co/DbHmfAUBFI

Placeholder
UltimApe@ultimapeover 1 year ago

I have been hoping to work w/ medical researchers to try and get proper safety trials done before releasing the process to the public for review.But I believe in explaining how seriously I took this process I can dissuade people from doing it themselves.https://t.co/rqYR6tcvjF

16 3
1 0
11/5/2024
Placeholder
UltimApe@ultimape12 months ago
Replying to @ultimape

yes. I have stood on one foot for an hour to confirm this. I'm fucking crazy.

1 0
11/5/2024
Placeholder
UltimApe@ultimape12 months ago
Replying to @ultimape

Why?"An increased risk of autism was seen after pediatric ischemic stroke, particularly in individuals with comorbid epilepsy, and could not be explained by being born preterm or small for gestational age." [2022] https://t.co/fSIaFhsBmahttps://t.co/IP6JXz5IQ5

Placeholder
UltimApe@ultimape12 months ago

@eigenrobot "We looked at the cerebellum because it is one of the first brain regions to begin developing and one of the last to reach its maturity, but it remains understudied" https://t.co/lKzhpC2GXmBrain inflammation => cerebellum bloodflow => stroke risk.https://t.co/BpiRTURhqk

0 0
1 0
11/8/2024
Placeholder
UltimApe@ultimape12 months ago
Replying to @ultimape

Suffer gladly.https://t.co/HdBp4WCU2Y

Placeholder
UltimApe@ultimapeover 1 year ago

@eigenrobot I suffer gladly.https://t.co/kHCLkuGUQv

1 0
1 0
11/17/2024
Placeholder
UltimApe@ultimape10 months ago
Replying to @ultimape

It was a good hoodie.https://t.co/uGH8hOCv2a

Placeholder
UltimApe@ultimape10 months ago

My health issues were so bad, I got married in matching energy drink hoodies because my ex-wife would give them to me as presents.https://t.co/iHNrXkzVVf

1 1
0 0
1/5/2025