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🧵 Thread (49 tweets)

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UltimApe@ultimapeabout 1 year ago

I've been experimenting lately to see if I can harbor acetate making microbes in my gut. Neutralizing small amounts of alcohol & turning it into acetate & eventually butryate should super-power my gut health. Butryate producers need lactate as well. https://t.co/cNUkQscgWg

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Mg2+ Papi, the BowTied Mg2+@Grimhoodabout 1 year ago

All the nonsense cell line studies aside, acetate acts as a precursor for bicarbonate/CO2 particularly in the liver and skeletal muscles on a 1:1 ratio basis, as well as nourishing butyrate-producing bacteria in the gut microbiome.

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8/17/2024
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UltimApe@ultimapeabout 1 year ago
Replying to @ultimape

This may be partly why the "with mother" brands of vinegar help.Another source of acetate (acetic acid) is from kombucha. Tho the alcohol is removed from many store brands, which means those bacteria have no food!

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8/17/2024
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UltimApe@ultimapeabout 1 year ago
Replying to @ultimape

There's a lot of complexity here, and a lot of the species of butyrate producers aren't well understood, but some of the fundamental ones that seem to go missing after covid seem to love acetate and lactate as a fuel source. https://t.co/um5hbn4f4w

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UltimApe@ultimapeabout 1 year ago

@jonvoightscar1 Sometimes this is indirect and unintuitive tho. E.g. Bifido make acetate and lactate, and then Faecalibacterium prausnitzii turn around and make butyrate from that. https://t.co/NGcNUppO5m https://t.co/lZdBS0dQqg

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UltimApe@ultimapeabout 1 year ago
Replying to @ultimape

Getting my gut to be more resilient to alcohol might neutralize that weird phenomena where we found some bacteria (associated with Alzheimer's) make alcohol and could be a source of NAFLD.Turning a threat into an asset.https://t.co/CJy8PVqVQw

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UltimApe@ultimapeover 5 years ago

Wondering about training my gut bacteria to make it so I can drink wine without getting innebreiated by acting as a substitute for substitute for alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH)https://t.co/XUZXFrei6w https://t.co/bTsihzWlDK

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8/17/2024
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UltimApe@ultimapeabout 1 year ago
Replying to @ultimape

Have you now, or ever had a sulfites allergy?What do sulfites do? They kill that acetate making bacterium. It's to preserve the sweeter wine from going sour and turning into vinegarhttps://t.co/ZwkwS82VgD

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UltimApe@ultimapealmost 2 years ago

@MeFromBefore @goblinodds @mechanical_monk Also, I have experimentally proved that sulfites cause me headache hangover.Sulfites kill gut bacteria, but all the doctors that research sulfites say it is impossible because they hyperfocus on sulfite allergy being rare.

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UltimApe@ultimapeabout 1 year ago
Replying to @ultimape

Anyway, I am not a doctor. But I can say that Jägermeister was originally invented as a medicinal and it is surprisingly tasty mixed with kefir.https://t.co/gnXLvL5SvO

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UltimApe@ultimapeabout 1 year ago

@seconds_0 @cynomaxxx Anyway, I'm about to spike my Organic Lifeway Kefir with Jägermeister and then go look up if Cocaethylene could be naturally produced by pathogenic bacteria producing alcohol in the gut.

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UltimApe@ultimapeabout 1 year ago
Replying to @ultimape

I mean, like I hate the taste of licorice... so "kinda tasty" means its not completely awful.

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8/17/2024
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UltimApe@ultimapeabout 1 year ago
Replying to @ultimape

I don't actually recommend this unless you are intimately familar with your gut health and response to alcohol.I have the timing down so I can drink an entire bottle of 151 in a night and not black out, I also know my genes tied to alcohol tolerance https://t.co/XDg81rVXRO

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UltimApe@ultimapeover 2 years ago

Huh, I don't seem to have rs2298753 genotyped in mine. Just says "not determined".And where me and her differ, I've always got the ultra rare (for Europeans to have) according to SNPedia. This explaining my weirdness here.Nothing stands out for her tho.

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8/17/2024
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UltimApe@ultimapeabout 1 year ago
Replying to @ultimape

I'm also willing to take drastic measures if I fuck and my my poop turns white (liver failure). These risks of experimenting with alcohol are not ones I take lightly, and for me I have mitigated many of them.https://t.co/PVDKnSrCFL

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UltimApe@ultimapeover 1 year ago

@AlexJournal2019 @thepowerofozone White poop for a long period of timing is an alarming symptom of liver failure. It can be a side effect of some medications. I've seen some shit...https://t.co/ofo5LSUunX

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UltimApe@ultimapeabout 1 year ago
Replying to @ultimape

Also, my goal isn't to get shiftaced, but to make it so alcohol doesn't inebriate me. I have a suspicion that medicinal uses of alcohol in the past was a different experience than it was today.https://t.co/TZZMmG09dM

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UltimApe@ultimapealmost 4 years ago

Fly Agaric mushrooms have been deemed an illegal fruit since the Bavarian Beer Act from 1516.https://t.co/Q3O9ZZTFKE

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UltimApe@ultimapeabout 1 year ago
Replying to @ultimape

If you think someone trying to drink more alcohol to cure liver problems is a smart person to emulate, please check yourself before you wreck yourself.I am not a smart man.https://t.co/BxJDz462Td

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UltimApe@ultimapeabout 1 year ago

Do you think there may be a connection between gut health factors tied to butyrate and liver health?I do. I write about it a lot! https://t.co/vAJJpsO6PF

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8/17/2024
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UltimApe@ultimapeabout 1 year ago
Replying to @ultimape

Fuck aroundhttps://t.co/QE0XnlEci4

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UltimApe@ultimapeabout 1 year ago

@Grimhood One of the reasons why I had my GF drink GT's kombucha regularly was to give her a palatable source of acetic acid. I think that and the lactate from the kefir were synergizing in her like they did in me and contributed to fighting her PCOS/Diabetes Type II

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8/18/2024
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UltimApe@ultimapeabout 1 year ago
Replying to @ultimape

Find out.https://t.co/HgmRlTGkBn

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UltimApe@ultimapealmost 2 years ago

GF no longer has PCOSGF no longer has Type II diabetesGF no longer has chronic pain and inflammation that impairs her movement.She's getting strongerShe's starting to get feeling back in her fingers and heal her dry cracked skin.Fix. your. gut.https://t.co/kiTZceIMRF

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8/18/2024
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UltimApe@ultimapeabout 1 year ago
Replying to @ultimape

I can't afford it this month, but if you're in Vermont, the large 1.750L thing of Jägermeister is on sale @ 802 spirits.https://t.co/fIRZlZvenz

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UltimApe@ultimapeabout 1 year ago

@seconds_0 @cynomaxxx I went thru about 750ml of Jägermeister and a bottle of kefir and now I don't have any lingering lung issues, my nose is clear as a whistle, and I feel well rested again.

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9/6/2024
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UltimApe@ultimapeabout 1 year ago
Replying to @ultimape

"Here's a health to the company and one to my lassLet us drink and be merry all out of one glass;Let us drink and be merry all grief to refrainFor we may or might never all meet here again" 🎶https://t.co/fn63c8FfLJ

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9/6/2024
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UltimApe@ultimapeabout 1 year ago
Replying to @ultimape

Old traditions butchered by time.> A second method is to drink from the same container at the same time using drinking straws made from hollow reeds or bamboo.https://t.co/MJy7z4O1nKEnkibru, is that you? Drink of the gods...https://t.co/GZo1D5dXqk

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UltimApe@ultimapeover 3 years ago

"In a paper aptly titled “Party Like a Sumerian” published Wednesday in the journal Antiquity, archaeologists present a meticulous re-examination of these objects and argue they are likely more ancient beer bongs than scepters."https://t.co/raqeKRtFuP

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9/6/2024
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UltimApe@ultimapeabout 1 year ago
Replying to @ultimape

Gotta go fast.https://t.co/6aHPEenpEJ

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UltimApe@ultimapeabout 1 year ago

I realized that all my crohn's symptoms were because one of my TRP receptors weren't responding right. But Kefir seemed to help a lot, especially after that fast/gut rest.Why? I guessed it was less gut lactate build up.https://t.co/PTvYSLCN5o

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9/7/2024
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UltimApe@ultimapeabout 1 year ago
Replying to @ultimape

We should probably figure out why alcohol impacts telomeres. https://t.co/PtXduEo1HT

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UltimApe@ultimapeover 2 years ago

@DollyZoom66 Its amazing how much bile health and alcoholism are tied to weird aging factors."Our findings indicate that alcohol consumption may shorten telomere length. There are implications for age-related diseases." https://t.co/DzpVp5RuPvhttps://t.co/PMAJVBQll6

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9/8/2024
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UltimApe@ultimape12 months ago
Replying to @ultimape

I'll race yah.https://t.co/sqLSnHW3bq

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UltimApe@ultimapeabout 3 years ago

@BeingJoshua @Grimhood There's a ton of magnesium lactate in my favorite energy drink, which might also be hitting Krebs cycle too? It sounds like the bowel impacting effects of Mg lactate was what may be treating the constipation I was having. https://t.co/LOXTMeoIF5

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9/25/2024
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UltimApe@ultimape12 months ago
Replying to @ultimape

Funny thing, this.https://t.co/kr6JLoE3X9

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9/25/2024
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UltimApe@ultimape12 months ago
Replying to @ultimape

Seems to me we should throw a RAGErhttps://t.co/D3mt7G5Rku

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UltimApe@ultimapeover 1 year ago

@evsthename @NovaStarpaws RAGE stands for "receptor for advanced glycation end products" and is directly involved in inflammatory response.https://t.co/3vWtfxM7sQ

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9/25/2024
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UltimApe@ultimape12 months ago
Replying to @ultimape

Rage against the dying of the light.https://t.co/32lT9OjW1f

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UltimApe@ultimapeover 2 years ago

@GENIC0N Rage against the industrial food complex machine.https://t.co/JWV5U99A4o

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9/25/2024
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UltimApe@ultimape12 months ago
Replying to @ultimape

I went blind in one eye and recovered it from it. This is a joke about odin's wisdom and my own journey thru hell.https://t.co/4GB37nK6Sp

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UltimApe@ultimapealmost 3 years ago

@bradstradamus @AaronEstel @JimmyRis In the land of blind scientists, the one eyed man says "They're the same picture", but is laughed at and told that we need more studies to confirm it.https://t.co/bcogVB454O https://t.co/I80WwoWpwO

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UltimApe@ultimape12 months ago
Replying to @ultimape

What kind of yogurt?https://t.co/XwxEEZJckv

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UltimApe@ultimape12 months ago

If one rotten apple spoils the bunch, why get pissy about it? Just learn to make hard cider.

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9/25/2024
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UltimApe@ultimape9 months ago
Replying to @ultimape

Skill issue?😂Gut issue.https://t.co/UBcYdV530C

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12/10/2024
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UltimApe@ultimape4 months ago
Replying to @ultimape

> "The researchers stress that chimps are unlikely to get "drunk"—as this would clearly not improve their survival chances." https://t.co/PYbWMSTayyBet not. https://t.co/Q27N8xVFHC https://t.co/TCcP3wxxXK

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5/12/2025
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UltimApe@ultimape4 months ago
Replying to @ultimape

Not that hard to imagine the chimps using a straw given they use them for fishing out ants.https://t.co/NAqHK0njaB

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UltimApe@ultimapealmost 4 years ago

@ensi_gudea Apparently there was some found laced with lapis lazuli and many were made of gold. I cant find out what they would have been called. https://t.co/ryDLyJ26Gz

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5/12/2025
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UltimApe@ultimape4 months ago
Replying to @ultimape

> "The rescued chimpanzees at Chimpanzee Sanctuary Northwest modified their drinking fountain by inserting a straw." @gork is this true?https://t.co/Uj7THk17IM

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5/12/2025
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UltimApe@ultimape4 months ago
Replying to @ultimape

@gork It puts the lime in the coconut and drinks it all up.https://t.co/JRvS3UeNKP

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5/12/2025
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UltimApe@ultimape4 months ago
Replying to @ultimape

@gork "scientist have long suspected that some monkeys like to get drunk... But this 17 year long study provides the first empirical evidence...."https://t.co/tlxV8Wwu2x

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5/12/2025
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UltimApe@ultimape4 months ago
Replying to @ultimape

@gork > "Dudley, [...] spent the ensuing years accumulating evidence for this hypothesis, which he presents in a new book, "The Drunken Monkey, Why we drink and abuse alcohol" (UC Press 2014)."https://t.co/GHN20Otsuw

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UltimApe@ultimape4 months ago
Replying to @ultimape

@gork > "In addition to introducing this new theory of the relationship of humans to alcohol, the book discusses the supporting research, implications of the hypothesis, and the medical and social impacts of alcoholism."https://t.co/Ra2iOV8pwVoh, OOOOH. neat.https://t.co/jBvosz7k4O

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UltimApe@ultimape4 months ago

Books I want but can't afford.A book on how animals self medicate, a book on gut health, and book on herbal treatments for dogs. https://t.co/PddziBW7XH

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UltimApe@ultimape4 months ago
Replying to @ultimape

If only there was some explanation for my weird brambly thread on turning alcohol into muscle building butyrate.https://t.co/aZqY4k4zGN

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UltimApe@ultimapeover 3 years ago

A chimpanzee is estimated to be 1,250 to 2,000 lbs bench and 441 lbs grip strength. (according to unsourced zooologist[dot]com: https://t.co/4Vc27FHMIM ). Seems a big factor is their tendons are stronger.Gorillas can apparently crush crocodiles. https://t.co/3HupFDasqI

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UltimApe@ultimape4 months ago
Replying to @ultimape

I don't seem to experience much pain anymore.Am I becoming a Ulfheðnar? https://t.co/MjFeGOavZ7

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5/12/2025
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UltimApe@ultimape4 months ago
Replying to @ultimape

Thoth willing, I will become an avatar of the monk(ey)-king.https://t.co/wU85Q3hglI

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UltimApe@ultimapeover 3 years ago

@pee_zombie @ecree429 @esrtweet woof"Aani is the dog-headed ape sacred to the Egyptian god Thoth." https://t.co/ImHLaTFB7xhttps://t.co/ULc51dCvbA

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UltimApe@ultimape4 months ago
Replying to @ultimape

A race of dog headed humans? Can I get a show of hands on who thinks that some stories associated with Cynocephaly may have been talking about baboons?https://t.co/hAPLhQ703h

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5/12/2025
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UltimApe@ultimape4 months ago
Replying to @ultimape

We gotta stop monkeying around.https://t.co/lbsl2HGNyR

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5/12/2025
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UltimApe@ultimape4 months ago
Replying to @ultimape

Humans think they are so smart, getting drunk and killing people with cars. Meanwhile a rat can avoid obstacles. https://t.co/bLZZ7HloyH

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5/12/2025
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UltimApe@ultimape4 months ago
Replying to @ultimape

The researchers stress that humans are unlikely to get "drunk"—as this would clearly not improve their survival chances.https://t.co/4eyKhdwhoB

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UltimApe@ultimape4 months ago

"More Auto Deaths in One Year than Entire U.S. Losses in The World War" Winsor McCay Comic, May 11, 1925https://t.co/UR7zdCMs9Shttps://t.co/yLIAcZ2bbO

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UltimApe@ultimape4 months ago
Replying to @ultimape

Remember, apes can't swim, their bones are too heavy.https://t.co/dvd6vfoj6g

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5/12/2025
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UltimApe@ultimape4 months ago
Replying to @ultimape

> "It has been argued that human culture rests on a unique ability to learn from others more than we could possibly learn alone in a lifetime. Two studies show that we share this ability with bumblebees and chimpanzees." (h/t @LChittka on bluesky) https://t.co/0Tp3RXOC5c

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5/12/2025
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UltimApe@ultimape4 months ago
Replying to @ultimape

I learn more effective value by watching bees and great apes than I do other humans.https://t.co/y7VWAgq4J7

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UltimApe@ultimape9 months ago

@PGC1a_RB Monkey see, monkey doo!https://t.co/elFB3M9WJPhttps://t.co/ifIWgfYeRK

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5/12/2025
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UltimApe@ultimape4 months ago
Replying to @ultimape

If only other humans did the same.https://t.co/zC1lLyZCzi

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UltimApe@ultimapeover 4 years ago

@selentelechia Ants and bees are able to self medicate when they are sick. I reasoned thru and found out that many of the pesticides that are bad for bees impact their sense of smell and impair this ability. I reasoned just needed to fix my nose for this effect to work:https://t.co/GaIb99dFJA

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UltimApe@ultimape4 months ago
Replying to @ultimape

If only humans did the same.https://t.co/Ihyx85hjjC

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UltimApe@ultimapeover 5 years ago

“The men of experiment are like the ant; they only collect and use. But the bee gathers its materials from the flowers of the garden and of the field, but transforms and digests it by a power of its own.”― Leonardo da Vinci, Leonardo's Notebookshttps://t.co/at27CLBq2Q

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5/12/2025
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UltimApe@ultimape4 months ago
Replying to @ultimape

"Oh, I’m a man with a humdrum life, stuck in a city grind,I’ve had enough of the daily stuff, it’s messin’ with my mind.I wanna be a king, Louie’s thing, and swing from tree to tree,To live just like that jungle cat, so wild and fancy-free!" 🎶https://t.co/w3u1cW9iyJ

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UltimApe@ultimapeabout 5 years ago

If an orangutan could speak, do you think he'd teach his friends?Orangutan can invent their own words and use tools. Have shared culture. The person here is hinting at trying to reintegrate this one into the wild to seed sign language.https://t.co/cnWAEcxqXY

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UltimApe@ultimape4 months ago
Replying to @ultimape

We should be more humble about our knowledge of nature, and our cousins in the wild. They have much to teach us, if only we'd listen.https://t.co/np1m0mXFrh

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5/12/2025
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UltimApe@ultimape4 months ago
Replying to @ultimape

Even monkeys can make dogs into pets.https://t.co/BNDBDblC5z

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5/12/2025
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UltimApe@ultimape4 months ago
Replying to @ultimape

"The more we learn about chimpanzee behaviour and intelligence, the more I think we come to understand how little we as humans actually know about the natural world" https://t.co/CnChFjd1UB

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5/16/2025
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UltimApe@ultimape4 months ago
Replying to @ultimape

Monkey smart.https://t.co/zfRJBFV6oy

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UltimApe@ultimape4 months ago

What kind of alcohol, bryan?https://t.co/izgFcFjHnw

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5/17/2025