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Captain Pleasure, AndrĂ©s GĂłmez Emilsson@algekalipso‱ about 1 year ago

For all my new followers: Guys, you remember how anesthesia was discovered and then _not used_ for about 50 years? Yeah, for 50 years it was known that nitrous oxide, ether, and chloroform could abolish the pain of surgery and yet _nothing was done about it_. Well, it turns out right now there is a disease that's far more painful that surgery without anesthesia called cluster headaches. Standard medicine isn't very effective against it. It's 10/10 pain for 1-3 hours 1-3 times a day 3 to 12 months per year. Huge suicide baserate in sufferers (nicknamed "suicide headaches"). Pain is literally worse than receiving a gunshot. It's certainly much more painful that surgery without anesthesia. And guess what? DMT can be used to abort it in seconds, even at sub hallucinogenic doses for some patients. This is, I argue, literally one of the absolute most important EA cause areas right now, and almost nobody is working on it. If we get our act together, we could literally abolish this hell in the span of years. Will we?

1.2K 150
7/31/2024
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Captain Pleasure, AndrĂ©s GĂłmez Emilsson@algekalipso‱ about 1 year ago
Replying to @algekalipso

See my TEDx Miami talk about this and other low-hanging fruit for drastically reducing extreme suffering in the world. https://t.co/PeRTsDPrHh

170 8
7/31/2024
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Mage of Aquarius (taylor's version)@mage_ofaquarius‱ about 1 year ago
Replying to @algekalipso

At my last "real" job I had a coworker who suffered from migraine headaches. I was trying to work up the nerve to talk to him about psilocybin's efficacy in treating migraines but we never got there. I chatted quite openly with a patient there with MS who was using psilocybin to treat depression and death anxiety. But couldn't bring myself to discuss it with my coworker. Healthcare tends to lean conservative around these topics IME. It can be a little daunting to face the fact that, as a whole, our species is quite regressive and reluctant to actually treat pain and disease because of our attitudes around pain and disease itself (believing that suffering is good and necessary, constituting an attitude I would characterize as nonconsensual internalized obligatory societal latent sadomasochism) and around certain forms of medicine and their validity. It's part of the reason I got my tattoo, the rod of Asclepius, symbolizing my connection to plant medicine. These tools are very old but humanity has this resistance to understanding that they can be safe and effective forms of medicine. Championing their use requires a lot of bravery. So I will always support you in this.

37 2
7/31/2024
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Lucifer Lucifero@jbfly46‱ about 1 year ago
Replying to @algekalipso

@algekalipso LSD has shown to possibly cure cluster headaches, and if DMT can abort them then so can psilocybin mushrooms due to how chemically similar they are to DMT.

33 0
7/31/2024
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Captain Pleasure, AndrĂ©s GĂłmez Emilsson@algekalipso‱ about 1 year ago
Replying to @jbfly46

@jbfly46 Yes absolutely. DMT is more versatile and cost effective. Many sufferers only need one 5 minute trip every 3 weeks and they stop having clusters forever. It also works within seconds to abort. LSD takes half an hour, which is a big deal with this utility monster.

81 1
7/31/2024
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Dr Diego Caleiro đŸ„©@diegocaleiro‱ about 1 year ago
Replying to @algekalipso

@algekalipso This seems like something far easier to pass in latam and Europe than USA You should use Spanish to advocate it

38 0
7/31/2024
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Captain Pleasure, AndrĂ©s GĂłmez Emilsson@algekalipso‱ about 1 year ago
Replying to @diegocaleiro

@diegocaleiro Thanks. Yes, I do have a bucket of social capital on Mexico I could pull anytime for e.g. a couple high profile interviews in national newspapers. But in waiting for the right time and framing. Perhaps I should just go for it.

74 0
7/31/2024
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Eric@aporeticaxis‱ about 1 year ago
Replying to @algekalipso

@algekalipso @ChiefQuant I remember the bad days. Know it’s been better more recently but if you haven’t seen this, may it be useful!

21 0
7/31/2024
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Devin Alvarez@DevAlpharex‱ about 1 year ago
Replying to @algekalipso

@algekalipso Very interesting, thanks for sharing, I wasn't aware. Let's launch a trial?

17 0
7/31/2024
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on godot@on_godot‱ about 1 year ago
Replying to @algekalipso

@algekalipso Oh no, here we go again. Have you heard of Emgality or Nurtec? They’re protein inhibitors. Or Botox? From someone who suffered from migraines that could not be cured with tryptophans. And who has experience with hallucinations, including during migraines.

19 0
8/1/2024
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Boris Bartlog@BorisBartlog‱ about 1 year ago
Replying to @algekalipso

@algekalipso The history of anesthesia is not so grim as that, both nitrous oxide and chloroform were put in to service not long after their anaesthetic properties were discovered.

26 0
8/1/2024
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Captain Pleasure, AndrĂ©s GĂłmez Emilsson@algekalipso‱ about 1 year ago
Replying to @BorisBartlog

@BorisBartlog Where are you getting your facts from? I read this whole thing last year: https://t.co/N911MJ1mkL..

25 0
8/1/2024
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Abby Lutz-AZ@thedeathdojo‱ 12 months ago
Replying to @algekalipso

@algekalipso @BorisBartlog They also did surgery without any but with hypnosis

1 0
10/6/2024
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Taijitu Observer@taijitu_sees‱ about 1 year ago
Replying to @algekalipso

@algekalipso I get icepick headaches a few times a year but they're gone in about 10 seconds. No clue what I'd do if they lasted an hour. I'd still like to never experience them again. Once they came with an migraine aura and I thought I was dying or something as my vision flickered.

22 0
8/1/2024
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Casey William Hardison@asthouwilt‱ about 1 year ago
Replying to @algekalipso

@algekalipso What’s EA? And another brilliant missive..

18 0
8/1/2024
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PUNISHED Chris Beignet đŸ”» PhD OBE MBA (6'5)@CHECKYSTOMPER69‱ about 1 year ago
Replying to @algekalipso

@algekalipso DMT is unlikely to be patentable without some kind of stupid adminstration device. Best option is trying to raise funds for a proper clinical trial. Also what kind of dosages are we talking here? Sub-psychedelic? Anything over 10mg is going to be a hard sell to the FDA.

25 0
8/1/2024
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Captain Pleasure, AndrĂ©s GĂłmez Emilsson@algekalipso‱ about 1 year ago
Replying to @CHECKYSTOMPER69

@CHECKYSTOMPER69 3mg hits every 5 minutes until pain subsides. Barely psychoactive really.

35 0
8/1/2024
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DeepFish📐@dip4fish‱ about 1 year ago
Replying to @algekalipso

@algekalipso Do you know if dmt if efficient against neuropathic pains?

16 0
8/1/2024
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Captain Pleasure, AndrĂ©s GĂłmez Emilsson@algekalipso‱ about 1 year ago
Replying to @dip4fish

@dip4fish I don't know how well it works. But af Eulosina in Mexico I was told several neuropathic pain patients benefitted a lot from high dose psilocybin https://t.co/FZAQDBiRjI

18 0
8/1/2024
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Casey William Hardison@asthouwilt‱ about 1 year ago
Replying to @algekalipso

@algekalipso Korzybski’s thought created new possibilities in quantum mechanics. This book will alter your perception of reality. https://t.co/Db7TwTae2Z

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17 0
8/2/2024
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.perchUpon {@perchUpon‱ about 1 year ago
Replying to @algekalipso

@algekalipso I was going to say do those people who have those headaches ever try regular MJ? Definitely would expect DMT to have an effect.

17 0
8/7/2024
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CARZEN@e0syn‱ about 1 year ago
Replying to @algekalipso

@algekalipso My headaches brought me to the floor of the fast food joint I was working at some years back. Don't wish that hell on anyone. Apparently, you're supposed to go to the hospital when they affect your vision... I'd have a lot of bills if I did. Yeesh

17 0
8/29/2024
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Joshua đŸ’«@workflowsauce‱ 11 months ago
Replying to @algekalipso

@algekalipso Crazy

1 0
10/13/2024