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Cold is thirst, Thirst is water.Of course.I see it now. https://t.co/ZwtUNK0jI4
It's blood bending.https://t.co/8xGoF4JrGyhttps://t.co/OM25RWbeQtBlood flow. Vascular tone. Yes.
I've been growing my blood vessels.https://t.co/vVYVWttMvY
Fixing blood flow and secretion.https://t.co/KAlhQToCnOWould this work on Sjogren's Related Dryness?Does my skin get dry during the winter because TRPM8 activity goes away?
The pain disappears.https://t.co/lorD7AxPjT
Some ancient healing magic, this.https://t.co/1Df2FvaRWs
BRB going to binge watch a cartoon https://t.co/W0wCDcDC5K
Talking with GF about using her netflix.Started talking about various 'spirits' and their relationship to alchemyNymphs/Undine = Water SpiritSylph/Sylvestris = Air SpiritPygmy/Gnomus = Earth SpiritSalamander/Vulcanus = Fire Spirit But??? / ??? = Void (love?) Spirit
Tree spirit = Earth Spirit?Is this a gnome? 🍄🐿️https://t.co/BKGTHJEEs1
This one is a little on the nose. https://t.co/n6v3atO25Y
Giant Mecha TankCarrying a Heavy Gustav.Shooting "Spirit Bombs".https://t.co/0n8wF34h5a https://t.co/GK8r9AjU5e
Ah yes. a "Spirit Bomb" https://t.co/e3sFoiH52z
Do you ever try to unlock your chi by activating TRPV1 to help blood vessels expand?https://t.co/xYSgbB3Itx
I stopped an anxiety spell by taking tincture of cayenne and then getting in warm shower. I stopped sweating as a result.Recognized I was turning on my TRPV1 receptors as a result of an immune shift targeting liver enzymes and anandamide production.:3https://t.co/RKFKfbV4EC
Why would relaxing smooth muscle tissues, and then hanging upside down to increase blood pressure, aid in creative brain work? https://t.co/e2aqz721GG https://t.co/dIY3UJdHuc
Ah yes. The sphincter of the eye."In a cross section of the iris, the sphincter pupillae can be seen as an annular band of smooth muscle (100–170 µm thick; 0.7–1.0 mm wide) encircling the pupil (figure 7)." https://t.co/FD6IAIxzcdhttps://t.co/t6oLYuZ55V https://t.co/tbzoaTC6LR
I wonder if anyone has ever thought to correlate spleen engorgement with moon cycles.https://t.co/tjYhZGK2HQ
Spleen development regulated by gut microbiota?https://t.co/uwTDr5SHgSSpleen's own microbiota is modulated by tick infections.https://t.co/TvTNmN09olTraditional Chinsese Medicine's model of spleen health might be via blood microbiome?https://t.co/OPF2aouC3INice.
ha. haha. Haha. HaHa HAHA. HAHAHAAHAHibernation? Getting trapped in the spirit world.https://t.co/FGpC3y39Kbhttps://t.co/gKHyCKBIMW https://t.co/tuoEr5rzSw
It contains truth within the myth.https://t.co/DCpqlrMu1x
@QunolOfficial No, but my model of human hibernation made predictions that adolescence would have poor bone development. Ended up being found on fossil records of early humans. It turns out this is a process driven by kidneys & vitamin D. Related:https://t.co/wTxpnMIWEGhttps://t.co/6znEkhM9QX
One of the more interesting themes in the show was how often a wise character understood there was wisdom in some of these methods, but was doing it wrong.Surrounded by Yes-Men, Varrick needed an outsider perspective to tell him. https://t.co/SEilKo28On
Sometimes you need outside context to see into the meaning behind a thing.For example, this funny looking tiger striped war ship was based on a real idea "Dazzle Camouflage"https://t.co/0ECZ9NVmrD https://t.co/629hFfseOL
"The Guide" story arc is fun here. It showcases how one's ego and knowledge can hide the truth. Tenzin has been researching this stuff all his life, but it was his child who actually managed to act as a guide.Should have ate some onion banana juice TBH.https://t.co/hrT8pI22VU https://t.co/q1S1YGf4zy
These notions are brought up again in 3rd season.That whole mediate->levitate thing Varrick was trying to do was actually achieved by Zaheer. Even the expert didn't think it was real.Shame they didn't incorporate any of the fraudulant flying techniques https://t.co/GYah9nhC5f https://t.co/uewvzsOU59
Bolin unlocked his lavabending while staring death in the face.Zaheer had literally just watched his love die and lost everything he was attached to.Deep wisdom, this. https://t.co/b8bgabQXjB
>'pataphysics as an idea that "the virtual or imaginary nature of things as glimpsed by the heightened vision of poetry or science or love can be seized and lived as real"https://t.co/ZiKNAUbINw https://t.co/oqy4w60SPN
The whole 4th season is a giant parable about trauma, unity, and forgiveness. Literal and metaphorical.They use aspects of WWII across cultures as the backdrop, but in the context of family bonds. Its really fascinating.Even ends in a wedding! (two, if you squint)
I am still hoping to decode some of the things I see. They go out o the way to make them screenshot-able.There is a lot of fun lore about Pai Sho that spreads over all of Avatar https://t.co/OEAjQHsG9D https://t.co/nzLWEPuHPF
I also see fascinating symbols everywhere.(Took me 10 minutes to get the writing in that book🤭) https://t.co/kWW38fLA0N
I think its fascinating that the poison they use to force the Avatar state is a sort of mercury lingam.https://t.co/MtB8LR1WR0The title of this episode is "Venom of the Red Lotus". I wonder if the flowers represent the ones used as part of "Shiva Puja" https://t.co/z9brM5t18h https://t.co/f4lK3kXjRW
The air temple island is also quite strikingI think that is a Yin Yang and a Ba gua on the ground.Its fascinating that air bending styles may be loosely modeled after Baguazhang - "Circle walking" https://t.co/YXIVZQdwg1I don't recognize the other styles. https://t.co/vsQmov8yA4
This covers most of them fairly well.It looks like the other style I saw may have been 'Xing Yi Quan' https://t.co/WBcgjrRCG3
I binge Korra, sleeping halfway thru. So in total it took about 29 hours. I didn't eat much except peanuts. Got a massive headache, fatigue. Couldn't hardly think/talk. GF pointed out my eyes were bloodshot. Blood pressure was quite high.You'll never guess how I fixed it :) https://t.co/KL3EDIXhGj
Blood bending."Activation of TRPV1 by capsaicin exerts an anti-hypertension effect by promoting the release of calcitonin gene-related peptide (CGRP) from capsaicin-sensitive nerves and nitric oxide (NO) from endothelial cells."https://t.co/8yzmpiP0Qp https://t.co/vGgq5OVaM2
Moon's push and pull. https://t.co/ku9KRyvdNC
Moon sure is pretty tonight.https://t.co/z9VOj7yMfx
I met a witch, she taught me about blood bending.https://t.co/2PF0mqcg9V
yandex's translate tool got this https://t.co/siCa9N4739
https://t.co/We0NlgO5ou did sorta ok grabbing the characters,But some of them aren't quite right. and there are missing ones.產雙進中南 生入精北 南能物中申北量質古靈門對界融户流界戰
Aren't there entire religions that see cannabis as a sacred plant with healing properties? https://t.co/VwmubzP4fXAre they natural blood benders?https://t.co/VBu96kRBnA
Protip: if you downregulate TRPM8 receptors you can avoid feeling thirsty. It also might be one of the ways to prevent damage from stroke and heat disease. https://t.co/2Of8H0C0TlLikely why my body temperature drops so low. It seems functionally tied to anxiety via serotonin.
It's really interesting that mice without TRPM8 seem to have improved insulin clearance.https://t.co/v5M21uxIDxand that TRPV1 makes my GF's blood pressure drop. Gonna see if it makes her not sweat.https://t.co/Ec7G3prPooWhy does diabetes occasionally exhibit intense thirst?
"it is alarming to note the lack of information regarding diabetes and heat stress [...] few studies have examined the effects of cold exposure on individuals with diabetes with the exception of its therapeutic potential" https://t.co/1q6HPm8zgghttps://t.co/CJgqdtWA2I
I learned in highschool that walking in the cold to the bus stop, then sitting in front of the heater would wake me up and get me to stop feeling off. I replicated it with snow and a hot shower.Of course we use it to torture autistic kids.https://t.co/dLQVR6wKrL
"wholly impossible to predict the net effect of hypothermia. [...] slow down inflammation, but it will also slow down anti-inflammatory pathways. [...] reduce intracranial pressure, but it may also reduce blood pressure and cerebral perfusion pressure."https://t.co/0gYSvgd6VS 🤔
Did you know the term "take a cold shower" as it relates to reduction of being sexually aroused originates from John Harvey Kellogg and his contemporaries?https://t.co/a0HNO49RHh
It's really frustraiting how so much of this stuff is overlooked and dismissed as preposterous because we seem to ignore or don't understand TRP receptors and Endocannabinoid system's role in immune regulation.Argumentum ad ignorantiam all the way down.
Anyway, here's a study about how TRPM8 plays a role in rat erections.https://t.co/AL6PBY0KZu
Ah yes, blood bending.That's what I'm researching. Totally not steel manning ancient models of health by assuming the weird notion of 'vital heat' was actually onto something.https://t.co/tyYZKhAt69
@ultimape https://t.co/BN5mBpsYWf
Why do my threads keep going to these weird places involving sexual function and health? https://t.co/R4avbeOpIp
I found my thread on dicks and diabetes.Viagra works afaict because it fixes blood pressure weirdness associated with smooth muscle tissue and vascular contraction. IIRC it operates on nitric oxide associated pathways. https://t.co/B3F5763hJdhttps://t.co/X0jIJCVg0p
TRPM8 makes me cry.It makes me moist.https://t.co/y9YIJ6Ovt0https://t.co/3u8YFvb0EV
So i'm over here reveiwing T cell an Treg in the eye and wondering if anyone is bothering to track dry eye symptoms in covid-19 cases. https://t.co/y5tCXsrHmuSo I had a hunch that reduced T cells would cause conjunctivitis via TRPM8 interaction https://t.co/50MBkt9UUo and yeah.
TRPM8 is involved in the sensing of bacterial lipopolysaccharides in cold temperatures.https://t.co/OxwMSMmWsdhttps://t.co/Vq18rMZEOG https://t.co/5LRwCOGujh
Not right now, babe. I've got a headache.https://t.co/b8kWi0gDYz
How are you ever going to 'ACE' that test if you don't get control of your blood pressure?https://t.co/2FwA5MK86p
I'll rue the day."There isn't enough reliable information to know how rue might work."https://t.co/2zGSQ2u9cI
Rue is used to stop a heart from beating fast https://t.co/0gG9IkycnqThis is clearly a creative way to hint that you wanna bang the girl so hard you get a pounding heart and will need medicine for it.In context where medical herbs were common knowledge, this is really kinky. https://t.co/doXdKb1sWB
"Do not use internally in small children or the elderly, and do not take rue together with medications to lower blood pressure."https://t.co/PuVv6DeNDehttps://t.co/Xunfl32Yb0 https://t.co/8159OL8zCm
I'm going to be buying a bunch of indoor gardening equipment with my next paycheck. I wanna grow plants that induce abortions.Stuff that smells good and has funny taste'ing roots.Molesting plants to make them long and hardy.https://t.co/PzS5m649NQ https://t.co/5U4DQkrFSj
Gonna bend some blood. Make an entire balloon animal out of my blood balloon.https://t.co/NS7R6OiiEi https://t.co/zLJYwhCdau
This whole space is full of fucked ideas. Stuff that is used to help induce abortions is also super important for having a healthy pregnancy. If you're against abortion medications, you're likely unknowingly against medications that help women have successful births. Its absurd.
"Other applications have been claimed, such as treating hypercholesterolemia, hypertension, coronary heart disease, diabetic neuropathy and retinopathy, erectile dysfunction, kidney disease, and pancreatitis, among others." https://t.co/4oyW0A1cxz
"our novel findings bring to light a central role ofTRPM8 in the regulation of testosterone-dependent mammalian sexual and social behaviors, as loss of TRPM8 leads to a delayed sexual satiety, altered sexual preferences, and enhanced aggression"https://t.co/5tgilayvli
Using some cold water to bend my inner fire and temper my vital heat.https://t.co/PS6HYtzpV0
Did you know that they use COLD towels to calm down people who are acting overtly aggressive?Why would excessively hitting the cold/pressure sensitive TRPM8 (a known receptor for testosterone) lead to calming?What is a weighted blanket anyway?https://t.co/IKcVbmFGbs
Sexual (hyper)tension."technology to monitor BP and HR helps us to get the real data in participants during sexual activity. BP, HR and DP increase just slightly for a short time and recover to baseline level soon after sexual activity in healthy adults."https://t.co/ZMCJPBDWS3
"High blood pressure keeps the arteries that carry blood into the penis from dilating the way they're supposed to. It also makes the smooth muscle in the penis lose its ability to relax. As a result, not enough blood flows" https://t.co/zQYSQusCVVhttps://t.co/5q27xrKus3
what exactly is going on here?https://t.co/a5K1VSMFMu
I bet TRPV2, with it's apparent role in osmosensation, is how the balloon knows to stop inflating, and so we should expect it to directly or indirectly impact TRMP8 sensitization in penile tissue.A hunch.https://t.co/HcgrCXTw1j
With Oxytocin interacting with TRPV2, we are perhaps looking at the same underlying mechanism as found here: https://t.co/W9FDalvTYw
Camphor hits TRPV2 similarly to oxytocin.So... Camphor is possibly used as a sexual enhancement aid in cases where low oxytocin or testosterone is found?https://t.co/3mZ8irZZ5k
heh"Natural remedies for impotence in medieval Persia"https://t.co/34xrN5e0cc"The claim of inhibitory effect of camphor on sexual activity could not be confirmed by this study. More investigations in this field are suggested."https://t.co/N2Gsv5x6Xahttps://t.co/zAvxhmsPJo
wat"Moreover, TRPV2 is probably the least understood member of the TRPV subfamily, and the regulation of TRPV2 in humans is unknown" [Aug 2019]https://t.co/NfqFECU2b4
TRPM8 isn't just cold. also Stretch."stretching in MCs activates TRPV1, TRPV2, TRPV4, and TRPA1 channels, that it may be involved in synaptic transmission to sensory neurons, and that MCs could contribute to the mechanosensory transduction sequence"https://t.co/Uxjf4qUpgm
Stretching helps take the pain away.https://t.co/B4TaFMUTIc
TRPM8 is just one of a number of mechanistic stretch sensors that help the body detect when something is full, or if it is thirsty.https://t.co/KZDNMA3z5R
Somewhere out there is some weird dude who literally gets hard looking at an actual tall glass of water because of TRPM8's interaction with testosterone.https://t.co/ow7H75xTvO
And someone out there is trying to dip their balls in soy sauce because they heard soy turns you into a girl.https://t.co/qibWswIoiohttps://t.co/UN2aRGBTGa
I wonder what you would have to add to soy sauce to be able to get the fermentation byproducts penetrate the scrotal sack. Do you think warmth would be enough?Also, TIL real soy sauce is a fermented food.https://t.co/BEVZANCCi0https://t.co/5SxHhMtmIe
So I was explaining to lil' bro about allergies happen b/c immune cells basically go around licking others to see what proteins are expressed on the surface.https://t.co/BAppXFAvpjHe asked me if I saw that soy sauce meme.I fucking lost it. I'm done.https://t.co/3kSV2oZPvf
Humans are dumb. We make sensors that are tuned to only give a reading under one set of circumstances. We should be thinking about the sensors as multidimensional ranges & fields; engineering overlapping fields that cancel out using computation.That's how TRP receptors work?
Our olfaction works on probability domains. The smell we sense is often mediated by what we are looking at. Sensory hallucinations are a feature of how we encode information using multi-modal sensory arrays.https://t.co/nY29VTZdmN
Vary the TRP receptor density / expression, and change how they interact to upregulate/downregulate, and you can fine tune what a body part is going to respond to.https://t.co/vg93CTif3K
Embedding a word for future me to find this idea via search:sensor fusionhttps://t.co/YaIV6VwyhC
Tired: translation AI's spontaneously inventing langaugeInspired: GAI inventing music to communicate cogent narratives about time-space constraints as a template-metanarrative network operating across sensory modalities as accident of exploring sensor fusion of embodied agents.
By your powers combined, I am a metaphor about how our body's respond to various elements as a sensory-mediated outlook on how we experience the world.Alchemy was about health & the body. Of course claims about how chemistry works would be wrong.https://t.co/Tt2TZ1DOCm
"Alkahestry (錬丹術 Rentanjutsu?), also called Purification Arts (連弾主 Rendan-nushi?), refers to the slightly different form of Alchemy used in the country of Xing."https://t.co/JU4XHz5t7Mhttps://t.co/VvxjQKvfOX
Ah yes, my brain bubbles up odd facts about a cartoon show to help me find the tweet that discusses how all these concepts are linked.https://t.co/jDTykBNgSM
One of the reasons why I wanna track my erection and sexual arousal is because of weird ties between M.S. and immune function. https://t.co/NHINWvPFWjI noticed that my arousal levels vary fairly consistently with immune factors related to M.S. Symptoms.https://t.co/5QtowzwdQR
"We also review current knowledge on the relationship between sex hormones and resident CNS cells and provide new insights in the context of MS."https://t.co/Hnem5liQCgI love how I can predict these papers must necessarily exist.
Huh"After multivariable adjustment, low liquid consumption was the predictor of constipation among patients with dementia. The findings support the clinical recommendations to treat constipation with an increased liquid intake"https://t.co/ydcETlEqWc
So what is happening in bears that downregulates their desire to drink water?https://t.co/mf1uO1Jb13
"The increased serotonin causes a decrease of oxytocin [...] and an increase in calcitonin gene-related peptide (CGRP) in the central nucleus of the amygdale, which are associated with social interactions and vital in autism." https://t.co/P7BXGltSLnhttps://t.co/omD5hjA5Jb
Blood bending."Activation of TRPV1 by capsaicin exerts an anti-hypertension effect by promoting the release of calcitonin gene-related peptide (CGRP) from capsaicin-sensitive nerves and nitric oxide (NO) from endothelial cells."https://t.co/8yzmpiP0Qp https://t.co/vGgq5OVaM2
¯\_(ツ)_/¯"Migraine is the most common brain disease in the world, but surprisingly only a few studies investigate the comorbidity between autism and migraine."https://t.co/wLUtnS5je8
I just stumble into this shit because of exploring my family history.https://t.co/yUjvlHVZLk
@Tipsycaek So maybe you're having a migraine? The etiology of migraines is weird and people sometimes don't manifest with a pain response. TL;DR: I think the pain response abnormality associated with autism are more wide spread, but no one realizes.https://t.co/sjOa0Rwc5M
Granting the Premise, as Modus operandi.https://t.co/YZKcdlQnmw
I successfully linked pandas covering themselves with horse manure and a possible lipid metabolism problem tied to autism via TRP receptor pathways. Coincide with the effect of weighted blankets and pressure.Because of reverse trolling someone who copypasta'd about feet pics.
Am I just getting weird side effects form migraines, but don't have the pain for some reason?https://t.co/RXRLXNIwyA
"This region would be distinctively associated with any polymorphism that could affect the cold sensing of the TRPM8 receptor."https://t.co/Z94mMDsIxNHeh. Thanks @nsreed https://t.co/cUdQ686TgT https://t.co/Esn5lwu2Lh
@nsreed Float like a balloon animal,wondering why I gotta go pee.https://t.co/iDcpBbjaPxhttps://t.co/zboEMDOPgP
Did you know that the association of balloons with clowns is because of people using inflated pig bladders?https://t.co/77vmEYf6KbI'm a balloonist.https://t.co/JuPzKtr8PJ
A fool. With a funny looking stick.https://t.co/F0oXPeOjM0https://t.co/m19pyzwWdS
The stick of the big monkey.https://t.co/5TFjvn4K2X
"Usually depicted as a monk with a halo around his shaved head, he carries a staff to force open the gates of hell and a wish-fulfilling jewel to light up the darkness."https://t.co/EhHQ5ZMbMAhttps://t.co/9mBldRHLEP https://t.co/jHMlWtkVge
That monk(ey) is holding an philosopher's stone.https://t.co/3SaYSgUecP
"Having mixed the red and the black parts, Brand heated them again, distilled and...hocus pocus! The glass chamber got filled with glowing fumes that turned into a shining, white liquid, which, upon contact with oxygen, produced bright flames."https://t.co/bJSaRSbNwX
Hoc est corpus meumhttps://t.co/uX0qh6VGSz https://t.co/xd9yklrTQO
How would you do this without using feces?A fermentation byproduct?"In cells exposed to the chemical in the lab, BCP/BCPO had the opposite effect, inhibiting TRMP8. That effectively makes the protein less able to detect cold, the researchers say." https://t.co/AgO9lCKb8w
"role of TRPM8 in energy metabolism and thermogenesis has been recently demonstrated, and our group was the first to establish the link between TRP channels and clock genes in BAT"https://t.co/uCtKpNdFqA
For the reader: those two quotes and links are intentionally mixed up because I want you to understand that the panda bear is not simply rolling in shit to "Feel warm", but is actually modulating their metabolism via brown adipose tissue regulation.
Gotta get that spice. BCP/BCPO"β-Caryophyllene: A Sesquiterpene with Countless Biological Properties"https://t.co/7vdX7LrfRjhttps://t.co/nXodsmP3VO
@strnglft So I tried an isolated linalool extract that didn't seem to help as much as a lavender one. I think its because lavender also has β-caryophyllene (found in black pepper and some cannabis strains). Doing something weird to CB2 https://t.co/zO9mczV8rw
Spice is nice."Studies using mice have found that the essential oil of oleoresin, Copaifera paupera, which contains β-caryophyllene, improves wound healing"https://t.co/PfVxGuPDfd
Essential oil of oleoresin you say?Why would the oil of hot peppers make me feel better?Probably that BAT activation via TRPV1's secondary sensitization of TRPM8.https://t.co/NPSXAzRl7Y
Capsaicin tincture works similar. Reduces panic and aggression in me."results suggest that capsaicin stimulates lipid mobilization from adipose tissue and lowers the perirenal adipose tissue weight and serum triglyceride concentration in lard-fed rats." https://t.co/gMDo7MxATa
A spicy bat that impacts endocannabinoid system in a way that modulates essential metabolism, both of witch antagonizes hedgehog signaling pathways and associated with wound healing?This is now a sonic hedgehog thread.Sorry. I don't make the rules.https://t.co/75J8E8SH86 https://t.co/Lok4ffX1H9
I love when ideas have sex.https://t.co/XHJZ4Fwhwr
"the genes in these signaling pathways that became significantly up/down-regulated in the [β-Caryophyllene] group [...] there were genes whose expression was dramatically increased [...] hedgehog interacting protein gene (hhip), sonic hedgehog gene (shh)"https://t.co/7WDAPikDvJ https://t.co/gwhvhFyY5X
Alzheimer's => Dry Skin"The idea of using a simple treatment like a skin emollient as one way to reduce age-associated inflammation is both intriguing and appealing, and worth further evaluation"https://t.co/VqVccnVYaW
"We predict that voltage-gated Ca2+ channels (VGCCs) along with the transient-receptor potential M8 (TRPM8) channel are crucial molecular components in Alzheimer's progression." https://t.co/EXZutUQ0F2Same