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🧵 Thread (55 tweets)

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UltimApe@ultimapealmost 7 years ago

Spent 2 hours today explaining basic DNA stuff to my mom.Now she understands how changing your diet doesn't change your genes, and how curing stuff doesn't make the genes go away.She immediately had much more intelligent questions about CRISPR. Oh no.https://t.co/nWTadgOLF7

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10/21/2018
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UltimApe@ultimapealmost 7 years ago
Replying to @ultimape

Explaining DNA Ploidy to my mom:Yay, she now understands why ants are so weird, and why it's called '23andMe'But somewhat awkward was explaining Kleinfelter, Turner's and Swyer syndrome, and Chromosome 2 (she doesn't believe Neanderthals existed.)https://t.co/mpR3eIQwSm

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10/22/2018
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UltimApe@ultimapealmost 7 years ago
Replying to @ultimape

Thought she took to the idea that the discovery of DNA has basically written out some major contributors, and she was already Familiar with X-rays, so using Crystallography to 'see the shape' was simple.https://t.co/MN0xkHlVXb

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10/22/2018
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UltimApe@ultimapealmost 7 years ago
Replying to @ultimape

I'm thinking if we can get her gene test thru 23andMe, I'll suggest going with the ancestry one. That is primarily what she's interested in, and neanderthal gene report my make her sketched out. For my health research all I really need is raw gene data anyway.

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10/22/2018
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UltimApe@ultimapealmost 7 years ago
Replying to @ultimape

I can only predict half genes from my own test, and when I don't have an identical pair, I can't really tell which came from her. The only one I can be reasonably confident about is 'x' given there a astronomically high chance it didn't come from my dad.https://t.co/GJNYqllZHG

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10/22/2018
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UltimApe@ultimapealmost 7 years ago
Replying to @ultimape

Though it would be really cool if my mom is XXY and by some fluke I inherited her Y and my dad's X. I have no idea if that is even theoretically possible, but nature is weird.

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10/22/2018
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UltimApe@ultimapealmost 7 years ago
Replying to @ultimape

That gives me an idea. I should have her watch southpark.https://t.co/8tghcaKr3C

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10/22/2018
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UltimApe@ultimapealmost 7 years ago
Replying to @ultimape

Something something, imbecile, something something haplogroup.I wonder if south-park was funnier to me as a child because I understood this stuff.This explains why all the other kids were obsessed with the fart jokes.

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10/23/2018
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UltimApe@ultimapealmost 7 years ago
Replying to @ultimape

Also, why does that show have so much humor over genetics and evolution?Makes me wonder about Matt/Trey and their influences. Has anybody written a biography of the two yet?Heh, Trey's first name is 'Randolph', and is currently CEO of "Furry Balls, inc"

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10/23/2018
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UltimApe@ultimapealmost 7 years ago
Replying to @ultimape

Ah, I get it now. Southpark is art imitating life? https://t.co/UK6mrgE8rZ https://t.co/notLyngqQS

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10/23/2018
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UltimApe@ultimapealmost 7 years ago
Replying to @ultimape

"We can't go around saving every form of life anymore than we can kill them all"https://t.co/gjy1vqT80x

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10/23/2018
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UltimApe@ultimapealmost 7 years ago
Replying to @ultimape

"in this way, disease causing mutation can be corrected"https://t.co/bOkpwHKzxn

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10/29/2018
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UltimApe@ultimapealmost 7 years ago
Replying to @ultimape

"Keep in mind, this child is still you - simply the best of you. You could conceive naturally a thousand times, and never get such a result."https://t.co/xpebIGi230

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10/29/2018
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UltimApe@ultimapealmost 7 years ago
Replying to @ultimape

"What is CRISPR?"https://t.co/95jnxX8n6X

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10/29/2018
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UltimApe@ultimapealmost 7 years ago
Replying to @ultimape

Oooh, neat. Kurzgesagt has a video on designer babies.https://t.co/v8Secc95Xw

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10/29/2018
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UltimApe@ultimapealmost 7 years ago
Replying to @ultimape

BTW, if you want a more in depth overview of DNA stuff, The MCAT test prep track on @khanacademy is quite good.The overview of "Applications of DNA technologies" is worth watching https://t.co/J7ACqZRjT7 (or via their site https://t.co/AQmc5yyZ74 which also has good comments.)

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10/29/2018
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UltimApe@ultimapeover 6 years ago
Replying to @ultimape

"the high cost of sexed semen is the fact that a single US company holds the patents for the most advanced and trustworthy sorting technology. Sexing Technologies (ST Genetics), legally registered as Inguran LLC, has a monopoly over the sexed semen market"https://t.co/MYAxDC29Xm

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1/28/2019
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UltimApe@ultimapeover 6 years ago
Replying to @ultimape

How long until we have mail-order babies as a service?https://t.co/QlDqhGkpjQhttps://t.co/yvDvBik6Ek

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1/28/2019
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UltimApe@ultimapeover 6 years ago
Replying to @ultimape

IVF in dogs... 2015https://t.co/rScykNAaMzhttps://t.co/kacRGAGdZH

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UltimApe@ultimapealmost 8 years ago

How long until wetnurses and daycares get "baby sharing" apps?https://t.co/JQSoykoKLShttps://t.co/yrOuL3x1zIIs that a thing yet?

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1/28/2019
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UltimApe@ultimapeover 6 years ago
Replying to @ultimape

I think a lot about how ants control gender by selective fertilization, and how alligator mound's internal temperature affects gender expression thru action on the TRPV4 gene and it's impact in the gonads.https://t.co/kkprnZvqsuhttps://t.co/6y5n09nKkr

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UltimApe@ultimapeover 6 years ago

@37point78 The chart in the lower right is particularly interesting.The link to this with mTOR is"TRPV1 caused an increase in intracellular calcium concentrations ([Ca2+]i) and that this activated mammalian target of rapamycin (mTOR) and promoted muscle hypertrophy" https://t.co/iX4tLDcwr8

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1/28/2019
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UltimApe@ultimapeover 4 years ago
Replying to @ultimape

If I figure out how to change gender expression by impacting gut microbiota immune profile of mother during gestation, I'm not going to tell anybody, because people will use it to disrupt delicate gender balances that ensure survival against entropy.https://t.co/p3FjS1mItq

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UltimApe@ultimapeover 6 years ago

"the high cost of sexed semen is the fact that a single US company holds the patents for the most advanced and trustworthy sorting technology. Sexing Technologies (ST Genetics), legally registered as Inguran LLC, has a monopoly over the sexed semen market"https://t.co/MYAxDC29Xm

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1/25/2021
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UltimApe@ultimapeover 4 years ago
Replying to @ultimape

Someone else is going to figure it out anyway because there is a market for it.And... oh would you look at that it's already being explored.https://t.co/Zl7riQpgpO

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1/25/2021
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UltimApe@ultimapeover 4 years ago
Replying to @ultimape

Whelp. Time to figure out how to fight a plague of mosquitoes carying bacteria that are gene-drive engineered in a way to bias the population to be all girls.https://t.co/sKLrZtazVk

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UltimApe@ultimapeover 4 years ago

Can someone explain to me why people keep referring to Nick Land as a girl? Is that some kind of swarm level shame mechanism because of his sayings on how we all become like ants in an ant colony?https://t.co/zpy1qm0oV5

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1/25/2021
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UltimApe@ultimapeover 4 years ago
Replying to @ultimape

Are you rich? Fed years of Malthusian concepts sprinkled w/ ideas of elite over production? Do you want to control the reproductive nature of a species thru centralized control & manipulation of genome to fight climate change + food scarcity? Great news!https://t.co/KH8EdPj6ID

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UltimApe@ultimapeover 4 years ago

"Gene drives could be used to benefit public health, the environment, agriculture, and animal well-being. However, real-world use may incur ecological risks, and even research involving self-propagating gene drive systems may risk public trust in science"https://t.co/Ftui5Tu22j

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1/25/2021
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UltimApe@ultimapeover 4 years ago
Replying to @ultimape

Immanentize the eschaton, today!I'm sure it won't end up with a species destroying grey-goo scenerio.https://t.co/PtaRiigo18

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UltimApe@ultimapeover 4 years ago

You think I'm doing this for fun? No.I think we're all going to fucking die and I have endless amounts of existential dread and anxiety.https://t.co/n2fp4vwAr2

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1/25/2021
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UltimApe@ultimapeover 4 years ago
Replying to @ultimape

I'm sorry I am not fast enough.https://t.co/SSYtHJ9EVv

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UltimApe@ultimapeover 4 years ago

One of the things I wanted was a DNA test so I could fix my health. I tried and tried to find another way to get my genes tested. I entered into medical trials, emailed researchers about it. https://t.co/lkEBN0eyIr

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1/25/2021
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UltimApe@ultimapeover 4 years ago
Replying to @ultimape

Please, you must understand how you are wrong.https://t.co/HpgEOEdq5x

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UltimApe@ultimapeover 4 years ago

Please reconsider.https://t.co/aocEB6WAYM

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2/1/2021
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UltimApe@ultimapeover 4 years ago
Replying to @ultimape

Please, you must understand.https://t.co/bQ3B4Hl16T

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Visakan Veerasamy@visakanvover 4 years ago

"I happened to read for my amusement..." https://t.co/8Svnv6H0Dx

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2/12/2021
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UltimApe@ultimapeover 4 years ago
Replying to @ultimape

Do you ever wake up and have your phone's news program show you articles telling you that you're right?https://t.co/bLU1XcDGvn

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4/8/2021
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UltimApe@ultimapeover 4 years ago
Replying to @ultimape

I'm not crazy at all >.>https://t.co/n94AKNRhHx

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UltimApe@ultimapeover 8 years ago

Yet another reason why I think being able to continuously test cortisol levels would be useful from #quantifiedselfhttps://t.co/TIypguwHWT https://t.co/OVZEMESdnm

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4/8/2021
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UltimApe@ultimapeover 3 years ago
Replying to @ultimape

I fixed my girlfriends menstrual cycle.I don't even want children, lol.https://t.co/NlGKLil5RY

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1/27/2022
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UltimApe@ultimapeover 3 years ago
Replying to @ultimape

People don't think shitposting be like it is, but it do.https://t.co/9VEYSxS1bM

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UltimApe@ultimapeover 6 years ago

[in a very @fire__exit voice]If I am somehow able to help women with PCOS tweak their menstral cycles to be less painful / more regular, would that make me a god among men?I will be able to have women ovulate for me on command. 😎

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1/27/2022
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UltimApe@ultimapeover 3 years ago
Replying to @ultimape

After the dog shit trial, I'm gonna aim toward bear shit. https://t.co/SVmsXt3caz

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UltimApe@ultimapeover 4 years ago

@fire__exit What you need is to find a female bear with only a minor psudopenis and eat their feces shortly before their hibernation, and only if your immune system is doing well enough that you don't lose your eyesight or ability to walk. It seems unwise in any case.https://t.co/yBRBKsQa8G

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1/27/2022
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UltimApe@ultimapeover 3 years ago
Replying to @ultimape

Do you ever spend an inordinate amount of time wondering about cat urine?https://t.co/eeg7C0hxL7

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UltimApe@ultimapeover 6 years ago

They found the maned lioness epigentic effect in mice, so thats a start.High testosterone in mothers passed on to daughters... (something that seems to play an epigenetic role in pcos, autism, and schziophrenia risks during gestation) https://t.co/7ekfD6aNnu

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1/27/2022
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UltimApe@ultimapeover 3 years ago
Replying to @ultimape

Or studying how abortion drugs impact schizophrenia and autism?https://t.co/c1oGR3Z6FA

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UltimApe@ultimapealmost 6 years ago

I'm having success with a bunch of herbal stuff I found while exploring midwife history and traditional ways of dealing with irregular menstrual cycles. This matches up with weird findings about how Gensing & Black Cohosh also seem to reduce negative symptoms of schizophrenia.

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1/27/2022
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UltimApe@ultimapeover 3 years ago
Replying to @ultimape

Or studying the history of eugenics.https://t.co/lkviUKiodJ

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UltimApe@ultimapeover 6 years ago

A good deal of people living in systemic poverty are schizophrenic. I view this whole anti-abortion thing as an attack against people like me. This thread is a protest.

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1/27/2022
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UltimApe@ultimapeover 3 years ago
Replying to @ultimape

How is babby formed?https://t.co/5L4SBL8xPW

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UltimApe@ultimapeabout 5 years ago

Going to fuck with everyone by claiming that I'm against Planned Parenthood and our medical system because they're anti-abortion.https://t.co/MHI0t216Og https://t.co/I1lVzEzoRQ

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1/27/2022
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UltimApe@ultimapeover 3 years ago
Replying to @ultimape

You are all psyop'd. None of you are free of sin.https://t.co/NS7R6OiiEi

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UltimApe@ultimapeabout 5 years ago

This whole space is full of fucked ideas. Stuff that is used to help induce abortions is also super important for having a healthy pregnancy. If you're against abortion medications, you're likely unknowingly against medications that help women have successful births. Its absurd.

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1/27/2022
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UltimApe@ultimapeover 3 years ago
Replying to @ultimape

It's perfectly safe...https://t.co/TWZdaQoS2J

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UltimApe@ultimapeabout 6 years ago

Exogensis or Bust https://t.co/dJAXwULGQK

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1/27/2022
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UltimApe@ultimapeover 3 years ago
Replying to @ultimape

Become ant. They said.https://t.co/YlYx2cCDMP

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UltimApe@ultimapeabout 6 years ago

Ethical Exogenesis or Bust."Who actually gestates [...] the cloned animals? This may be the most serious problem with pet cloning. The cloned dogs and cats don’t simply materialize; they are “grown” in the body of a dog or cat who serves as a surrogate. https://t.co/9wUYMCmOZO

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1/27/2022
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UltimApe@ultimapeover 3 years ago
Replying to @ultimape

Pupate.https://t.co/TorWagHkTv

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UltimApe@ultimapeover 6 years ago

Have we made progress on external gestation? I know we've go that lamb thing we did. I think this is going to be more fundamentally life changing to our species than CRISPR'ing the gene line.We're slowly turning into a species of technological ants.https://t.co/puoo5aJDTJ

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1/27/2022
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UltimApe@ultimapeover 3 years ago
Replying to @ultimape

Did you know that the male hormone booster Nugenix is using an extract from a plant used for centuries to promote lactation?https://t.co/KtdnPvttbG

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UltimApe@ultimapeover 4 years ago

@eigenrobot The world is ruled by expert amatures. You can sell them anything if you can convince them it would help them compete with their mimetic rivals.https://t.co/ckYqy7FGZjWould you care for this Testosterone Supplement I found? https://t.co/Z98rswPCMW

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1/27/2022
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UltimApe@ultimapeover 3 years ago
Replying to @ultimape

Ever wanna figure out how to lay eggs?https://t.co/Z8LndazJHF

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UltimApe@ultimapeover 4 years ago

@__fembot @eigenrobot My ideas haunt me.https://t.co/hmMrYDBV3M

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1/27/2022
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UltimApe@ultimapeover 3 years ago
Replying to @ultimape

This showed up on my YouTube recommendations today."poured a chicken egg into a glass, and put it into a special incubator"https://t.co/CfOvjAatvRhttps://t.co/RVPa3kBb0n

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UltimApe@ultimapeover 4 years ago

For sale: Muridae oocyte, never born."a two-part system that includes incubators, nutrients and a ventilation system. The mouse embryos are placed in glass vials inside incubators, where they float in a special nutrient fluid."https://t.co/tLB90DdyCahttps://t.co/pbtWsOcFb5

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1/27/2022
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UltimApe@ultimapeover 3 years ago
Replying to @ultimape

You can just look this stuff up. No one is stopping you.https://t.co/rYuH1XrAyg

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UltimApe@ultimapeover 4 years ago

I... already know how to make men lactate. Even know the herbs needed."Research has shown that male prolactin levels can also surge, according to a 2008 review on male lactation published in the journal Trends in Ecology and Evolution."https://t.co/2FbThBv5qq

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1/28/2022
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UltimApe@ultimapeabout 3 years ago
Replying to @ultimape

Gotta go fast.https://t.co/5pOp3cbSFs

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UltimApe@ultimapeover 3 years ago

@lemmyhazard We're too slow. Gotta go fast.https://t.co/s3DSWmPxzT

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6/24/2022
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UltimApe@ultimapeabout 3 years ago
Replying to @ultimape

Become dog mum. https://t.co/7S72Z1Olrs

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UltimApe@ultimapeover 3 years ago

"The Dysbiosis of Gut Microbiota (DOGMA) theory has been proposed as a possible explanation of all the observed clinical and pathophysiological features of PCOS." https://t.co/gg8V64ESdX

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6/24/2022
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UltimApe@ultimapealmost 3 years ago
Replying to @ultimape

Fly, you fools."The next step: cajole those induced stem cells to become eggs whose genetic makeup would match that of the patient."https://t.co/fq9KHwkrx8https://t.co/hm7GklBsC6 https://t.co/3wbiOFFhZZ

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UltimApe@ultimapealmost 3 years ago

GATTACA is a good movie. https://t.co/EeNPCS1vZT

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9/18/2022
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UltimApe@ultimapealmost 3 years ago
Replying to @ultimape

My only solace here is that 1) they probably can't actually do that 2) they're not actually starting with pets first and 3) oocyte generation is surprisingly hard.https://t.co/cXv57iY3w0

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UltimApe@ultimapeover 4 years ago

"oh they're adorable animal.And you say, well it's cloned, you know.They went, oh really?Can I do that to my pet?And it flips."https://t.co/GA6K1hO8JRhttps://t.co/JcfDjglKh5 https://t.co/mMZ8tss01P

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9/18/2022
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UltimApe@ultimapealmost 3 years ago
Replying to @ultimape

VCs are likely jumping the gun without knowlege in how this stuff works as they would be salivating over the captive market of*checks notes*the entire human specie.https://t.co/2CsbYOXszM

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9/18/2022
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UltimApe@ultimapealmost 3 years ago
Replying to @ultimape

But at the same time, they seem to be able to do it. I see Sam Altman is a seed funder. Figures. https://t.co/0tYZeYiSMM

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UltimApe@ultimapeabout 7 years ago

"The idea would be to assemble thinkers in robotics, cybernetics, quantum computing, A.I., synthetic biology, genomics, and space travel, as well as philosophers, to discuss the technology and the ethics of human replacement." 👀https://t.co/dnqlWOQLHN

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9/18/2022
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UltimApe@ultimapealmost 3 years ago
Replying to @ultimape

https://t.co/4cu93PahES https://t.co/Jurv7ByfSl

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UltimApe@ultimapeover 6 years ago

I nightmare of futures in which external pregnancy (ectogenisis) is required by law in order to minimize a child's chances of mental disorder; of course that mental disorder is defined by the state.In secret, the military uses that technology to raise clone armies in vats.

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9/18/2022
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UltimApe@ultimapealmost 3 years ago
Replying to @ultimape

Let's see what the bones say about this. https://t.co/pmxxH6I7rJ

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9/18/2022
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UltimApe@ultimapeover 2 years ago
Replying to @ultimape

Reading the bones from 2019 to predict the future."We may one day grow babies outside the womb, but there are many things to consider first"https://t.co/MWjiYEPl5u

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UltimApe@ultimapeover 2 years ago

"Currently, there is no prototype of an artificial womb for humans. And the technology is very much in its infancy. Yet we do need to consider ethical and legal issues before rushing headlong into this reproductive technology."https://t.co/1gk1uq02Oe

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5/19/2023
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UltimApe@ultimapeover 2 years ago
Replying to @ultimape

I'd rather regrow my dog's ovaries than have her cloned.https://t.co/9hYmXAOfFs

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UltimApe@ultimapeover 2 years ago

@vita_dao @longevityprize You guys keep focusing on drugs like that and i'm going to keep on being two steps ahead."mTOR Signaling as a Regulator of Hematopoietic Stem Cell Fate" [2021]https://t.co/HDI6bsRZeOI'm working on regenerating my dog's ovaries.https://t.co/BhejWSLyLi

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5/19/2023