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Guy who tries to advance evolutionary theory by finding god-of-the-gaps reasoning in the field by taking on the perspective of a young earth creationist trying to poke holes using game theory and the work of Thomas Aquinas. https://t.co/9PVz4yPFmN
Oh wait, thats me.I like steelmanning evolutionary biologists that I think are wrong. ITs really funny when I find out an idea is actually something Dawkins brought up in his early work.https://t.co/jh7trTdeZ3
Sorry, but if two ideas in my head conflict, and one stems from Von Neuman's notions on the origin of life and self-replicating systems and one stems from someone making up just-so stories about plausible evolutionary forces to support a world view... https://t.co/sCdkgZDJit
Who's going to win? Some autistic guy who DGAF so is out here making jokes about sonic hedgehog to reference a children's cartoon about evolution and gene splicing, or some curmudgeon who like to bash religion because it gives him high status?Jawsome.https://t.co/s8oerEBV7S https://t.co/cefZkXGI0c
Don't talk to me about cannibalism dad.https://t.co/xHgXiTXjZI
Did you know that some people have mutations that impair the generation of vitamin A from beta carotene?https://t.co/tnogI7PYfeSure would be a shame if a vital component of brain development depended on a copper metabolism related vitamin pathway.
Gosh, if only there was some massively impactful corpus exploring the development of the eye and other complex organs that might be impacted by sonic hedgehog signaling pathways. https://t.co/23xUrqc1pr
the Brain-thoughts Broadcasting Radio be like"muh autism"https://t.co/UQL3RNUf6S
So about that hiccup reflex.https://t.co/eu3MYN24Kk
*hiccups*https://t.co/TlVLSEVS1I
You ever wonder weird thoughts about why drunk people sometimes get hiccups?https://t.co/LxtcBNZ4gL
Or why drunk people get horny and can have seizures?https://t.co/1q0pfcqSTe
"neuropharmacological factors impact thresholds for seizures and sexual climax in similar ways, likely reflecting overall propensity for activation cascades to spread through neuronal networks: thresholds increase with elevated GABA receptor stimulation" https://t.co/tQxid6p4vj
Or why autistic poop makes mice behave autistic and then a gaba related chemical somehow reverses it?https://t.co/FC2QMu3h0H
@dlx5dlx6 @ck_eternity_ @Grimhood @StewartalsopIII I have a similar hunch.Ties between CBD/seizures might be gaba related thru the endocannabinoid's system's impact on it. Also weird ties between taurine and gaba make me think liver/bile involvement. https://t.co/JlnqVicsAkMore notes than sense tho.https://t.co/jUlHinNJy9
*belches*https://t.co/NcfOSYtm6thttps://t.co/TJRnRmtXtY
I wonder how many models of evolution in computer science are riffing off of myths and misunderstandings.Ring species wasn't really even validated until 2012! Allopatric speciation (darwin's finches) might even be a result of collaboration between gut microbes and host!
My, what big gaba producing microbial colonies you have.Why, all the better to combat autistic associated Gerd related belching behavior, my dear.https://t.co/Bs1oj3sO7P
I can pull these ideas out of my ass because you're reading my notebook. 82.7K Tweets worth.Imagine if darwin had google at his disposal? https://t.co/wbco6EWHyc
I'm tempted to grab a sharp knife and start clipping bits of books and threading together a custom zettelkasten. If darwin made his own indexes, why not go one step further and weave the ideas together more directly. A physical xanadu.Pepe_Silvia.jpghttps://t.co/Bs85ShhHlm
Thomas Aquinas and his contemporaries concerned with a thought experiment about what happens to a man's flesh should he be a cannibal but then find god.I merely mused about what would happen if they only ate the stomach.https://t.co/rO37YwwQj8
Tired: lion laid down with the lamb.Wired: Thomas Aquinas treaties on "Whether god wills evils" and his thoughts on lions killing stags.Inspired: this poor little cub, not strong enough to cut thru the stomach, started with the ass and then got stuck.https://t.co/f60woCG3ih
Tired: Neotoenous birdsWired: Paedomorphic dinosaurshttps://t.co/tNS1Jk1xYB
Sharks basically have cloaca. Convergent evolution?https://t.co/tEP325aetH
Evolution can't beat physics."All life on Earth is composed of chiral molecules, and the versions organisms use, either right- or left-handed, determines fundamental properties of their biology."https://t.co/bPm2PQHvI0https://t.co/Wop0GK1mb6
Maybe explains asymetrical sharks?"Bilaterian animals are more or less symmetrical about the midline that divides left and right, but internally most organs are asymmetric in location or shape. How is symmetry broken during development"https://t.co/GOvXKkOyAh
"essentially a genius, who looked at the same facts as others but because of his prodigious powers of creative thinking, he was able to ‘break the set’ of previous assumptions and combine the data into a new and coherent pattern." https://t.co/g78ZSRODzWhttps://t.co/lR4smTbfRf
"Epigenetic modifications may provide a molecular mechanism to Darwin’s ”special difficulty” and explain the emergence of multiple sub-phenotypes among sterile individuals."https://t.co/Ad1wRzvay3https://t.co/GBfkuaecOV
"While the mechanism of response is as yet unclear for most genes, we identified a small subset of genes whose response to microbiome exposure may be regulated by changes in chromatin accessibility."https://t.co/ysQ9tdFS6H https://t.co/4Xbia2DfAD https://t.co/QI4Vjm59Vm
Watching gene edited mice lick themselves like they are the anxious 'pretty ones' in Calhoun's experiments. But they're gene edited/specially breed BALB/c mice whos immune systems don't support right kind of gut microbes to act as viable proxy for real world gut-immune interplay. https://t.co/QKjdM6Oh8t
Don't mind me. Nothing to see here. Not undermining the entire field of genetics to solve my autism.https://t.co/AtnPi4K3oj
These ideas neatly link issues in social parts of the brain https://t.co/NzacDEotHQ and findings that seem to suggest much of autism may be due to brain plasticity issues https://t.co/LRJfrNtZ9VSo the question is, if I have chromatin issues, can I induce plasticity thru diet?
Fuck you I'm a shark."Chromatin organization and global regulation of Hox gene clusters"https://t.co/MnCuNdLAcJhttps://t.co/xifz2bglFC
Hox genes? Flex.https://t.co/6XRU1sC8fx https://t.co/mEJKXPK9rh
Orthologs are neat."We also show convincingly that the horn shark HoxM and HoxN clusters are divergent based on the same characteristics described above and that HoxM is orthologous to the mammalian HoxA cluster, whereas HoxN is an ortholog of HoxD."https://t.co/l9fNobcLXI
A fox in sox hides from the hox in a box.https://t.co/zNwUWz9cEH
Lateral thinking is a hell of a drug.https://t.co/sxXH6mC8xl
I'm just going to keep cracking jokes.https://t.co/45gyfZzHf8
It's an obsession... you see :Phttps://t.co/nOE0wRymVO
Muh vestigial organs. https://t.co/FP2uWlqvgt
Muh horizontal gene transfer.https://t.co/dRH82j7nrN
Muh dysfunctional Metallothionein & Methylation related vitamin A synthesis pathway that emulates a genetic mutation. https://t.co/jSnwYV9evL
I can't make videos about sonic hedgehog on youtube either, but it's because I'm autistic and would want to talk about the role of SHH in autism nonstop for 3 hours straight.https://t.co/F68Mbsv0CRhttps://t.co/FzZigXdeq3
Wish I was joking.Instead, to celebrate the murder of sonic hedgehog, here's a thread on the topic:https://t.co/neriWch8MC