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I went to explore researching sticking yogurt up people's butts and putting the under sun lamps to cure various immune system disorders, and it turned out that John Harvey Kellogg was already doing it in the early 1900s. https://t.co/pggE9lMWRd
He was so far a head of this time, that he was curing seizures via electrocuting vagus nerves. But instead of inserting a sub-dermal device via surgery, he was using electricity and the fact that people's bladders are able to contact it almost directly.
I wish I was joking.Have you considered the idea that high fiber foods improve your microbiome diversity? https://t.co/77wl2IGL14
Learn about the theories of Élie Metchnikoff, Nobel Prize Winner who worked along side Louis Pasteur, in this great talk by @ruairirobertson https://t.co/56tANAJZVmHis ideas are effectively an early version of gut dysbiosis of the a in the 1900s. https://t.co/Lqx3WSLT7I https://t.co/tOPVJ5snTS
Did you know the guy who coined "fight or flight" was very interested in the nature of the vagus nerve and the role it plays in the nature of gut motility?https://t.co/OVAzZrQKZZ
The more eusocial the ant species the more this anti-aging effect seems to occur. I suspect it's because the more they operate with shared-stomachs and collective immune systems, the less their body actually matters. They act more like body cells committing apoptosis when sick.
All sorts of weird stuff happens when you start to add in epigenetic and microbiota into the mix https://t.co/lZivZpB4JL and tie it to immune function.https://t.co/0fuPcPuFsn
It would be funny if all my research ends up circling around aging factors for some reason. Would be funny if immune function and gut microbe health declines with age & age-related diseases, or something like that.https://t.co/VFmFk71kH9
This stuff just falls into my lap. I don't really even have to go out looking for it. Side effect.https://t.co/NEblpe1SBo
Everybody is obsessed about extending life by epigentic factors involved with teleomeres. I'm over here looking at T cells and thinking "why do hibernating animals that shut down their immune function live longer?" and "is this an immune system response driven by gut bacteria?"
Have you ever thought to eat dog food?https://t.co/QCg7yWWLIk
This dog food is like my perfect diet.Its meant to help the dog deal with her skin issues, and improve her poop quality. It even has bacteria from the same strains I am getting thru my diet. Chicken +Huel + Eggs + multivitamins that I found for myself.https://t.co/6XHh1vBBaU https://t.co/WWRTe2Pnnz
"A common question is "coconut water?"Coconut water is not good on keto, 'kay.Still a lot of sugar in that stuff...18 grams... thirty nine in a whole thing;That's basically a soda!... You could also just eat dog food it's usually pretty low carb."https://t.co/Anrjgqc0jy
One of the principle tenants of Keto is low carb, so basically it cuts out most glucose. May have a more direct effect when paired with sources of butyrate, which as I understand is almost always a byproduct of gut bacteria fermentation of fibers.https://t.co/Qc3VBABSKj
That BCP 157 is a A mucus affecting peptide... its possible that Butyrate producing gut bacteria may be acting in a similar way, with huge ties btw many of them and mucus. https://t.co/8fP55q9nZB https://t.co/PvqEPPnwMa
Particularly impactful when there is low glucose! So Keto + Butyrate may be a great combo. "Butyrate specifically modulates MUC gene expression in intestinal epithelial goblet cells deprived of glucose" https://t.co/4bgD5ei3Dj
I've been exploring collagen on the periphery."for reasons which no one understands, ketogenic diets help with a number of central nervous system disorders. So, there may be a keyogenic effect on pain because of the ketosis caused by a low calorie diet."https://t.co/nKBuVOQwmV
I know that collagen and butyrate are tied to the hip https://t.co/w56zd9RCBq, so an expected feature of EDS would be stomach and gastrointesional issues and a general level of vitamin deficiency thru mal-absorption.This would mimic my crohn's disease's imapact.
Interestingly, among people w/ Multiple Sclerosis, a huge percentage of them have bone loss that fits same rough profile of dysfunction as EDS.I got lucky there, my bones are naturally rugged due to longevity genes related to fractures.Did you know bones are mostly collagen?
Bone density weirdness in EDS may be due to similar features as Gauchers Diseaes. I don't know anybody who's been exploring it from that angle tho. Gauchers is a lipid metabolism disorder.IIRC most collagen is processed in a similar manner as lipids as part of digestion.
I'm seeing lots of stuff in papers about vitamin D being low too. That might be caused by poor cholesterol (again, a lipid problem) metabolism, since vitamin D is made literally by a form of cholesterol being irradiated in the skin.https://t.co/hc4QQwU1sj
I made this weird joke about cholesterol. But in looking deeper, Vitamin D3 supplement are made with... get this... a Saponification process involving the rendering of cholesterol from sheep's wool and Irradiating it.https://t.co/gBHIT4xwffhttps://t.co/hSMlLxtnLk
But you didn't hear this from me. I don't really want a nobel prize anyway, imagine the burden of being in the public spotlight!https://t.co/XGdQwDiJTe
I wanna keep researching dexa + vitamin D combo and how they might improve immune & lung function. As well as explore Glucocorticoids impact on bone loss via collagen synthesis (+calcium regulation)e.g. https://t.co/aVN9xCypzpBut am afraid to in public b/c of current events.
For the record, I don't like John Harvey Kellogg. As much as I find his work to be fascinating and way before it's time, I take great umbrage with his dogmatic focus against masturbation.https://t.co/BuSYdn1zc1
I am reminded of 'Planck's Principle', paraphrased as "Science progresses one funeral at a time".But that isn't true. A horrible idea can taint a discourse for a millennia AFAICT. It's idea holding us back from beyond the grave like a kind of memetic strangle hold on truth.
All diets are wrong, some are useful.https://t.co/uwVpHndN7M
More appropriate to say:These diseases often occur when there isn't enough fiber in diet, and western meat eating trends avoid the fibrous material in organ meats (collagen), so there is a lower production of anti-inflammatory SCFAs like butyrate.https://t.co/grcrKwgShC
"These findings are consistent with data that lymphocyte TL dynamics impose a limit on T‐cell proliferation. They suggest that T‐cell lymphopoiesis might stall in individuals with short TL who are infected with SARS‐CoV‐2."https://t.co/wtfEXSTS7Ahuh.https://t.co/95dSACkAu4
Putting on my running shoes.https://t.co/K3vF0WesfE
I saw @Balajis' bio mentions an article about hovarth's clock and methylation."It may be possible to reverse aging. https://t.co/fR9GqB2v2N"I think about this often.https://t.co/mRBOsQh81C
Perhaps a bit too much.https://t.co/ZKOqo7Ebex
Have to tried eating ants?https://t.co/gMSl4VkecXhttps://t.co/OzA53DPw9s
https://t.co/AorhhPC9cH just did an interview about the nature of epigenetic clocks, and how they might not actually be a good measure of Aging in the entirety. It raises similar concerns to my own about their efficacy.https://t.co/k2R7S7Bxgw I derived this insight on my own https://t.co/OFMQlJTMQd
Resveratrol is an antioxidant, and it's likely a main constituent of the grape seeds to help them survive microbiotic and fungal attacks long enough to sprout, and one of many (al)chemical components used to avoid being digested in the stomach.https://t.co/MzkSReBgIr
Fixing my nose and sense of smell so I can find things that please me. Things that smell good.https://t.co/dPRWCvIXMT
Pooh... That's not honey.https://t.co/Yns8zKUN6v
What happens if you give someone that drug that rejuvenates their "epigenetic clock", and then use an FMT to give the microbes in theri gut to a mouse. Does the mouse get younger?Many "diabetic drugs" are eaten by gut microbes if taken orally...
Is it reverse psychology if I politely imply that Freud's theories on masturbation are junk, and he can go fuck himself? 😝 https://t.co/WGmjK9sb5c
Did you know that Swedish people live long and they have a special yogurt called "Filmjölk" which is similar to Norway's "Surmjølk".https://t.co/wWrnTDGjNh
I wonder if they eat Surströmming."Health expert Henrik Ennart didn't have a simple answer to explain Vittsjö's aged population, but explained that old age can often be attributed to dietary habits."https://t.co/bWCyRb8oUA
"These bacteria produce carbon dioxide and a number of compounds that account for the unique odour: pungent (propionic acid), rotten-egg (hydrogen sulfide), rancid-butter (butyric acid), and vinegary (acetic acid)"https://t.co/kdvacJllKUSounds Delicioushttps://t.co/VGq4IiWZjH
Ya'll ever look up SIRT-1 and realize you've been exploring those pathways indirectly while trying to fix age-related diseases tied intimately to the gut and immune function?No? Just me? Well then.https://t.co/UfzoVUBahS
@SimonDeDeo @ElysiumHQ I'm going to live forever by drinking red wine and eating collagen peptides that ferment by gut bacteria into butyrate, which activate SIRT-1 to downregulate the inflammation in my gut and help me maintain mitochondrial function, lol. https://t.co/yfXrjEcQZk
Vitamin C production by milk-souring bacteria is likely no longer on your food labels if you live in the states.https://t.co/oluYToa9r6
I accidentally a funny.https://t.co/mgLAaocyXdhttps://t.co/jUpWpRr8OB https://t.co/KrJkmOVp3Q
I can't tell how much vitamin C is in my kefir, but I bet there's enough to knock out any phytochemicals that might be impacting the gut bacteria I want in my gut.https://t.co/plopOPYw13
He invented a machine that pumped yogurt into people's rectums. 😂> Dr. Kellogg believed that the bacteria used to make yogurt were protective against disease and “should be planted where they are most needed and may render the most effective service.” https://t.co/LZcTCSSMdV
It's amazing how right and wrong someone could be at the same time.https://t.co/DznXDu5TlR
If we assume that the population of people Kellogg was studying had some kind of serotonin imbalance leading to constipation (like I seem to have). It makes more sense that he was sticking yogurt (probiotics) up peoples butts, and obsessed with vagal stimulation and sunlight.
Somehow the thread you'e reading is turning into a repository about both undermining and enhancing turn-of-the-century ideas about masturbation and microbiota.I really hate that western science & psychological history has tied the two together.https://t.co/M6iBSgk9D9
Why am I looking up Pica behaviors in autistic mice?https://t.co/rYUYu5heKrWhy am reading about DH lawerence's ideas on masturbation?https://t.co/um4dr9uWJULets just say that I wanna figure out that weird grooming behavior is in Calhoun's studies.https://t.co/bqr3FigdeP
I wanna use Quantified Self techniques to track how often I masturbate/have sex, to see if there are correlations w/ intestinal pain or other weird issues I may be unaware of consciously. But I think it'd be framed as perverted to say this in public.https://t.co/s00bSS2rHg
So instead, I'll allude to it via weird things having to do with male vitality and the impacts of diabetes and immune function on sexual health.https://t.co/5q27xrKus3
Hey, at least I don't want to raise the dead like some kind of medieval necromancer digging up grave sites to get around taboos on learning about the human body.https://t.co/PWlVBwbUNM
If only doctors could prescribe a diet to to help, instead of hocking probiotics like candy.https://t.co/yDoYGBvWZT
Be sure to drink your Ovaltine, it's got what gut's crave.https://t.co/jMPcPI7aTH
Protein can act as an alternate nitrogen source vs fiber, and butyrate from plant fiber? There is more than one way to eat fermented cat skin.https://t.co/CigBZTqIUt
Tired: Getting SCFAs by fermenting various plant matter.Wired: Eating stinky fish.https://t.co/1nrmLzbicU
Huh.Estrogen and Resveratrol impact SIRT1 expression and modulate vascular smooth muscle tissue. https://t.co/zNUUqcKXYQWhich plays a role in heart disease.https://t.co/77ivJuxt9BVia microbiota?https://t.co/08XGaqOXjJ
An entire line of probiotics is basically a round-about way of getting the impact of cranberry seeds in your butt and driving mucus production (so you don't digest them).https://t.co/3yBzWuTb5V
A paper on Metchnikoff's work was surfaced on HackerNews"Elie Metchnikoff, the Man and the Myth"https://t.co/hUp0sEhHhY
Thinking a lot about how these results might depend heavily on diet.https://t.co/VFIf0UlmW7
So many studies blindly parrot the idea that high fiber vegetables contribute to health.They ignore that fermented fishes and meats reproduce the same chemistry.Butyrate named after the smell of butter! It's dumb.https://t.co/m73VLErbuu https://t.co/Ot254KARNG
"These bacteria produce carbon dioxide and a number of compounds that account for the unique odour: pungent (propionic acid), rotten-egg (hydrogen sulfide), rancid-butter (butyric acid), and vinegary (acetic acid)"https://t.co/kdvacJllKUSounds Delicioushttps://t.co/VGq4IiWZjH
I am told women are fascinated by cheese.https://t.co/6pWbL0uqsC
@mchapiro I can literally smell my own self change when I am in ketosis. I start leaking chemicals trapped in my body fat and it changes my arm pit smell. After a couple of weeks my skin starts smelling of cheese (antiinflammatory butryate/propinate producing bacteria)
Bug chitin ferments into butyrate too. Everyone forgets that chitin is in fungus *AND* insects.Yum!https://t.co/0Af1L5rE6O https://t.co/blOKRuHCJ0
Medical Experts paraded around by media:"EAT MORE FIBER"Me:*investigates every potential bacterial and fungal nitrogen source that might be helping promote butyrate to fix crohn's related inflammation*Them: Not like that!!! https://t.co/KRdciOgnRQ
I'm eating @jiminysforpets and the house's dog is mad at me."Cricket protein powder combined with oats, quinoa, sweet potato and other plant-based ingredients creates a nutrient dense and delicious dog food."https://t.co/4CxrTgeqnaGotta gut health!https://t.co/WSVp6xw0IA
Cricket is one of the few urban producible proteins. If you pair up w/ microgreens, it can hypothetically cut out more fuel use vs large scale industrial farming of plants. Cricket frass is like like rabbit poop: it doesn't heat up composting. Very similar to vermicomposting.
If you don't like the idea of eating insects, you can also breed them as a fairly easy source of proteins for chickens.https://t.co/lxNOjfcELX
You'll wanna pay attention to a process called "Gut loading", where you pre-fill the cricket with other nutritious substances. They also smell bad.Lots of great resources on feeding 'herps' that can be expanded upon.https://t.co/uzTbQk3K2F
If you have a significantly large colony of them, you'll want to investigate rat and mouse proofing the area. As you might imagine, housing insects in your own house will also be an opportunity for other insects to take up residence. Don't accidentally attract roaches!
You may think I'm trolling vegans with this thread you're reading. But actually I'm trolling the raw meat diet people by showcasing how eating fiber from cereals might actually be fine if their guts weren't so weak. 😈https://t.co/ouxILdc9k5
I actually think a raw food diet ought to work really well, but something odd is happening with how my body reabsorbs bile. Or rather how it doesn't. And that is tied weirdness for both plant and animal diets.Shit posting+trolling how I invent ideas.https://t.co/w6ekHSiM2d
Does anyone know how to test stomach acid levels without vomiting? Those I ask would rather not."Together these results highlight the importance of including measurements of gastric pH when investigating gut microbial dynamics within and across species."https://t.co/HtWg6evMDA
Would be really funny of 'ancestral diets' actually included bread and grains to a great degree, and people masturbating's about meat based diets don't realize they're actually seeing the result of industrialized food practices absolutely butchering our food's dietary profile.
Chaserhttps://t.co/BNUgJGlddf
"however, we instead imagine the people naked, feasting on berries, without shelter, and without social differentiation. The contemporary imagination of the state of nature has been bounded by the thought experiments of Western political theorists. "https://t.co/Ctk0EWX6vm
Watching everyone around me age while my own body goes in reverse. Its wild.All the people I care about are dying, and no one listens to me.https://t.co/rVnpsGvtdn
"Abnormal shifts in the gut microbiome, however, have been implicated in the pathogenesis of age-related chronic diseases, including obesity, cardiovascular diseases and neurodegenerative diseases. [...] emerging as a key factor in the aging process."https://t.co/8pOrQElB7L
This isn't even my final form.https://t.co/kL0Dj95K04
I'm eating chocolate.https://t.co/YEK4AaWGMc
Earlier today I soaked some round animals in cow lipids and spread some rock crystals and sour tasting fast mimicking spices on them.https://t.co/ZlfupEdcVZ
One reason Hershey's taste so much different from UK chocolates is Hershey's milk was once slightly fermented, has way less actual cocoa, & way more sugar.https://t.co/VliWP3hVjCInterestingly, Hershey's stopped sour milk & just adds butyratic acid now?https://t.co/wO5R5QOYuq
Thinking a lot about mixing sea salt, cumin and chocolate together right now.https://t.co/6A8O2eru5uhttps://t.co/6PijcTSAdu
You haven't lived until you mixed Apple and Shepard's Pie. This is the only reason you would want to substitute cumin with cinnamon when making something akin to pumpkin spice.Cumin, nutmeg, ginger, clove, cardamum, tumeric, mace, and allspice.https://t.co/O6N7GHr9rD
cuminaldehyde is also in roast beef, cognac, and sherry?What kind of cinnamon has the highest amounts of cinnamic acid?Also why does this book cost $84? https://t.co/WhUoWHAIS4 https://t.co/myNIx5eASL
Wat"other products that we're looking for from that wood are going to be some of the breakdown products from the oak itself. As it breaks down the wood starts to give some vanilla aromas and some cinnamon. Which if you think in terms of apple pie..."https://t.co/NylimUpqEM
Benzaldehydes, not even once.https://t.co/FJVykCwdrm
Its wild how many chemicals in aged drinks end up just being something dissolved out of old trees.https://t.co/RNcpRXXDJwhttps://t.co/Phc1vyCZzK
Cinnamon is now a dog, because it bark."Cinnamon is a spice obtained from the inner bark of several tree species from the genus Cinnamomum." https://t.co/U3jttTdicFBark woof barkhttps://t.co/9FBaLBizk6
Butter is a soup if you put enough spices in it.https://t.co/Q4CTQ6BpDd
Castor Oil does WHAT?https://t.co/c1UR3Rcybr https://t.co/gOWul157Ca
"This review builds upon the foundation of Nobel Prize winner Élie Metchnikoff’s research on immunology. Metchnikoff is revered for first discovering the connection between immunity and probiotic fermented milk products, such as kefir, over 100 years ago." https://t.co/cHdinqljUC
"Kefir can act as an anti-inflammatory agent by reducing expression of IL-6, IL-1, TNF-α, and interferon-γ. Hence, kefir might be a significant inhibitor of the ‘cytokine storm’ that contributes to COVID-19."https://t.co/TkHyiyIVcN
"More recently, increased microglial activation in somatosensory cortex (as evaluated through 11C-PK11195 binding) was associated with higher plasma levels of IL-1β, IL-6, IL-8, and TNF-α in premanifest HD gene carriers"https://t.co/ZBdJjkikvMHuh.https://t.co/8bPlpd6avb
Castor Oil.=>2022 ICD-10-CM Diagnosis Code R11.13 Vomiting of fecal matterhttps://t.co/6rX9qwCTwd
I have no idea what I'm doing.https://t.co/8fKGelpB3Q
I am a fool, you see.https://t.co/cgT6MCA3L6
I am not a doctor. https://t.co/i7Zvw3ojUf
"We found evidence for multiple mechanisms that we know are linked to PD, but we didn’t know they were happening in the gut also and are orchestrated by the microbiome" [December 1, 2022]https://t.co/YdZhfjeyqV🤔🤫😇https://t.co/qWUdOUttHr
A fool's wisdom is hard won.https://t.co/p11TGlNurp
"How would a fool do it?"https://t.co/6gwP9ZEPDJ
We could return.https://t.co/eA6H61qQe2
@LagrangianBoink @SamoBurja @wolftivy @TylerAlterman @rivatez Lets fuckin gooo..."The early texts indicate that Sumerian butter and cheese were made from soured milk (Stol 1993: 101). The butter was churned in earthenware" https://t.co/7GgCkdEC9k https://t.co/wq0WOAb3Lq
Turn back the clock.Study on epigentic aging clocks seems to suggest the old one don't capture age related cognition changes well. https://t.co/Hm6dQn0dD2