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#TMMTO the impact of oxytocin (driven via gut-brain axis) and it's impact in the brain as an antiinflammatory.Heh. https://t.co/ubNiE9cK89
"shows for the first time that brain inflammation is significantly elevated - more than 30 per cent higher - in people with obsessive-compulsive disorder (OCD) than in people without the condition."https://t.co/648Tkr5irJ
"Hypocrite that you are, for you trust the chemicals in your brain to tell you they are chemicals."https://t.co/qHkBz5Vu8W
"The associations between baseline oxytocin and OCD severity and between oxytocin changes and treatment response support the notions that oxytocin is involved in OCD pathophysiology,"https://t.co/VeJC5W0nRCVia serotonin.https://t.co/Y6DPLUJFu5
Visceral Hallucinations as Symptom of OCD?"One of my patients, [...] was referred to me after visiting medical doctors (including urologists) to determine the cause of his urge to repeatedly empty his bladder throughout the day and also during the night"https://t.co/bBALZUPt2M
I wonder how often OCD is actually a form of hallucinations.https://t.co/K1MdcBUuOC
I wish we knew more about SSRIs and other serotonin regulation mechanisms impact stuff in OCD and itch. I think something is there that seems to coincide w/ my own biology. Sometimes I can't stop itching & thinking about them once surprised by an insect.https://t.co/7AgcbT91LS
Smells Salvia divinorum. Metaphorically speaking.Ties between anxiety and dynorphin / kappa-opioid problems linked to OCD."The animal model findings point to a potential role of kappa opioid systems in hastening the pathogenesis of OCD" [2019]https://t.co/H8NPqP0wWN
Why does D2/D3 dopamine agonism impact kappa-opioid receptor? hmm.https://t.co/6nEhELqpY9
Whelp. I guess I can't rule that out anymore.https://t.co/WyZ4LBmtB4
Oddly, this many SSRIs doesn't work for OCDBut one that do (Clomipramine) block SERT.So mutations in SLC6A4 may be more of a factor than generalized mutations in serotonin receptors.https://t.co/pyrVvY9ZNp
Amitriptyline HCl -> Serotonin /norepinephrine receptor/5-HT4/5-HT2 inhibitor"Antidepressants can treat inflammatory bowel disease through regulation of the nuclear factor-κB/nitric oxide pathway and inhibition of cytokine production: A hypothesis"https://t.co/bKxjjq9CEz
Squeek."Although side effects of fluoxetine or L. rhamnosus on androgen-dependent behaviors could not be demonstrated, L. rhamnosus treatment appeared comparable to fluoxetine treatment in attenuating mouse OCD-like behaviors."https://t.co/SWITLm3Pyfhttps://t.co/HGex6OGILu
"New research indicates that some patients [...] who do not respond to standard treatment or whose symptoms worsen with these medications, may have a form of autoimmune encephalitis, known as basal ganglia encephalitis, prompting their OCD-like behaviors."https://t.co/n4D2PIzYhG
Huh."This anxiety can worsen dramatically in the weeks and months after delivery and takes the form of obsessive compulsive disorder (OCD)." https://t.co/rJWTw8LZo7https://t.co/ApChkUsPlA
Wat"OCD was significantly correlated with a higher [Kurtzke Expanded Disability Status Scale] scoreOCD might be considered in quantifying disability of patients with MS. It might be suggested that all the patients with MS to be screened for OCD."https://t.co/xXVnr7GULn