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🧵 Thread (134 tweets)

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UltimApe@ultimape• over 5 years ago

I found a paper about micro-droplet condensates within a cell acting as a molecular Schelling point to help create rapid responses of protein development. https://t.co/GzNjEbsWgo https://t.co/RjVyOofN15

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5/18/2020
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UltimApe@ultimape• over 5 years ago
Replying to @ultimape

It mingled in my head with all the investigations I've been doing about viral particles and droplets.https://t.co/MdWqHolPM5

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5/18/2020
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UltimApe@ultimape• over 5 years ago
Replying to @ultimape

Thinking about moths.https://t.co/vjF939Obq0

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UltimApe@ultimape• over 5 years ago

"When infected by a virus known as baculovirus, gypsy moth caterpillars mysteriously climb for the treetops. They then die and scatter viral particles, infecting their comrades below."https://t.co/Mb3w6NOzuTFlu viruses, in my rainforest caterpillar? 🐛https://t.co/5ux8wLj0xA

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5/18/2020
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UltimApe@ultimape• over 5 years ago
Replying to @ultimape

About sneezing trees.https://t.co/76mY2SbUXF

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UltimApe@ultimape• over 5 years ago

"You can smell the defense chemistry of a forest under attack. Something is being emitted and plants and animals perceive that and change their behaviors."https://t.co/r9IWeZVMoxPinene affects actylecholine by downregulating a thing that metabolizes it. Changes behavior.

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5/18/2020
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UltimApe@ultimape• over 5 years ago
Replying to @ultimape

So long story short, a tree's lungs are it's leaves, and they can sneeze out viruses in droplets of dew.https://t.co/ujqTbs2YSc

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5/18/2020
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UltimApe@ultimape• over 5 years ago
Replying to @ultimape

"The air that we breathe is chock-full of particles called aerosols. These tiny liquid or solid particles come from hundreds of sources including trees [...] The small particles influence cloud formation and rainfall, and affect climate and human health."https://t.co/WE7cn4vBGz

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5/18/2020
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UltimApe@ultimape• over 5 years ago
Replying to @ultimape

Horror story: Bats hanging on trees, shitting on leaves, thus leveraging leaf based viral aresoles to spread fecal borne illness.It doesn't have to infect the plant to have the plant spread it. 🤔But all the studies assume that.https://t.co/KN7tmj8Sbx

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5/18/2020
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UltimApe@ultimape• over 5 years ago
Replying to @ultimape

Assumptionshttps://t.co/qP8F6fUyhg

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UltimApe@ultimape• about 7 years ago

"A zebra doesn't have to outrun the lion, just the slowest member of the herd""I conclude that a clear evolutionary approach to the problem of host-pathogen interactions might encourage the field to reconsider some of its most closely held tenets."https://t.co/Nu0XvcLERy

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5/18/2020
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UltimApe@ultimape• over 5 years ago
Replying to @ultimape

Do bats eat moths?Do moths eat plants?Why does caterpillar poop disable corn anti-parasite defenses?https://t.co/USuI26UpXL

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5/18/2020
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UltimApe@ultimape• over 5 years ago
Replying to @ultimape

It seems to me that plants would be trying to infect other plants, and harbor bats that eat moths while simultaneously trying to get the moth to find a different host to parasite off.

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5/18/2020
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UltimApe@ultimape• over 5 years ago
Replying to @ultimape

"A team of German and French scientists has been able to show that one particular class of plant toxins slows down the development of competing plants by specifically acting on the structure of their genome."https://t.co/HuSd9Shc1x

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5/18/2020
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UltimApe@ultimape• over 5 years ago
Replying to @ultimape

Tired: The Happening.Wired: The Pulse.Inspired: Koyaanisqatsi, Powaqqatsi, and Naqoyqatsi https://t.co/hlROqlFskIhttps://t.co/izx7Wmqt8D

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UltimApe@ultimape• over 5 years ago

"the pulsing flow of freeway and street traffic pumping packets of human energy encased in automobiles into cities and other urban clusters are virtually identical, when sped up, to the pulsing flow of blood coursing through the arteries"https://t.co/q2QZluu5Nh

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5/18/2020
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UltimApe@ultimape• over 5 years ago
Replying to @ultimape

Man made landscapes stemming back to the bronze agecollapse.https://t.co/jM45Mk0krg

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5/18/2020
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UltimApe@ultimape• over 5 years ago
Replying to @ultimape

I'm going to be buying a bunch of indoor gardening equipment with my next paycheck. I wanna grow plants that induce abortions.Stuff that smells good and has funny taste'ing roots.Molesting plants to make them long and hardy.https://t.co/PzS5m649NQ https://t.co/5U4DQkrFSj

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5/18/2020
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UltimApe@ultimape• over 5 years ago
Replying to @ultimape

A plant's root system is an inside out stomach, and it's leaves are inside out lungs. So of course a plant's roots are going to house a microbial/viral/fungal ecosystem that persists thru generations.https://t.co/gglZoX9bxw

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UltimApe@ultimape• almost 6 years ago

I'm taking black cohosh because I read it induces abortions, affects menopause, and might make some people's balls shrink.Mine got bigger! I wonder if Japanese raccoon dogs hibernate. https://t.co/95xaOrjBBU

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5/18/2020
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UltimApe@ultimape• over 5 years ago
Replying to @ultimape

Apparently some scientists figured out you can trigger herbivore responses in Alder by using a hole punch. It changes the nutrient density in leaves, causing them to decompose faster.https://t.co/0y3rUJ1956

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5/18/2020
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UltimApe@ultimape• over 5 years ago
Replying to @ultimape

Cool thread exploring bees being jerks to plants.https://t.co/HZJkyl8Atd

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5/22/2020
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UltimApe@ultimape• over 5 years ago
Replying to @ultimape

Headcannon: Bees are happy to be the plant's sex toys. But if the plants stop ejaculating pollen on them, they start turning into leaf sadists. Thankfully, the biting turns the plants on and makes them want to be toy'ed with again.https://t.co/vGlozVJPBh

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UltimApe@ultimape• over 7 years ago

Ant plant mutualisms are quite erotic TBH.https://t.co/iBUsMqLhPa

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5/22/2020
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UltimApe@ultimape• over 5 years ago
Replying to @ultimape

I suspect this kind of kinky plant foreplay occurs in much of the insect->plant interactions around pollination.https://t.co/oaYegKdI7D

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UltimApe@ultimape• over 8 years ago

Happy Saturday.This plant covers flies toys with viscous sex juices. It then abuses ants to spread it's progeny...https://t.co/7wO04YC3RP

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5/22/2020
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UltimApe@ultimape• over 5 years ago
Replying to @ultimape

I wonder if the biting behavior happens more often for the flowers that produce caffeine.https://t.co/w3WsrVtY4b

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UltimApe@ultimape• about 9 years ago

Bees are driven to caffine producing flowers thru manipulation of dopamine: https://t.co/qkYTWgEtzg

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5/22/2020
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UltimApe@ultimape• over 5 years ago
Replying to @ultimape

"The findings suggest that plants use caffeine to “trick” bees into visiting lower quality food sources."https://t.co/NwJwYzPlur

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5/22/2020
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UltimApe@ultimape• over 5 years ago
Replying to @ultimape

"The effect of caffeine on the bees' long-term memory was profound with three times as many bees remembering the floral scent 24 hours later and twice as many bees remembering the scent after three days."https://t.co/xYrxOk2hyQ

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5/22/2020
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UltimApe@ultimape• over 5 years ago
Replying to @ultimape

If the plant abuses the bees to much without putting out pollen, the bees start biting the flower itself to get at it's caffeine.Or as BeeFreud would say, "this oral fixation reminds the bees of biting their way out of the cocoon."https://t.co/GNecLbUGyj https://t.co/x158k6TNyp

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UltimApe@ultimape• over 8 years ago

Video about 'Nectar Robbing' -> https://t.co/FiHLhuVpKHInterestingly, happens more aggressively if flowers try to trick bees with caffeine.

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5/22/2020
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UltimApe@ultimape• over 5 years ago
Replying to @ultimape

So the bees that bite on leaves are a sort of anxiety induced transference, likely driven by changes in their gut microbes?I bet a bee's gut microbes really love caffeine.https://t.co/wc6aGgj6dg

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5/22/2020
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UltimApe@ultimape• over 5 years ago
Replying to @ultimape

A plant's sexual organs are just hanging out in the air. Then a bee comes along and starts vibrating violently and a whole bunch of pollen gushes out.https://t.co/edOKtfkSIr

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UltimApe@ultimape• over 5 years ago

A plant's root system is an inside out stomach, and it's leaves are inside out lungs. So of course a plant's roots are going to house a microbial/viral/fungal ecosystem that persists thru generations.https://t.co/gglZoX9bxw

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5/22/2020
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UltimApe@ultimape• over 5 years ago
Replying to @ultimape

I'm sorry, the scientific term for bees masturbating flowers is actually 'sonicating'. Using medicalized terms makes it less vulgar."Here is some footage of Bombus impatiens sonicating a large Senna flower"https://t.co/yCxfGZI9ZL

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5/22/2020
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UltimApe@ultimape• over 5 years ago
Replying to @ultimape

Stroking and fingering plant sex organs can be done by humans too.https://t.co/kHLSEp9THd

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5/22/2020
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UltimApe@ultimape• over 5 years ago
Replying to @ultimape

Strictly speaking, sonication isn't actually the same as masturbation. It is about applying energy thru sound waves.TIL: This can be used to rip the tails off of rat semen so they can be put thru various filtering and assaying equipment without clogging.

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5/22/2020
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UltimApe@ultimape• over 5 years ago
Replying to @ultimape

And now,somehow,thru a reference to Flow Cytometry,I am found,circling around,to exploration of Cellular Machinery.https://t.co/zaD6KI3Oyz

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5/22/2020
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UltimApe@ultimape• over 5 years ago
Replying to @ultimape

Since Flow Cytometry works for semen, surely UwU must do it for pollen?OwO, what's this?'The rising world of flow cytometric analysis of pollen grains' [2015]https://t.co/Mq8fZd2OFz

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5/22/2020
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UltimApe@ultimape• over 5 years ago
Replying to @ultimape

Apparently Reactive Oxygen Species causing pollen to be infertile are also an issue if you heat up the plant sex organs too much.'Direct analysis of pollen fitness by flow cytometry: implications for pollen response to stress' [2019]https://t.co/hpvQX7i5nf

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5/22/2020
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UltimApe@ultimape• over 5 years ago
Replying to @ultimape

I'd bet there is a moth like insect that spreads a deadly disease in this area:"There are also legends about butterflies in Kochi Prefecture (among others) causing sickness and death, and swarming and suffocating individuals walking in the evening."https://t.co/ejBxgFNpyG

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UltimApe@ultimape• over 5 years ago

"beautiful visualization and reminder of just how much Phos has changed and, especially when put in conjunction with the next meaning (the spirits of the dead, an incarnation of the soul, the immortal soul), drives home exactly what has caused this change"https://t.co/iSAF5vnAMw

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5/25/2020
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UltimApe@ultimape• over 5 years ago
Replying to @ultimape

After reading what I have about the nature of viral particulates and other sub PM2.5 materials, I am thinking that I should just stop breathing. I think its the only safe way to avoid being infected. /shttps://t.co/LQ1YvHG00Q

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UltimApe@ultimape• over 6 years ago

Collecting in clouds, recombining themselves as enough of their latent molecular mass congregate on the surface or in the air. Viruses self forming and falling out of the sky.https://t.co/U9jlNGyzWW

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5/27/2020
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UltimApe@ultimape• over 5 years ago
Replying to @ultimape

Don't mind me, just exploring history of inoculation, variolation, FMT, and the concept of immunity as a way to explore the history of health and disease norms, as a way to better understand how past societies dealt with diseases of the immune system.https://t.co/qLPYqEgI2f

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UltimApe@ultimape• about 6 years ago

"The vast majority of dogs won’t eat feces that are more than two days old, suggesting that they prefer the fresh stuff for its microbial punch, she says, especially when they’re attempting to regenerate their own gut flora."https://t.co/MQ4AgRlIr8

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5/27/2020
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UltimApe@ultimape• over 5 years ago
Replying to @ultimape

I learn more from veterinarian science than I do from human science. People will just go and cut a hole in the side of a cow so we can shove bacteria in them.We also pull bacteria out & use calf stomach enzymes to make cheese.Dairy farming is intense.https://t.co/QVXDQ7qAPS

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UltimApe@ultimape• over 5 years ago

WTF"to treat simple indigestion of dairy cattle. Transfaunation refers to transferring a broad spectrum of micro-organisms including bacteria, protozoa, fungi and archaea from the rumen of a healthy donor animal to the rumen of a sick recipient animal"https://t.co/2OPf87eoqd

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5/27/2020
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UltimApe@ultimape• over 5 years ago
Replying to @ultimape

I suspect one day you'll be able to go to the local pharmacy and buy brown Mentos.Only the freshest brands will be able to pull off this purity/disgust inversion and have the cultural lineage to transition back into medicinal branding.https://t.co/IhHkrHxXyX https://t.co/Q1fHeucfpc

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5/27/2020
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UltimApe@ultimape• over 5 years ago
Replying to @ultimape

I'm going to go eat some cheese and cry a bit in side. https://t.co/FJPxoNA0CU

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5/27/2020
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UltimApe@ultimape• over 5 years ago
Replying to @ultimape

I am getting calcium in my diet so that I don't have to eat baby poop when I am older.https://t.co/OFuU4VPibL

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UltimApe@ultimape• over 5 years ago

Making a joke about wanting to learn how to set my own bones, and then some time shortly later I am learning about a traditional Korean health aid that is suspected to speed bone break recovery.https://t.co/IFWL8xAg29

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5/27/2020
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UltimApe@ultimape• over 5 years ago
Replying to @ultimape

One of the more fascinating things is that FMT seems to occasionally reverse certain kinds of hair loss.It would be interesting if its the same kind of hair loss that we see in schizophrenia. https://t.co/sMICB75b2u

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5/27/2020
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UltimApe@ultimape• about 5 years ago
Replying to @ultimape

Bustin makes me feel good. A little hit of Oxy(tocin). Ah yeah.https://t.co/LSWVzJnvq1

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UltimApe@ultimape• over 6 years ago

Viruses CRISPRing themselves to pieces to disperse themselves into the ĂŚther.https://t.co/ISGEuXWQ11https://t.co/cJGLI63aw7

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7/6/2020
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UltimApe@ultimape• about 5 years ago
Replying to @ultimape

Don't worry, all of the things I write are stories for children.https://t.co/25H5LmcsEu

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UltimApe@ultimape• about 5 years ago

Bust'n makes me feel good.https://t.co/reoRSI48gRCivilizational collapse via narrative wireheading. Let me tell you something...https://t.co/TWZdaQoS2J

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7/6/2020
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UltimApe@ultimape• about 5 years ago
Replying to @ultimape

https://t.co/0dU77hB5vB [1 July 2012]https://t.co/XlqVw7hEU6 [March 2017]https://t.co/DjvZPOEgJT [July 15, 2020]So eating omega 3s seems to lessen impact of pollution associated lung damage.https://t.co/L0PtBxYaKN

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UltimApe@ultimape• over 5 years ago

Air pollution -> T Cellshttps://t.co/pMly6TP8BsMasks for pollution -> V Blood Pressurehttps://t.co/7jf7fCHdTvCD8+ T Cells -> ^ High Blood Pressurehttps://t.co/Kd5njBl22Q"CD8+ T cells [predominant] in human MS lesions"https://t.co/Ovs6G7687Uhttps://t.co/DSsTTEDFHO

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7/17/2020
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UltimApe@ultimape• about 5 years ago
Replying to @ultimape

How odd; eating a prebiotic that boosts serotonin production in gut bacteria and the brain seems to improve our response to pollution?https://t.co/Ljky6cmvYG [February 2015]https://t.co/YnRr15fNEl [2018 Jun]https://t.co/wDjefIqaQ0 [11 September 2017]https://t.co/ujBCbRkQ0P

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UltimApe@ultimape• about 6 years ago

"A randomised controlled trial of vitamin D and omega-3 long chain polyunsaturated fatty acids in the treatment of irritability and hyperactivity among children with autism spectrum disorder"https://t.co/E360Ea2rVmhttps://t.co/T9SEecF0GO

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7/17/2020
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UltimApe@ultimape• about 5 years ago
Replying to @ultimape

Thinking a lot about how FDA regulations require alcohols to be neutered with sulfur dioxide to meet alcohol % guidelines, and how that might be killing lactic acid bacteria in our gut.https://t.co/1ERS3dgPDt

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UltimApe@ultimape• over 5 years ago

@GRITCULT Show me a city where people aren't dying from suicide, and I'll show you a city where people eat well and aren't on SSRIs to compensate for poor trypophan->serotonin production in their gut.

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7/17/2020
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UltimApe@ultimape• about 5 years ago
Replying to @ultimape

A group is experimenting with using a-pinene as a way to prevent wine from becoming too alcoholic.https://t.co/Azj6ScjKvf

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7/17/2020
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UltimApe@ultimape• about 5 years ago
Replying to @ultimape

That might be digestible by Lactic Acid Bacteria; It was shone that they can literally metabolize (and produce) terpenes.https://t.co/ses8IVyDZS

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7/17/2020
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UltimApe@ultimape• about 5 years ago
Replying to @ultimape

"The gut microbiota: a major player in the toxicity of environmental pollutants?" [04 May 2016]https://t.co/069MCzUsE7So fucking with these bacteria might be a bad idea.

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7/17/2020
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UltimApe@ultimape• about 5 years ago
Replying to @ultimape

I hate this so much"The toxicity of sulphur dioxide towards certain lactic acid bacteria from fermented apple juice" [1976 Apr]https://t.co/WxDnfllBJS

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7/17/2020
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UltimApe@ultimape• about 5 years ago
Replying to @ultimape

Heaven forbid we get some commensual lactic acid bacteria in our gut."Inhibition of certain lactic acid bacteria by free and bound sulphur dioxide" [December 1963]https://t.co/TwjVeARyPR

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7/17/2020
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UltimApe@ultimape• about 5 years ago
Replying to @ultimape

Oh no, our food is going to go bad. Lets destroy our gut microbiome so we can preserve it."Effects of SO2 on lactic acid bacteria physiology when used as a preservative compound in malolactic fermentation" [23 May 2012]https://t.co/Lm8qjfqmHV

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7/17/2020
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UltimApe@ultimape• about 5 years ago
Replying to @ultimape

We're fucking dumb."Hydrogen sulfide toxicity in the gut environment: Meta-analysis of sulfate-reducing and lactic acid bacteria in inflammatory processes" [17 March 2020]https://t.co/xV9tf96BlOhttps://t.co/ciEFxucixK https://t.co/8aOnIHZl6C

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UltimApe@ultimape• about 5 years ago

Learn about the theories of Élie Metchnikoff, Nobel Prize Winner who worked along side Louis Pasteur, in this great talk by @ruairirobertson https://t.co/56tANAJZVmHis ideas are effectively an early version of gut dysbiosis of the a in the 1900s. https://t.co/Lqx3WSLT7I https://t.co/tOPVJ5snTS

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7/17/2020
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UltimApe@ultimape• about 5 years ago
Replying to @ultimape

"The new wine is dying on the vineHow much must you age before you're ageless?Align yourself with the divineAllow your inner sage to burn you rage less" 🎶https://t.co/3Tx2QyR32P

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7/17/2020
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UltimApe@ultimape• about 5 years ago
Replying to @ultimape

Reap what you sow.Weeping in your soul."Air pollution exposure is associated with the gut microbiome as revealed by shotgun metagenomic sequencing" [May 2020]https://t.co/cZAUBRwn6Y

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7/17/2020
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UltimApe@ultimape• about 5 years ago
Replying to @ultimape

One of my goals in life is to have @garyvee follow me because I know more about wine than he does. https://t.co/zhgjVxtgv6

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UltimApe@ultimape• about 7 years ago

It's been fun to see wine centers in stores grow in popularity. Seeing exotic berry vineyards crop up everywhere in Vermont. I enjoy beer myself, but you haven't lived until you've tried elderberry, or lingonberry wine. I'm hoping mead comes back in style.https://t.co/xFKLeJ4Nmn

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7/17/2020
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UltimApe@ultimape• about 5 years ago
Replying to @ultimape

Going to make ambrosia some day.https://t.co/e6AYerAbrH

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UltimApe@ultimape• over 5 years ago

@garyvee Do you have a book on wine? I wanna learn about alcohol's impact on FAAH genes and see if I can recreate the terpene profile of the plants they would have put in absinthe.

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7/17/2020
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UltimApe@ultimape• about 5 years ago
Replying to @ultimape

A wine that heals the heart, and the soul.https://t.co/RWGq0wNJtl

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UltimApe@ultimape• over 5 years ago

Some may call it baking chocolate...But me? I call it bacteria poop!No one can stop me from eating it, now that I live on my own.The Ambrosia.https://t.co/E1H9SuhkvKhttps://t.co/TdteNIxjLo

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7/17/2020
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UltimApe@ultimape• about 5 years ago
Replying to @ultimape

The mythical bacterial organ in the rectum that controls your emotions, synonyms with soul.https://t.co/IyCGVXrglx

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UltimApe@ultimape• over 5 years ago

"interventions designed to diminish oxidative damage and support methylation capacity could improve the health of individuals afflicted with ASD"https://t.co/PSPPb8vt7T

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7/17/2020
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UltimApe@ultimape• about 5 years ago
Replying to @ultimape

All ancient healing rituals must necessarily have some form of "shirikodama" in their lore.https://t.co/pHAUmZ8Wds

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UltimApe@ultimape• over 5 years ago

"such as [immunity], [anit-pathogens], host nutrition including production of [SCFAs] important in host energy metabolism, synthesis of vitamins and fat storage [...] making it an essential organ of the body without which we would not function correctly" https://t.co/IfRDxMICp5

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7/17/2020
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UltimApe@ultimape• about 5 years ago
Replying to @ultimape

Stumbling around like a drunkard's walk.https://t.co/ipk7DLEAKt

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UltimApe@ultimape• about 5 years ago

@WoodIsGood6 @Austen You are stumbling upon the journal of a mad scientist detailing his ascent to biohacked godhood, through the power of ants, hibernation, and wine. I'm not settling until I'm immortal. https://t.co/mQJzK47xiL

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7/17/2020
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UltimApe@ultimape• about 5 years ago
Replying to @ultimape

Holy shit. You can ferment hot sauce.https://t.co/mvVRtoLK2nThis makes me feel things.https://t.co/L7zTZGH2kZ

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UltimApe@ultimape• about 5 years ago

This is a syringe full of cayenne pepper extract.And a pill filling tray (not shown: enteric coated capsules)Just in case you thought I was joking.https://t.co/Rqlgm0GVOb https://t.co/Z0upDtysyF

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7/17/2020
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UltimApe@ultimape• about 5 years ago
Replying to @ultimape

Just reading about Galen's writings on midwifery in a book about the history of massage. https://t.co/RF8Q0cxIoe

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8/11/2020
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UltimApe@ultimape• about 5 years ago
Replying to @ultimape

Why were the ancients obsessed with blood?https://t.co/vyHlSxtiFf

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UltimApe@ultimape• about 5 years ago

@Evolving_Moloch It's amazing how many herbal remedies thru history, associated with midwifery, hit the smooth muscle associated pathways. Anything that improves Nitric Oxide seems to also assist with crohn's associated intestinal blood flow and brain vessel expansion. https://t.co/j3SDNVXFJp

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8/11/2020
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UltimApe@ultimape• about 5 years ago
Replying to @ultimape

My body, it's under attack.Goes into lockdown.Blood pressure raise,extremity temperature drop,nutrient flow is halt,the farm that is the gut: left to rot.Calm your self. Calm the immune response.https://t.co/izx7Wmqt8D

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UltimApe@ultimape• over 5 years ago

"the pulsing flow of freeway and street traffic pumping packets of human energy encased in automobiles into cities and other urban clusters are virtually identical, when sped up, to the pulsing flow of blood coursing through the arteries"https://t.co/q2QZluu5Nh

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8/11/2020
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UltimApe@ultimape• over 4 years ago
Replying to @ultimape

Earlier in this thread, I referred to sulfites as the thing preventing alcohol production. I may be confusing it with nitrite related process https://t.co/DU12bKAcuv and other fermentation stoppers. https://t.co/xT8dEJI6sghttps://t.co/Qw8fy7sqBy

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UltimApe@ultimape• over 4 years ago

Oh noes, your wine might smell funny. Better put stuff in it that destroys yeasts.https://t.co/YZ2fJMFuFO"Sulfites inhibit the growth of four species of beneficial gut bacteria at concentrations regarded as safe for food"https://t.co/pQaJAESSnxOhhttps://t.co/xwjdVCZCqz

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1/13/2021
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UltimApe@ultimape• over 4 years ago
Replying to @ultimape

It seems the sulfites are added to prevent the wine from turning to a vinegar. which is technically also a form of fermentation, and the natural result of bacteria entering the wine that can consume the alcohol. This bacterial process seems to need lower alcohol %.

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1/13/2021
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UltimApe@ultimape• over 4 years ago
Replying to @ultimape

So while my mental model of sulfites being bad for bacteria still hold... the process in wine is more detailed. I learned this by trying to intentionally make vinegar from one.https://t.co/V1vxcOrlAh

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UltimApe@ultimape• over 4 years ago

@Mithreu @Grimhood I just stumbled on a curiosity about wine. Apparently histamines, tannins, and sulfites prevent wine from turning into a vinegar (a bacterial process). There are a bunch of products meant to reduce them.Have you tried / had luck with anything like that?

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1/13/2021
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UltimApe@ultimape• over 4 years ago
Replying to @ultimape

If you let wine fully ferment with S. cerevisiae, it is harder for those bacteria to set up shop because the alcohol % is too high. You have to dilute the wine a bit to encourage vinegar production. https://t.co/pNVM2e2lOT

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1/13/2021
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UltimApe@ultimape• over 4 years ago
Replying to @ultimape

So it's not 'correct' to frame this as the FDA 'force them to stop the fermentation with sulfites'. Adding sulfites is a result of early stopping of fermentation to prevent high alcohol %.https://t.co/xwjdVCZCqz

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UltimApe@ultimape• about 5 years ago

Thinking a lot about how FDA regulations require alcohols to be neutered with sulfur dioxide to meet alcohol % guidelines, and how that might be killing lactic acid bacteria in our gut.https://t.co/1ERS3dgPDt

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1/13/2021
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UltimApe@ultimape• over 4 years ago
Replying to @ultimape

The obvious answer here is to let the fermentation process do its thing, and create a culture where people water down their wine to low % alcohol on demand, allowing the high % to naturally prevent vinegarization.But I digress. https://t.co/Y0z0vbakMS

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1/14/2021
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UltimApe@ultimape• over 4 years ago
Replying to @ultimape

This exploration is because I wanna figure out what it is that prevents our microbiome from producing as much hydrogen peroxide as I suspect was historically common. It seems Saccharomyces cerevisiae is particularly resistant to hydrogen peroxide. https://t.co/csAVogV5h9

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1/14/2021
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UltimApe@ultimape• over 4 years ago
Replying to @ultimape

Seems reasonable to expect wine producing S cerevisiae may need that for some reason. It makes me wonder why it would have that adaptation. So I've been looking at the process of vinegar bacteria taking hold as a sort of competitor.https://t.co/4xD6KHwUc5https://t.co/RmHtZFmk7a

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UltimApe@ultimape• over 5 years ago

Thinking a lot about bacteria that produce hydrogen peroxide as part of ecosystemmic coopetition with e-coli strains in our gut.https://t.co/CXqU768yLq https://t.co/QvWIjPZLsm

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1/14/2021
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UltimApe@ultimape• over 4 years ago
Replying to @ultimape

I also think it would be cool if I could engineer a gut microbiome that sours wine for me. This would makes it so I can drink more red wine before I get inebriated. https://t.co/4rk2r8YVcD

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UltimApe@ultimape• over 5 years ago

Wondering about training my gut bacteria to make it so I can drink wine without getting innebreiated by acting as a substitute for substitute for alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH)https://t.co/XUZXFrei6w https://t.co/bTsihzWlDK

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1/14/2021
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UltimApe@ultimape• over 4 years ago
Replying to @ultimape

Please study hydrogen peroxide's localized production as an intercelluar antiseptic. The experts I talk to about it have no Idea what I'm talking about. I've literally told a rocket scientist he was wrong about H2O2.https://t.co/4VmieFIbnK

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UltimApe@ultimape• over 5 years ago

I argued with a literal rocket engineer (with patents) on the potential explosion and fire risk of heating H2O2 to act as an antiseptic; This was less than a week ago.What if the experts are wrong?https://t.co/4bHlYe2JDN

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1/14/2021
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UltimApe@ultimape• over 4 years ago
Replying to @ultimape

> They had lower counts of Bifidobacterium adolescentis, Faecalibacterium prausnitzii, and Eubacterium rectale. These species, as the authors explain, have “immunomodulatory potential.”https://t.co/xMIWj4YjW7

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1/14/2021
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UltimApe@ultimape• over 4 years ago
Replying to @ultimape

> "after realizing that wealthy countries with a good medical infrastructure [...] were among the hardest hit by the virus. The “western diet” that’s common in these countries is low in fiber"https://t.co/SxEEAXrI1ehttps://t.co/Qc3VBABSKj

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UltimApe@ultimape• about 6 years ago

Eaing 'umble pie... or more literally selecting food with high levels of connective tissue to ensure my stomach ferments animal fibers into butyrate and other anti-inflammatory products. https://t.co/uWdp6rBaG7

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1/14/2021
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UltimApe@ultimape• over 4 years ago
Replying to @ultimape

"Intrinsic and inducible resistance to hydrogen peroxide in Bifidobacterium species"https://t.co/4PgeQjc5OU

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1/14/2021
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UltimApe@ultimape• over 4 years ago
Replying to @ultimape

"co-cultivation [...] Bacteroides adolescensis was able to promote the growth of F. prausnitzii. [...] Bifidobacteria [main producers of acetate] in the colon and [studies report] low levels of Bifidobacteria have been associated with several diseases "https://t.co/w9EAAefq44

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1/14/2021
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UltimApe@ultimape• over 4 years ago
Replying to @ultimape

"Butyrate is generated by [Firmicutes microbes] (including [F. prausnitzii], Roseburia spp., [E. rectale], Eubacterium hallii and Anaerostipes spp.) via the butyryl-CoA:acetate CoA-transferase enzyme or phosphotransbutyrylase and butyrate kinase pathway"https://t.co/qL3hzqCwgZ

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1/14/2021
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UltimApe@ultimape• over 4 years ago
Replying to @ultimape

Fix your gut.https://t.co/sqerha2XOi

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UltimApe@ultimape• over 4 years ago

Collagen, Butyrate, Inflammation, Mucosa, Hydrogen Peroxide, THC, Anandamide, Endocannabinoid.https://t.co/KGjPmd8pGP

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1/14/2021
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UltimApe@ultimape• over 4 years ago
Replying to @ultimape

Fix your gut, fix your gut, fix your mother f*cking gut.as a song https://t.co/vSkLWkBobt (nsfw)https://t.co/wAjl8yRY4y

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UltimApe@ultimape• almost 5 years ago

@mchapiro "secret hydrogen peroxide as a virucidal component and also secret anti-viral substances disturbing virus transmission. Furthermore, hydrogen peroxide can combine with several mammalian peroxidases, [...] in order to make a potent virucidal combination"https://t.co/3E3NL7j4wF

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1/14/2021
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UltimApe@ultimape• over 4 years ago
Replying to @ultimape

Please, you must understand.https://t.co/ps0xFdaufx

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UltimApe@ultimape• almost 5 years ago

@mchapiro This came out yesterday. Gut bacteria literally interact with mucosa via hydrogen peroxide https://t.co/jtnG6xcEgYand a tie to covid and mucosa: https://t.co/30FfokQXpC that no one is paying any attention to.Your tech may be hitting factors could be activating a lot of this.

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2 0
1/14/2021
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UltimApe@ultimape• over 4 years ago
Replying to @ultimape

Driving my self insane.https://t.co/vepRHQIG2U

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UltimApe@ultimape• about 6 years ago

@TylerWLeBaron I fixed my genetic lactose intolerance thru inferences in suspicions on why the hydrogen breath test is used to detect it in people. By biasing my gut toward strains of hydrogen peroxide producing bacteria.Looking for cheap and easy ways to test this stuff to prove it.

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1/14/2021
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UltimApe@ultimape• over 4 years ago
Replying to @ultimape

Ants. ANTS LITTERALLY EAT HYDROGEN PEROXIDE PRODUCING SUBSTANCES TO FIGHT DISEASE.It's self medication.https://t.co/PDxjBy49SV

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UltimApe@ultimape• about 10 years ago

@leifr7 is this the same publication? http://t.co/oQmisuiNcY re: ants eating hydrogen peroxide? @bslindgren @CharissaB @ZombieAntGuy

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1/14/2021
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UltimApe@ultimape• over 4 years ago
Replying to @ultimape

HYDROGEN PEROXIDE BURNS YOU. DO NOT DRINK HYDROGEN PEROXIDE.FIX YOUR GUT, THEY PRODUCE IT LOCALLY ON DEMAND.

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1/14/2021
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UltimApe@ultimape• over 4 years ago
Replying to @ultimape

9 months 19 days 8 hours 31 minutes 55 secondshttps://t.co/SvA4lmPgBf

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UltimApe@ultimape• over 5 years ago

I'm trying to figure out how to engineer my skin to feed a colony of microbes that produce erythromycin and other anti-viral compounds to act as a barrier against disease.Don't need to wash your hands if your body's holobiont is naturally antiviral. 😇🤫https://t.co/1rvJi1yNwG

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1/14/2021
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UltimApe@ultimape• over 4 years ago
Replying to @ultimape

I wanted to become a plague doctor.https://t.co/NtvS0drJZa

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UltimApe@ultimape• over 5 years ago

I volunteer as tribute. https://t.co/tJrUybFPiq

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0 0
1/14/2021
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UltimApe@ultimape• over 4 years ago
Replying to @ultimape

I am not fucking around.https://t.co/VPUgpoWSfp

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UltimApe@ultimape• over 4 years ago

I am learning about fabric chemistry so I can knit my own flame proof lab coat. Going to dye it with antimicrobial wines so it looks blood red. Going to smell fantastic.https://t.co/YWkrt6xm5w

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0 0
1/14/2021
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UltimApe@ultimape• over 4 years ago
Replying to @ultimape

I don't know how to communicate. I'm literally autistic because of this:https://t.co/Jgvm4Fj7SL

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UltimApe@ultimape• almost 8 years ago

A family line predisposed to immune system problems -> risk of children with autism. https://t.co/b19BOmI7BQ [2017]

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1/14/2021
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UltimApe@ultimape• over 4 years ago
Replying to @ultimape

My entire family is immune system problems.Fixing this has been my obsession.https://t.co/AfnlRyO6YA

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UltimApe@ultimape• over 5 years ago

Every single member of my family is immune compromised in some way.I'm not really panicking. I'm just in a state of rapid innovation.https://t.co/gPcbMZdKTa

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1/14/2021
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UltimApe@ultimape• over 4 years ago
Replying to @ultimape

I can't stop crying.https://t.co/7Oha6ahxQN

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UltimApe@ultimape• over 5 years ago

Ya'll getting M.S. symptoms and you don't even fucking know it.

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1/14/2021
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UltimApe@ultimape• over 4 years ago
Replying to @ultimape

"Compared with patients on standard care, our pilot clinical study showed that more COVID patients who received our microbiome immunity formula achieved complete symptom resolution"https://t.co/G7oWVgeo8D

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1/15/2021
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UltimApe@ultimape• over 4 years ago
Replying to @ultimape

Bruh, do you even [encourage your mucus to harbor bacteria to act as the first line of defense in your immune system]https://t.co/Z2PD0FJ2yw

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UltimApe@ultimape• over 5 years ago

So while everyone else is dosing up on Malaria drugs and synthetic antibiotics, I'll be drinking Kombucha, and eating zinc heavy foods. https://t.co/wpUPoGh1MQ and helping my gut bacteria produce erythromycin naturally instead of just killing everything off and getting psychosis.

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0 0
1/15/2021
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UltimApe@ultimape• over 4 years ago
Replying to @ultimape

[insert tweet, repeat]https://t.co/x0oYWN6GwC

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UltimApe@ultimape• over 6 years ago

insert tweet about how modeling the immune system as a colony of ants makes everything fall into place.https://t.co/BJrZd54VD8

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1 0
1/15/2021
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UltimApe@ultimape• over 4 years ago
Replying to @ultimape

"A demon of plague, the Asag was known to dwell in the human body and cover the person like clothing. The monster was especially known for causing head fevers. In the end, the Asag would end up paralyzing the person he had infected" https://t.co/Jt7v9SqNgk https://t.co/a9FNOoYsTH

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UltimApe@ultimape• over 4 years ago

I dream of demons. I know their names.https://t.co/a94Gx6KrDN

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1/31/2021
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UltimApe@ultimape• over 4 years ago
Replying to @ultimape

"Guillain–Barré syndrome is a neurological disorder where the immune system responds to an infection and ends up mistakenly attacking nerve cells, resulting in muscle weakness and eventually paralysis."https://t.co/4YUH5C8AaV

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1/31/2021
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UltimApe@ultimape• over 4 years ago
Replying to @ultimape

"suggests that skin manifestations, when taken into account with other situational factors (such as profession and patient history) should be taken into proper consideration by frontline physicians as possibly being caused by SARS-CoV-2"https://t.co/kW5f86YOMa

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1/31/2021
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UltimApe@ultimape• over 4 years ago
Replying to @ultimape

I know the name of the demon."Molecular clock dating analyses of coronaviruses suggest that the most recent common ancestor of these viruses existed around 10,000 years ago."https://t.co/E9TVna0Zln

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1/31/2021
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UltimApe@ultimape• over 4 years ago
Replying to @ultimape

"Bacteroidetes make up about 40 to 50 percent of the 200-plus microbial species in the gut of most of us [...] Perhaps in dysbiotic people with lower numbers of these [....] less resistance when encountering a virus and therefore more severe infection." https://t.co/blNRNWmbdk 🤪

1 0
4/14/2021
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UltimApe@ultimape• over 4 years ago
Replying to @ultimape

"How many [...] studies of Th-17-mediated autoimmune diseases, performed prior to Ivanov and Littman’s identification of [segmented filamentous bacteria]’s role in immune system development, could be explained by the presence or absence of SFB?"https://t.co/ph4PiO8vHL

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4/14/2021
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UltimApe@ultimape• over 4 years ago
Replying to @ultimape

"These data demonstrate that gut microbiota can undergo profound changes in commercial laboratory mice within specific vendor barrier rooms that have the potential to alter experimental reproducibility"https://t.co/FKphDphPuShttps://t.co/OW9CMPhez1 https://t.co/bTezsFU0oE

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UltimApe@ultimape• almost 5 years ago

So many mice fall out."Serotonin Transporter Deficiency is Associated with Dysbiosis and Changes in Metabolic Function of the Mouse Intestinal Microbiome"https://t.co/nW08w4FF3W

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0 0
4/14/2021
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UltimApe@ultimape• over 4 years ago
Replying to @ultimape

I view mushrooms and trees as elaborate biological machines that produce clouds so that microbes can colonize the earth... https://t.co/dqlMN7O82N

2 0
6/8/2021
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UltimApe@ultimape• over 4 years ago
Replying to @ultimape

And trees actually make clouds too, its really weird.https://t.co/hVtSUJKHiY

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6/8/2021
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UltimApe@ultimape• over 4 years ago
Replying to @ultimape

Tree aerosols.https://t.co/iSzkzoQ7fE

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UltimApe@ultimape• over 4 years ago

Also just strait up bacteria floating up there https://t.co/6iUJ0LyrKuDo you think trees sneeze collectively?https://t.co/O53GpZGg6w

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0 0
6/8/2021
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UltimApe@ultimape• over 4 years ago
Replying to @ultimape

Let's burn trees down. Then maybe they'll stop sneezing on us.https://t.co/cWrrtDstxL

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6/8/2021
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UltimApe@ultimape• over 3 years ago
Replying to @ultimape

I wanna live in a place where they let me grow plants.https://t.co/4l4orCdlBR

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UltimApe@ultimape• almost 4 years ago

The other story:"The problem is that most of these plants that we’ve discovered don’t grow in huge clumps; you’ve got to search for them for days to find one sample. So I have a complex of greenhouses, which I built, where we try and incubate them."https://t.co/ziqMITgOpF

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3/14/2022
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UltimApe@ultimape• over 3 years ago
Replying to @ultimape

I have all this backyard, but the person who owns the house is uncooperative with any of my ideas.https://t.co/6qIho2YPqi

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UltimApe@ultimape• about 5 years ago

Grow plants that can suck up glyphosate from the soil, then feed them to oyster mushrooms.Generate a food source rich in Taurine and clean your soil of pesticides. There is hope.https://t.co/pODrlWWzaa

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2 0
3/14/2022
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UltimApe@ultimape• over 3 years ago
Replying to @ultimape

Back at the apartment I started collecting things to do it too. I still have all the food safe containers and makeshift DIY seeding stuff.https://t.co/84pv7n7oo4

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UltimApe@ultimape• over 4 years ago

I'm going to grow some plants soon.https://t.co/smrKLGXTs6

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0 0
3/14/2022
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UltimApe@ultimape• over 3 years ago
Replying to @ultimape

There are so many weird plants I think would be useful to grow.https://t.co/Xunfl32Yb0

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UltimApe@ultimape• over 5 years ago

I'm going to be buying a bunch of indoor gardening equipment with my next paycheck. I wanna grow plants that induce abortions.Stuff that smells good and has funny taste'ing roots.Molesting plants to make them long and hardy.https://t.co/PzS5m649NQ https://t.co/5U4DQkrFSj

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1 0
3/14/2022
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UltimApe@ultimape• over 3 years ago
Replying to @ultimape

I want to grow things that heal.https://t.co/WVj6t7fzZH

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UltimApe@ultimape• over 3 years ago

If aspects of these herbs help with DNA damage associate with ionizing radiation, its conceivable they might be useful to treat glioblastoma?https://t.co/uO2Nt7ZQFO

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1 0
3/14/2022
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UltimApe@ultimape• about 3 years ago
Replying to @ultimape

Wait until you start ranting about human hibernation and on how we've known about the impacts of the endocannabinoid's system for like 4000 years.https://t.co/u9gy15nmql

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8/4/2022
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UltimApe@ultimape• about 3 years ago
Replying to @ultimape

Soon.jpghttps://t.co/KsI9i6jTc3

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8/4/2022
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UltimApe@ultimape• about 2 years ago
Replying to @ultimape

Tired: learning how gut bacteria can prevent hookworm and roundworm infection to fight diseases.https://t.co/n89SZ1t2zU

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8/14/2023
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UltimApe@ultimape• about 2 years ago
Replying to @ultimape

Inspired: learning how to eat random dog shit safely so when your neighbor doesn't pick up after their dog you can run over and thank them for their gift...https://t.co/qLPYqEgI2f

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UltimApe@ultimape• about 6 years ago

"The vast majority of dogs won’t eat feces that are more than two days old, suggesting that they prefer the fresh stuff for its microbial punch, she says, especially when they’re attempting to regenerate their own gut flora."https://t.co/MQ4AgRlIr8

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1 0
8/14/2023
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UltimApe@ultimape• about 2 years ago
Replying to @ultimape

Hired: figuring out that most mice studies on Giardia are suspect because disease resistance is transferable via gut bacteria and no one bothers to account for this.https://t.co/c0GBO3AznZhttps://t.co/62rr0bfche

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UltimApe@ultimape• about 6 years ago

"You will read in several places online that dogs can get a parasite called giardia from eating goose poop. This is not true. The type of giardia that affects geese is very host-specific which means that even if a dog ingested it, they would not get sick."https://t.co/T7wyWAW0hl

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1 0
8/14/2023
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james, the giant peach@JimmyRis• over 5 years ago
Replying to @ultimape

@ultimape Why abortions?

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5/18/2020
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UltimApe@ultimape• over 5 years ago
Replying to @JimmyRis

@JimmyRis because there are weird parallels betwen herbal plants that improve autism/schziophrenia that seem to also help with inducing pregnancy. I think its because abortions are immune system driven phenomena - pre term pregnancy due to sickness is common in animal kingdom.

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5/18/2020
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UltimApe@ultimape• over 5 years ago
Replying to @ultimape

@JimmyRis Both estrogens and testosterones have been shown to immunologically active.

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5/18/2020
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james, the giant peach@JimmyRis• over 5 years ago
Replying to @ultimape

@ultimape Hmm what sorts of improvements are seen re:autism?

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5/18/2020
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UltimApe@ultimape• over 5 years ago
Replying to @JimmyRis

@JimmyRis L reuteri's impact on autism seems to be partially thru it's impact on testosterone.

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5/18/2020
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james, the giant peach@JimmyRis• over 5 years ago
Replying to @ultimape

@ultimape And the impact?

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5/18/2020
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UltimApe@ultimape• over 5 years ago
Replying to @JimmyRis

@JimmyRis For me, when I augmented with black cohosh, my balls grew bigger and I basically stopped having sensory problems. That seemed to be affected by the weather / sun light, so I think there's something happening with TRP pathways.

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5/18/2020
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UltimApe@ultimape• over 5 years ago
Replying to @ultimape

@JimmyRis L reuteri seems to increase otytocin indirectly. So it improved my sociability. It also made my skin glow and hair healthy like a pregnant woman's will sometimes do.https://t.co/8TzZOqpob4

3 0
5/18/2020
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UltimApe@ultimape• over 5 years ago
Replying to @ultimape

@JimmyRis I'm doing a lot of other stuff to improve my metabolic profile, but the L reuteri is one of the biggest drivers. I think the testosterone boost is mitigating my immune system being too aggressive.

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5/18/2020
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UltimApe@ultimape• over 5 years ago
Replying to @ultimape

@JimmyRis One I got a handle on my crohn's symptoms (partly an overactive immune system issue) I basically stopped having autistic meltdowns except in worst situations. If I don't get kefir w/ L reuteri in it for a couple months, a lot of my improvements start to slip a bit & less stable.

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5/18/2020
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james, the giant peach@JimmyRis• over 5 years ago
Replying to @ultimape

@ultimape Pretty compelling, really glad you found this for yourself I've been looking at reuteri and at natto (fermented soybeans) for microbiome modulation ever since I was turned onto them by a body hacking guru

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5/18/2020
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james, the giant peach@JimmyRis• over 5 years ago
Replying to @JimmyRis

@ultimape Got the lowdown at the same gathering mentioned here https://t.co/FztKGsTntn

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james, the giant peach@JimmyRis• over 5 years ago

@Grimhood A bit yeah: I wore a head harness with 8 individual IR nodes + 1 you clip on your nose to shoot straight up your nostril Was at the house of some folks who are verryyy into it, neurohacker types in California

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0 0
5/18/2020
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UltimApe@ultimape• over 5 years ago
Replying to @JimmyRis

@JimmyRis What frequency of IR? There's some anti-aging stuff having to do with high intensity sunlamps that looked promising given how sun seems to affect testicle size.

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5/18/2020
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james, the giant peach@JimmyRis• over 5 years ago
Replying to @ultimape

@ultimape I would peep this talk, I don't recall the frequency I'd need to rewatch https://t.co/PQkfAkaJAH

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5/18/2020
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james, the giant peach@JimmyRis• over 5 years ago
Replying to @JimmyRis

@ultimape Same concept behind 'sungazing'

1 0
5/18/2020
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james, the giant peach@JimmyRis• over 5 years ago
Replying to @JimmyRis

@ultimape intracranial IR stimulation of glial cells and pineal gland

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5/18/2020
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james, the giant peach@JimmyRis• over 5 years ago
Replying to @JimmyRis

@ultimape I'm getting the DIY recipe for a headset setup from the guy who turned me onto it, will share

1 0
5/18/2020
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UltimApe@ultimape• over 5 years ago
Replying to @JimmyRis

@JimmyRis I suspect that a lot of that is an indirect effect of the immune system shifting and they aren't directly stimulating it. I am looking at this space via the 'immune-pineal axis'.https://t.co/PKpXXz4r75

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UltimApe@ultimape• over 5 years ago

"This coordinated shift of the source of melatonin driven by NF-ÎşB is called the immune-pineal axis. Finally, we discuss how this concept might be relevant to a better understanding of pathological conditions with impaired melatonin rhythms "https://t.co/tsx44okWEH

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5/18/2020
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goblin waifu@goblinodds• over 4 years ago
Replying to @JimmyRis

@JimmyRis @ultimape if you can find it, the frozen natto with flavor packets is actually really tasty (i like dashi+mustard)

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6/6/2021
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james, the giant peach@JimmyRis• over 4 years ago
Replying to @goblinodds

@goblinodds @ultimape Wonder how much the freezing mucks with the biotics 🤔

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6/6/2021