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What the fuck.What are the chances that the kind of sounds I'm extremely bothered by during meltdown states are also the same frequency spectrum of a female mosquitoes wing beats?https://t.co/iQCTqYdmz4That sound makes me want to leave. Instant panic. Heh,

How do I found out what the frequency domain of skrillex songs are?https://t.co/s5glky3ykxAnd also, how can I measure hair standing on end? https://t.co/MAkB17Z9bl

Something about mosquitoe's limbic system acting as a cock-block."The funnier the content, the more blood flow to the NAcc was measured, confirming its role in humor appreciation."https://t.co/nhdR7JualVhttps://t.co/xSUlMRlQYU

Curiosity."cure ios city"https://t.co/GYcCJhwFhC

"laughter increases your blood flow by dilating the inner lining of blood vessels, which is called the endothelium.Laughter causes the release of beta-endorphins in the hypothalamus, which leads to the release of nitric oxide, which dilates the vessels."https://t.co/9ZRcZeyJkx

"Listening to joyful music may be an adjunctive life-style intervention for the promotion of vascular health."https://t.co/PU3PpFi8xGhttps://t.co/vJYp0dvZZG

DMT"Regular dance movement therapy increases NO bioavailability in elderly women and it can slow down the age-related losses in endothelial function consequent to prevention of cardiovascular diseases."https://t.co/fu9GEE0TClhttps://t.co/DIGALxCAkQ

"social dance supported efforts to relieve physical and psychological degradation, provided a strong sense of pleasure and continuity as well as a vehicle for the changes required by aging"https://t.co/Z0tKAH2DpP

Worshiping ancient sun gods who give us life, with a ritual of song and dance. A celebration."These findings provide neurochemical evidence that intense emotional responses to music involve ancient reward circuitry in the brain"https://t.co/sLSzUNHpuZhttps://t.co/a18qUHbL3t

"a pelvic exercise program, in the form of recreational dancing, that females could follow more easily and participate in for longer by engaging their interest. "https://t.co/RaV78PXM1nWhy does this stuff end up sexualized?https://t.co/4sLr6lITj2https://t.co/9yhHCYAVHn

I'm... not joking about proxy learning about diabetes thru erections."Suppression by Prolactin of the Electrically Induced Erectile Response through its Direct Effect on the Corpus Cavernosum Penis in the Dog"https://t.co/AvIhruZPLk"Smooth muscle"!https://t.co/sFNtD7aQbH

"methodological problems and definitional discrepancies in some publications, results have to be interpreted cautiously. Research in ASD and incontinence is scarce. More systematic research including state-of-the-art assessments is needed."https://t.co/v0QbRN77ls¯\_(ツ)_/¯

I'm trying to find out if music makes people pee."Each arrector pili is composed of a bundle of smooth muscle fibres which attach to several follicles (a follicular unit), and is innervated by the sympathetic branch of the autonomic nervous system." https://t.co/VDstRIfSqc

"Any condition that affects the nerves or muscles of the urinary or bowel system, including injuries or surgeries to the pelvic area or spinal cord, neurological diseases, multiple sclerosis, infections or diabetes, can cause incontinence. "https://t.co/hxq6JArnFJ

Is the MS link to urinary incontinence a mashup of immune related muscle decay combining with smooth muscle weirdness?Does it hurt? Only when I laugh with my belly.https://t.co/nj74Glp0M4 https://t.co/NOf3QsDe90


Whoa. Not only is there a connection between pelvic floor function and bladder control, the ties between dance and immune function seem to be strong enough that there is an M.S. Community around Belly dancing. Amazing. https://t.co/PrxrRLOFxQ


Ball room dancing improved this guy's M.S.https://t.co/IqM36L9J5FYet another thing that I should copy after Tim Ferris. Strange how often that shows up in my research.

Turns out urination frequency, concentration, and volume are actually medically relevant.https://t.co/6SS7VwhpTwSo I may be able to find out if dancing makes me pee.Awkwardhttps://t.co/8cwqAQ5EMb https://t.co/yuWjuIKOTS


I can't stop thinking about people bathing in piss on a gif that I saw on 4chan.https://t.co/EQBGSEvbhvhttps://t.co/xouGUjOlJP

heh"Glutamate is an excitatory neurotransmitter in pathways that control the lower urinary tract. Serotonergic pathways facilitate urine storage. Dopaminergic pathways may have both inhibitory and excitatory effects on urination."https://t.co/fLAaF3skqPhttps://t.co/dTDM4ewMGg

Fascinated by the idea of an alchemist and barrels full of piss.Do you know if this has been peer reviewed?https://t.co/wzfarHgI8Qhttps://t.co/loEzg8Boo9

"developed cow urine based disinfectant. They used neem,ritha, pine oil extracts in cow urine."https://t.co/IG29uos060No. I don't want to be right.https://t.co/laoRaj5HE4

I need to find how long ago the use of urine in medicine became taboo'd.https://t.co/AHLYyAs2Lr

"obsessed with secrecy, deliberately described their experiments in metaphorical terms laden with obscure references to mythology and history. For instance, text that describes a “cold dragon” who “creeps in and out of the caves” was code for saltpeter" 😈https://t.co/z7H12wegnJ

"There's a sign on the wall, but she wants to be sure'Cause you know sometimes words have two meaningsIn a tree by the brook, there's a songbird who singsSometimes all of our thoughts are misgiven"https://t.co/GwOUNAmTGqhttps://t.co/hdqw4jgW0T

We shall rue the day.https://t.co/2zGSQ2u9cI

Rue is used to stop a heart from beating fast https://t.co/0gG9IkycnqThis is clearly a creative way to hint that you wanna bang the girl so hard you get a pounding heart and will need medicine for it.In context where medical herbs were common knowledge, this is really kinky. https://t.co/doXdKb1sWB

Ah, I see you have discovered your glassware is cracking. Have you heard about the magic of the witch's broom?https://t.co/ux6HI1wqxR

"Смотришь нежно, ждешь его внимания.Чувства те же, но не понимаю -Сколько можно жить, любя, украдкой?" 🎶https://t.co/hfJXU9OC56https://t.co/UjY8aA75hT



Have you considered that ancient witch craft and alchemical practice evolved metaphoric language to be able to hide from the tyrannical nature of the church?What do you do if science is outlawed? Learn to pun.https://t.co/k9clQ8cfry

"folk names for the plants they regularly used, like eye of newt for mustard seed or wool of bat for moss. Many historians believe that witches used these gruesome sounding names so that their spells and herbal remedies could not be easily copied."https://t.co/z5CZboRn1l

Why did Leonardo Da Vinci's Notebooks have mirror writing? Was there more too it than simply brain wiring? https://t.co/p6YxOxliZZOf course! He was trying to avoid being scooped.https://t.co/se9kFPqo1J

Secret fraternities hiding behind hazing rituals as a costly signal of being worthy of knowing forbidden knowledge?https://t.co/YDRwJjBajY

Wringing dew drops of signal from the dirty fabric of society we call noise.Don't let a good story get in the way of the truth.https://t.co/ut9PllsVnK

Distilling wisdom from the sweat rags of society.https://t.co/W7ec7QQIF3

Ideas perhaps linger on, existing as tradition, embedded in ritual & metis. Ideas captured by other traditions an cultures, locked out by language barriers. If we're lucky they can be distilled.This is "Intellectual Dark Matter" as coined by @SamoBurja https://t.co/OU9EW04j40

"If they are so great, why aren’t they just taught in the introductory class? Partly because even the best people in the field can’t quite say what the principles are, because tacit understanding does not always enable explicit explanation."https://t.co/qBlM8zABQL

Imitate vs replicate.https://t.co/qM1ps70fkd

I took this literally.Now I'm learning about how to make an (al)embic⚗️using clay and glass glazing, feeding it thru a series of cooling pots to distill raw terpenoids from plants, and reverse engineering microbiology from ancient witchcraft rituals.https://t.co/47v0SLkMjv

"What separated Feynman from his peers wasn't necessarily raw intelligence. It was the way he saw the problem. He had a broader set of mental models."https://t.co/hcaak2Is2w

"There was no importance to what I was doing, but ultimately there was. The diagrams and the whole business that I got the Nobel Prize for came from that piddling around with the wobbling plate."https://t.co/kxqcJlkvbT

PlayRePlayCreateReCreateRe:creativityReCreativityhttps://t.co/D0vF9dDqIa

Someone commented on this thread, and I made a connection in my head. TRPV4 is involved in bladder related smooth muscle control?https://t.co/BrMAjh1VqW https://t.co/KGCmWAML8j


Was thinking about how the intestine has an oscillatory motion where the TRPV1 & TRPV4 controlled smooth muscles cross talk to create a feedback signal.But balloons in our body don't.https://t.co/YuBpJW9OE3

I've made one of these before, In 5th grade(?)."The main feature of the `Morris dance` is the fool`s belabouring the heads of onlookers with what is traditionally an inflated pig`s bladder tied to a stick"https://t.co/oXE8PL6uwh https://t.co/v1OFXPOeMG


Gonna need to get me some pixie dust. https://t.co/x5SQTch9aH

It turns out that "magic pixie dust regrew my finger" wasn't fake. They were purifying stem cells from muscle tissue in pig bladders, and a brother of the founder spoke of his success before they completed the whole medical trial, and the news hyped it.https://t.co/o4LDvsu6NZ

If blood vessels dilating from laughter triggers TRPM8 activity, which in turn modulates TRPV4's action on letting nutrients out of capillaries and in to the muscles.*stretches*https://t.co/oQIbVSfQTv https://t.co/HRn9NdudSB


TRPM8 isn't just cold. also Stretch."stretching in MCs activates TRPV1, TRPV2, TRPV4, and TRPA1 channels, that it may be involved in synaptic transmission to sensory neurons, and that MCs could contribute to the mechanosensory transduction sequence"https://t.co/Uxjf4qUpgm

Bingo."further studies to elucidate NO pathways in neurodegenerative dementias could lead to a better understanding of their pathogenesis and improved therapeutic strategies, and therefore are certainly warranted." https://t.co/tw4bevyIVJhttps://t.co/S1MuFSZWPw

@Avantgardeish @nsreed I have a hunch that this is about brain blood flow and neuronal / blood vessel growth.There are some hypthesises about this in the literature, but I discover this on my own by exploring smooth blood vessel regulation as it relates to Raynaulds & Crohn's.https://t.co/iPqqbJbLkM

"those who got to laugh the 20 minutes away with the funny video scored better on short-term memory tests, researchers said. And salivary levels of the stress hormone cortisol -- a memory enemy of sorts -- were significantly decreased in the humor group."https://t.co/xdV7OyNGEG

Laugh with me.https://t.co/eCYwo8ONz5

Laugh with me."What this means is that humor actually engages the entire brain -- it is a whole brain experience with the gamma wave band frequency and humor, similar to meditation, holds it there; we call this being 'in the zone,'"https://t.co/pVV5iLMpMw https://t.co/qPRaT80N4x


Might make your dick work by aiding in vasculature repair, or at least stop cortisol induced insulin spikes from furthering stress induced exacerbations on diabetes and plausibly dementia (via improving blood flow in the brain).https://t.co/k2VqnUiYHK

Gonna go try to make my girlfriend laugh so hard she shits her pants (via TRPV1/TRPV4 activation via blood vessel dilation's impact on TRPM8).For health!https://t.co/RpwVgN0IJi

"Blood flow increased in nineteen of the twenty people after they watched "Kingpin." The increase was an average of twenty-two percent. Doctor Miller says that is similar to the effects of aerobic exercise."https://t.co/uxsoDb2L2ghttps://t.co/K3LZfLp9vV

Becoming the butt of a joke to cheer people up."Don't you know everyone wants to laugh?My dad said "Be an actor, my son, but be a comical one"They'll be standing in lines for those old honky-tonk monkeyshines"https://t.co/Oo62hOvjtyhttps://t.co/Y4ugHz8NpN

You know, it might not be the laughter that's getting people a little hot around the neck. There's a lot going on in this, uh, movie.https://t.co/qoLrliVq4X

*nervous tic activate*https://t.co/q1khIaomMA

So... That study on people watching "kingpin!" is supposed to be about laughter's role in blood flow. And the entire movie is about using sexual attraction to distract bowlers a scam.Wat.https://t.co/49fRe9TFRM

I wonder what the incentive structure is that a doctor at a medical institution would try to launder research about sexual arousal by telling lies about laughter.https://t.co/wfXRVOxqVQ

I keep finding studies appearing to be research on something really important to me, and then when I dig in further its basically someone watching an old popular movie, then taking medical readings.I can't get no respect (for rational study design).https://t.co/hKAtU4v4h4

The worst kind of science are those that tend to replicate, but unknowingly get their conclusions due to some akin to the Gettier problem within epistemology, and hide behind critical thinking + science hype.https://t.co/RsQJ70A5FA

I love finding science jokes. https://t.co/znRZt7iMGl


Current status: steelmanning urophagia and alkaline water.https://t.co/77KZg9CR9V

Oh fuck."TRPM8 polymorphisms associated with increased risk of IBS-C and IBS-M"https://t.co/FeESRrpQ6ghttps://t.co/oN0GppiuDD


Found a good article exploring the nature of bed wetting. It traces some of the problematic parenting beliefs (myths) that prevail in the west.https://t.co/R06nzEMmfwhttps://t.co/QTCc7O73Y1 https://t.co/MD0BmFYk12


It is upsetting to think that that western pop psychology driving shame (and abuse) over children wetting the bed is downstream of Freud having nightmares about his mother, pissing himself, and framing it as him wanting to fuck her ("wish fulfillment").

I kinda suspect Freud's "Magical" Cocaine habit might have something to do with his obsessions with viewing enuresis as being sexual. But I only have hunches. https://t.co/BpDjDehUWB

Imagining Freud taking Cocaine all the time and developing weird problems like Priapism or Erectile Dysfunction... Then psychologizing it all under some half-baked theories about getting horny around his mum and not understanding urolagnia kinks.https://t.co/uip4dOYUJB

I wonder if Freud ever gave Cocaine to his pupper.Or if use of cocaine impaired sense of smell."I’ve overcome that addiction, but it has cost me my sense of smell. Why did this happen, and what can I do?"https://t.co/UznrtIz9SLhttps://t.co/Q4puMRqL9K

"Freud loved the way cocaine made him feel. [...] For one, it did make him feel better when he was sad.He also was amazed at how it made him talk about things endlessly that he thought were locked away in his brain."https://t.co/5OQVRmuRji

I am not trying to glorify drug use. I'm trying to say Freud's thinking is not a good model for understanding psychological disease. Just so we're clear. https://t.co/aLhTbvweqF


Its weird to me how loss of smell is associated with aging (and age related disease) and with cocaine use.And how often people mistake age related sniffles with cocaine use. Similar shame driven myth dynamics as we see with wetting the bed IMHO.https://t.co/UNotqQyVlr

*sniffs*"These results suggest that [Substance Use Disorder] itself, apart from the contribution of comorbid medical conditions, may have increased the risk for COVID-19 infection, even among the vaccinated population."https://t.co/hlmuPrTdNz https://t.co/i9Q4ssXkm4


Does Cocaine makes you constipated? Vasoconstriction aught to lead to direct gut motility problems and exhibit the issues we seen in Crohn's Disease / IBS-C.https://t.co/D6RrU6S5L6https://t.co/mVvIyclAtO https://t.co/lDkssYq3zN


There is a line of reasoning that you can sample a patient's feces and after a period of time slowly adapt your own experiences by affecting how the gut microbiota in your own gut ecosystem adapt. I speculated Freud's ideas of anxiety and constipation were intrinsically linked.

What if Freud was literally full of shit?> It was a destructive influence, yes, but an influence nonetheless; through cocaine, Freud really may have “achieved something beautiful.”https://t.co/uVLvJyYpRl https://t.co/WXjpaUQG0F


I bet cocaine does really interesting things to intestinal mucus.https://t.co/FNQb85OpMC

"For example, whenever we attribute motive to another person, and use words such as "constricted," "repressed" and perhaps even the more accurate "anal retentive" to describe another person, we "speak Freud." The extent to which [...] will surprise"https://t.co/Ztxx3NRmNG

"in the 1970s and the 1980s, it was advertised as the safe and elite and cool drug to do. [...] All you had to do was read the old stuff in the 1880s. But no, it became a very popular recreational drug to be sure, well into the 1930s."https://t.co/P8Nwpetyps

I wonder when meaningful use of using FMT to treat disease would have stopped. I know Freud played a role here ala https://t.co/K2vRJyVUs5 but presumably he had been influenced by earlier memes?

"This is probably not because madness never produced excremental behaviours of this kind. The question then is why did this only result in a meaningful medical category of behaviour from the late nineteenth century onwards?" https://t.co/36aCsUEHrI https://t.co/5B8upkOvyN


The only thing I can think of is germ theory?1870shttps://t.co/JoRagRV4GB

Tired: Talk therapyWired: MedicationInspired: Meditation to calm your gut microbes, and eating bacteria waste as a prebiotic.Hired: Realizing all the norms around handling mental disease in western society occurred after the 1870s, co-occurring with the germ theory of disease. https://t.co/61begB6biP

hmmm.https://t.co/hidkEN4Fpchttps://t.co/TuCU0mNIjQ https://t.co/Msm6B4xKyz


Fuck. I've been here before.https://t.co/Jjb2Unz7ki

"Hey google, when was the flush toilet invented"Invented: 1596Widespread use: 1851haha.https://t.co/JrbT87VK7Vhttps://t.co/JdI0acymCh https://t.co/9GTvrlM3VU


@suchaone @__a__chimera__ I think this analysis is wrong for Americans/ when toilets were first adopted in the ~1850s, it was unlikely that shit floats given my understanding of dietary changes. Observation might be post-hoc. https://t.co/CYh8Ae5lSqTho it would be fun if designs shifted to reflect this.

She just showed me the book she's reading.Magical washrooms....It just disappeared into the void? 😳👉🕳️👈https://t.co/toTEt0Xgzd https://t.co/GqKfUOuKiT


Go home twitter. You are drunk.https://t.co/vSffSKYEMz https://t.co/wl90EYw4bC


I bet that Freud's "repressed memories" were actually a symptom of endemic pellagra and GI disorders driven by literal cocaine.Would be funny if the foundation of the western psychological tradition is just fucking wrong.Americanitis. LOL.https://t.co/5keLmtT7kt

I got some of those repressed memories right here.https://t.co/jzFyAsF7fz

I wanna recreate all the learned helplessness experiments but sample gut metabolome and microbiome. The variation in the dogs was really high IIRC. Rats + mice studies are already suspect because of completely ignoring water+food+environmental pathogens.https://t.co/9e7BEtSI2i https://t.co/6gBtyNxLiJ


What if everything you think you know about learned helplessness is wrong. What if the dogs microbes were killed from the stress, and the behavior we see is from lack of activation of dog's hippocampus to manage memory?Temporary catastrophic forgetting.https://t.co/PiFjKEtmME

Oooh this old article on Cocaine by @HamiltonMorris discusses possibility of learning effects via brain plasticity. I wonder of short term Cocaine use drives mTOR shifts thru changes in the microbiota and metabolism. https://t.co/6IS0OY5UeN

Seems to be at least an interaction in this space via dopamine ala mTOR acting as regulator."The mTOR inhibitor rapamycin has been shown to attenuate the behavioral effects of drugs of abuse, including cocaine." https://t.co/whDph4KGvQ

Oooh, I look. I type in about that dendritic spine phenomena and autism and the first link I click on in ddg mentions the role of mTOR. I have talents.https://t.co/rhJR4NHpfL https://t.co/AkRhbyPxfn
