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UltimApe@ultimapeover 6 years ago

Found studies exploring Buytrate's effect on Crohn's Disease that suggested it might be effective.Seems we may even know the method of action. https://t.co/rRuxtiRCmdMakes me wonder I wonder what is helping me. I don't get nearly enough SCFAs for it to be the cause?

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5/13/2019
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UltimApe@ultimapeover 6 years ago
Replying to @ultimape

"Gut microbiota produce butyrate by fermenting carbohydrates in a high fiber diet."But I'm doing a low carb diet. Whats up with that?https://t.co/xF1afbdWNw

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5/13/2019
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UltimApe@ultimapeover 6 years ago
Replying to @ultimape

Neat that carb fermentation may enhance sleep. That may be related to the memory protective effects we see when usying butyrate in alzhiemer's? There's some promise behind that as part of the inflammatory theory of Alzheimer's.https://t.co/SS1j2uuDP9

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5/13/2019
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UltimApe@ultimapeover 6 years ago
Replying to @ultimape

Maybe what i'm doing with my roughly keto diet is working on inflammation in the same as butyrate is working on people who ferment carbs?https://t.co/7cSBSI2RTp

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5/13/2019
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UltimApe@ultimapeover 6 years ago
Replying to @ultimape

I should explore the genes predisposing for better resistant starch digestion. I suspect I don't have them. Would explain why I struggled under a carb based diet, and also perhaps suggest a microbial avenue to go to help me deal with normal diets again.

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5/13/2019
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UltimApe@ultimapeover 6 years ago
Replying to @ultimape

It seems eating ghee might be giving me dosing of buytrate that I wasn't getting before. That would explain my overall mental clarity the past month despite trying to ruin myself thru sleep perturbation.

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5/13/2019
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UltimApe@ultimapeover 6 years ago
Replying to @ultimape

I also may be geting butyrate thru my normal milk based protein powder. Not producing it normally would explain why I can't seem to function well on 100% huel or soylent despite there being fermentatble source of fiber in them.

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5/13/2019
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UltimApe@ultimapeover 6 years ago
Replying to @ultimape

Ah also from my high fat yogurt. It seems that the progression of changes in my diet the past 6 months have been adding more and more external sources of butyrate accidentally. That might be what's going on despite not eating lots of fermentable carbs.

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5/13/2019
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UltimApe@ultimapeover 6 years ago
Replying to @ultimape

Whats the difference between sodium butyrate and beta-hydroxy butyrate?

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5/13/2019
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UltimApe@ultimapeover 6 years ago
Replying to @ultimape

ooh, this is actually part of a controversy eh?

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5/13/2019
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UltimApe@ultimapeover 6 years ago
Replying to @ultimape

"That is, amino acids from incompletely digested animal parts reach their colons and are fermented. In particular, in cheetahs, casein, collagen, and glucosamine have been shown to result in butyrate production comparable to fructo-oligosaccharides "https://t.co/1kmr9kBhVT

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5/13/2019
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UltimApe@ultimapeover 6 years ago
Replying to @ultimape

How do I test my poop for SCFA?

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5/13/2019
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UltimApe@ultimapeover 6 years ago
Replying to @ultimape

Taters going to tate. https://t.co/nITfhdCNhP

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5/13/2019
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UltimApe@ultimapeover 6 years ago
Replying to @ultimape

I wonder if "collagen, and glucosamine" fermenting into butyrate is partially why we see glucosamine and chondroitin helping improve joint health. If it's an inflammation related disorder associated with microbes...https://t.co/wFlqFWmvhN

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5/13/2019
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UltimApe@ultimapeover 6 years ago
Replying to @ultimape

I'm... going to guess that honey and honey bee gut bacteria promotes butyrate production and that butyrate producing microbes improve rheumatoid arthritis symptoms. 🐝Not going to bother looking that up right now, but leaving this here for future me.

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5/13/2019
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UltimApe@ultimapeover 6 years ago
Replying to @ultimape

Nice. https://t.co/dFTy4ZzfUe So has butyrate been proven to help diabetes in humans?

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5/13/2019
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UltimApe@ultimapeover 6 years ago
Replying to @ultimape

Is anyone testing this in humans?https://t.co/l5MndnyPQJ

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5/13/2019
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UltimApe@ultimapeover 6 years ago
Replying to @ultimape

This suggest the oddness of honey may be due to fructose, but apparently that is just a guess.https://t.co/VUFJHYJEzS

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5/13/2019
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UltimApe@ultimapeover 6 years ago
Replying to @ultimape

Could it be due to feeding butyrate producing bacteria?https://t.co/g0BxZ7OmPy

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5/13/2019
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UltimApe@ultimapeover 6 years ago
Replying to @ultimape

Apparently my girlfriend isn't type II diabetic enough to have health insurance pay for a continuous blood sugar monitor. Does anybody have notes on how to get one on the cheap (including the disposable testing bits)?

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5/13/2019
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UltimApe@ultimapeover 6 years ago
Replying to @ultimape

I'd love to see if adding honey and apple cider vinegar changes insulin response that coincides with an increase in butyrate producing bacteria strains.

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5/13/2019
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UltimApe@ultimapeover 6 years ago
Replying to @ultimape

Huh, they're only recently doing studies in mice in this space?https://t.co/a4kLWU8WB4

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5/15/2019
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UltimApe@ultimapeover 6 years ago
Replying to @ultimape

The niacin/butyrate receptor plays a role in cancer, huh.https://t.co/Qd6NiCHdpQ

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5/15/2019
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UltimApe@ultimapeover 6 years ago
Replying to @ultimape

I need to get a better source of niacin.

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5/15/2019
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UltimApe@ultimapeover 6 years ago
Replying to @ultimape

I wonder if the nicotine associated weight loss is thru the same channels that butyrate operates, that would put it in the same sort of position as CBD oil as I've layed out.https://t.co/USi0z5lp6T

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5/15/2019
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UltimApe@ultimapeover 6 years ago
Replying to @ultimape

it seems to have a similar style bimodal effect for how it affects insulin - increase insulin resistance in non resistant mice, but reduces it in insulin resistant mice. https://t.co/1BUvV3SXT0

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5/15/2019
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UltimApe@ultimapeover 6 years ago
Replying to @ultimape

I wonder if nicotine would help with my sleep/wake issues?https://t.co/KAcvcgfosH

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UltimApe@ultimapeover 6 years ago

Would be interested in a nootropic based approach if someone has experience with that and fighting 'non-24' disorders. I've had some luck with cbd oil to help me sleep, but it's my waking up rhythms that I'm struggling with.

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5/15/2019
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UltimApe@ultimapeover 6 years ago
Replying to @ultimape

Old people need more SCFAs and to be less lonely.https://t.co/yvs1hE3DGUhttps://t.co/yEhyjxrpWF

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UltimApe@ultimapeover 6 years ago

social stress -> immune system -> social behavior. This is a feedback loop.Mmm butyrate. https://t.co/VAkuyH8Cq9

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5/20/2019
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UltimApe@ultimapeover 6 years ago
Replying to @ultimape

Vim & Vigorhttps://t.co/x9jacivm59

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UltimApe@ultimapeover 6 years ago

Aging is a lie?https://t.co/21Gm34EbzY

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5/20/2019
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UltimApe@ultimapeover 6 years ago
Replying to @ultimape

"chronic inflammation may represent the trait d’union of microbial alterations and the development of muscle-wasting conditions in advanced age through a gut microbiota-muscle crosstalk. [...] players involved in this process are not yet fully understood."https://t.co/x6ha3dGvOb

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5/20/2019
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UltimApe@ultimape6 months ago
Replying to @ultimape

Daddy, would you like some sausage?https://t.co/j7mK8fJX3B

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UltimApe@ultimape6 months ago

Wake up babe, new paper on longevity just dropped> "over 200 octogenarians [...] revealing a decline in gut bacterial diversity with age, particularly the loss of Faecalibacterium prausnitzii, which produces butyrate—a key compound for gut health" https://t.co/4TIRREhMo7 https://t.co/7GZ8MyPbpm

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3/13/2025
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UltimApe@ultimape6 months ago
Replying to @ultimape

What kind of sausage reverses stroke?https://t.co/FkVCi8OsCO

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3/13/2025
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UltimApe@ultimape6 months ago
Replying to @ultimape

Baby poop sausage lmao. > "Cell-Free Supernatant of Lactobacillus rhamnosus and Bifidobacterium breve Ameliorates Ischemic Stroke-Generated Neurological Deficits in Rats" https://t.co/WA1u6qtmmW

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3/13/2025
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UltimApe@ultimape6 months ago
Replying to @ultimape

I bet we could get FMTsfrom celebritiesand use it to cure diseaseOh my god, please.https://t.co/h2ajNxaMtq

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UltimApe@ultimapeover 1 year ago

@LoCtrl @0x49fa98 @eigenrobot What if we spike fermented meats with celebrity poop?https://t.co/faUgCfGU7y

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3/13/2025
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UltimApe@ultimape6 months ago
Replying to @ultimape

The spice must flow.https://t.co/Qa6WR87X4q

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UltimApe@ultimapealmost 3 years ago

I made a joke a while back about getting access to Tom Brady's shit. But I wasn't joking. His work to get healthier despite R.A. Symptoms may mean his gut bacteria holds a cure. The Spice must flow! https://t.co/Aa2H7hP0oh

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3/13/2025
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UltimApe@ultimape6 months ago
Replying to @ultimape

So, you want to be a leader of men?https://t.co/harzgeHrVz https://t.co/jNhl4W1eix

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UltimApe@ultimapeabout 1 year ago

@sakiwebo @Mangan150 @drmikehart This I why I think it would be neat to get tom brady's poop sampled."The increased ratio of pathogenic to commensal bacteria in the gut after trauma is thought to encourage the progression of post-TBI disease severity" https://t.co/On2TLozCYJ

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3/13/2025
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UltimApe@ultimape6 months ago
Replying to @ultimape

"For your information, this is me being creative."https://t.co/ZrGz10Rukh

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3/13/2025
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UltimApe@ultimape6 months ago
Replying to @ultimape

"I am not a leader of menSince I prefer to followDo you think I could have a drinkSince it's so hard to swallow?So hard to swallow" 🎶https://t.co/dz5NrLNztDhttps://t.co/IBE9DzsPCV

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UltimApe@ultimapeabout 3 years ago

@Charliecross @sadalsvvd The poop it self probably does just as much in this space given that healthy gut bacteria seem to hit on mTOR and serotonin pathways similar to the mushrooms :3Amazing how many ancient medical rituals involved purified feces.

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3/13/2025
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UltimApe@ultimape6 months ago
Replying to @ultimape

Creativity is hard, lets eat sausages.https://t.co/2PsaZJS5YL

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UltimApe@ultimape6 months ago

I accidentally words.I should accidentally some salt in this mix to promote bile production in the process.https://t.co/ccJWL3kUVL

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3/13/2025