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🧵 Thread (14 tweets)

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vitalik.eth@VitalikButerin• about 10 years ago

AI: the subset of informatics we have not yet figured out and renamed to something else. Aging: the subset of disease we have not yet...

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12/5/2015
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UltimApe@ultimape• almost 5 years ago
Replying to @VitalikButerin

@VitalikButerin I figured it out and renamed it incomplete human hibernation.

0 1
2/3/2021
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UltimApe@ultimape• almost 5 years ago
Replying to @ultimape

@VitalikButerin Ya'll got any of them SIRTins?https://t.co/V5jGKAGAVthttps://t.co/vmCPGzsJ9o

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UltimApe@ultimape• about 5 years ago

Huh.Estrogen and Resveratrol impact SIRT1 expression and modulate vascular smooth muscle tissue. https://t.co/zNUUqcKXYQWhich plays a role in heart disease.https://t.co/77ivJuxt9BVia microbiota?https://t.co/08XGaqOXjJ

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2/3/2021
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UltimApe@ultimape• almost 5 years ago
Replying to @ultimape

@VitalikButerin "and you don't seem to understand" 🎶https://t.co/9J2YHJGcKF

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UltimApe@ultimape• over 5 years ago

@balajis @The_Lagrangian @almostlikethat And all of that is hit with SIRT1https://t.co/eYIwCy98Mnfunny thing about SIRT1 is the guy who discovered it's role in longevity is to occupied with genetics and doesn't even look at bacteria.https://t.co/gAQF3vRSPp

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2/3/2021
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UltimApe@ultimape• almost 5 years ago
Replying to @ultimape

@VitalikButerin Did you know that I predicted Parkinson's & Alzheimer's as being tied to the gut at about 3 years before anyone was really beginning to study it?https://t.co/EiRIaqEta3

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UltimApe@ultimape• almost 5 years ago

@NotGyro @Rainmaker1973 @MeFromBefore If so, we might be able to take all of this and use this idea to fix age related disease. https://t.co/ABqQq2o7dF

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2/21/2021
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UltimApe@ultimape• over 4 years ago
Replying to @ultimape

@VitalikButerin Vitalik plz. https://t.co/NGSl1qFZCx

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UltimApe@ultimape• over 4 years ago

DO YOU EVER DISAGREE WITH ONE OF THE LEADING FIGURE HEADS OF ANTIAGING RESEARCH? and can cite sources about why he's dumb?https://t.co/5zcaRkieDk

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5/17/2021
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UltimApe@ultimape• over 4 years ago
Replying to @ultimape

@VitalikButerin I am insane>https://t.co/ZtjK7fCU7z

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UltimApe@ultimape• almost 5 years ago

Talking to a bunch of smart people in a slack group about my ideas on human hibernation. https://t.co/gUnnJSt52f

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5/17/2021
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UltimApe@ultimape• over 4 years ago
Replying to @ultimape

@VitalikButerin I have been exploring this space of ideas non stop for the past 5 years.https://t.co/r6wvetz4aD

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UltimApe@ultimape• over 4 years ago

Fasting -> Inhibits mTORFasting -> lipid metabolism regulationFasting -> P-Glycoprotein expression changesFasting -> Immune system shiftsFasting -> Blood Brain Barrier function + toxin clearance.Fasting -> Better Intestinal barrier functionFasting? Nah. Acute Aestivation. https://t.co/RWydlod7x9

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6/17/2021
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UltimApe@ultimape• over 4 years ago
Replying to @ultimape

@VitalikButerin Please, listen.https://t.co/zPfNg62jOJ

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UltimApe@ultimape• over 4 years ago

I litterally I go looking for things my predictions make. Like fertility and telomere length ought to be tied to factors around hibernation. and find that scientists are surprised by it. 😹https://t.co/uSQdyBb9qk

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7/12/2021
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UltimApe@ultimape• over 4 years ago
Replying to @ultimape

@VitalikButerin You might be interested in this. I saw @juanbenet was one of the donors. https://t.co/9GKIKpRYfn

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Ryan O'Shea@Ryan0Shea• over 4 years ago

Excited to highlight the work of @MartinBJensen, the Longevity Apprentices, & of course the donors. If you know of a researcher that could use a bit of the $26 MILLION in funding just made available, let them know about this!

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9/13/2021
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UltimApe@ultimape• about 4 years ago
Replying to @ultimape

@VitalikButerin @juanbenet I'm going to perform miracles. It's funny.https://t.co/bF2PavKazD

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UltimApe@ultimape• about 4 years ago

@balajis @The_Lagrangian @almostlikethat Did you catch the part where I reverse engineered how eating ants mixed with garlic oil and some dirt + mushrooms extracted with an ancient golden drink could lead to wound healing via augmentation of commensal gut bacteria?https://t.co/ZleQItHBIy

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9/25/2021
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UltimApe@ultimape• almost 4 years ago
Replying to @ultimape

@VitalikButerin @juanbenet I somehow suddenly reversed my effective age by 10 years by eating literal dog shit. Get on my level. https://t.co/sxktFVh3Yi

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UltimApe@ultimape• almost 4 years ago

Got my after @MyViome sample.Now up at https://t.co/wYtHF5Zvxu It worked! I went from 37 years old to 27 years old according to measure of IGF-1, mTOR, sirtuins, and AMPK.How bout them apples.https://t.co/0OKR4zKAn4 https://t.co/LYUqmtuu7X

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3/14/2022
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UltimApe@ultimape• about 3 years ago
Replying to @ultimape

@VitalikButerin @juanbenet Thank you.https://t.co/5NxfoSUChh

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UltimApe@ultimape• about 3 years ago

"We found evidence for multiple mechanisms that we know are linked to PD, but we didn’t know they were happening in the gut also and are orchestrated by the microbiome" [December 1, 2022]https://t.co/YdZhfjeyqV🤔🤫😇https://t.co/qWUdOUttHr

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12/2/2022
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UltimApe@ultimape• about 3 years ago
Replying to @ultimape

@VitalikButerin @juanbenet Gonna be able to perform a miracle thanks you taking a risk on me.https://t.co/6CMMF0JOQ9

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UltimApe@ultimape• about 3 years ago

If it works on my mom, I will hopefully be able to figure out what bacteria metabolites are missing and figure out how to help my vegan gram walk again.https://t.co/qCpM47W7fD

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12/2/2022