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🧵 Thread (13 tweets)

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UltimApe@ultimape• almost 3 years ago

Have you ever tried to fix your lipid signaling game via gut bacteria, so your body can produce SCFAs and digest omega fatty acids to better produce endocannabinoids and combat inflamamtion... And then suddenly all your health problems just disappear? https://t.co/l9WQjcM4Go https://t.co/lFxq0kgsn1

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UltimApe@ultimape• over 5 years ago

Fasting has been shown to improve viral infection outcomes.Cold has been shown to improve viral infection outcomes.Fasting leads to 2-AGTRPM8 activation leads to 2-AG2-AG hits CB1 and CB2, acting to down regulate IL-6IL-6, left unabated? rampant inflammation.

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12/12/2022
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UltimApe@ultimape• almost 3 years ago
Replying to @ultimape

I can't stop thinking about how different activation of CB1 and CB2 end up driving the liver and brain to regenerate. It's like they have to fight over limited resources, so respond to circadian rhythm signals from gut to control synchronization.https://t.co/AoNkZAgmzq

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12/12/2022
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UltimApe@ultimape• almost 3 years ago
Replying to @ultimape

It's almost like I could predict that toxins that develop in the brain while it is active during the day need to be worked on by the liver while you sleep, so the body redirects healing factors to mitigate damage. https://t.co/f3TsWjOfw0

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12/12/2022
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UltimApe@ultimape• almost 3 years ago
Replying to @ultimape

Funny how all of these lipid signaling processes end up impacting the immune system's role in liver regeneration. It's almost like I figured out how to reverse aging with it :3https://t.co/dPhSDHfU1Y

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12/12/2022
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UltimApe@ultimape• almost 3 years ago
Replying to @ultimape

Friend told me her dead necrotic ovaries regenerated. She was doing a lot of cannabis and acting on her serotonin system to mitigate a lack of an intestine.So what if I make my intestine do that, can I trigger regeneration?https://t.co/7Ft5XZ9j62

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UltimApe@ultimape• over 3 years ago

Brb, looking up spontaneous regeneration of ovaries after dog is spayed.Do you think I can have a spayed dog give birth to a mythic two headed beast?I bet I can.https://t.co/lok4j5AbtO https://t.co/RDw3SswMmx

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12/12/2022
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UltimApe@ultimape• almost 3 years ago
Replying to @ultimape

Baby shark.. doot doot doot doot.https://t.co/JrzUauLCaG

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12/12/2022
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UltimApe@ultimape• almost 3 years ago
Replying to @ultimape

Waving a towel at the sharks, screaming a them "DO YOU WANNA GET HIGH?". But they don't come ashore because they know I am actually talking about lipid function in limb regeneration. https://t.co/PbKCerMes6

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UltimApe@ultimape• over 3 years ago

Lateral thinking is a hell of a drug.https://t.co/sxXH6mC8xl

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12/12/2022
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UltimApe@ultimape• almost 3 years ago
Replying to @ultimape

Darwin had his wife play the piano to worms because they were curious if they would crawl out of the ground, cuz he heard a rumor about worm grunting.https://t.co/W5Y2Xt3g8b

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UltimApe@ultimape• over 3 years ago

"essentially a genius, who looked at the same facts as others but because of his prodigious powers of creative thinking, he was able to ‘break the set’ of previous assumptions and combine the data into a new and coherent pattern." https://t.co/g78ZSRODzWhttps://t.co/lR4smTbfRf

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12/12/2022
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UltimApe@ultimape• almost 3 years ago
Replying to @ultimape

I like to think about science like David bowie thought about making music. https://t.co/itoiaEtgm2

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UltimApe@ultimape• almost 5 years ago

"It’s almost like a technological dream in its own way. It creates the images from a dream state without having to go through the boredom of going to sleep all night; [...] And it will give me access to areas that I wouldn’t be thinking about otherwise…" https://t.co/g9vhuV9vOJ

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12/13/2022
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UltimApe@ultimape• almost 3 years ago
Replying to @ultimape

Please wake up. Shake the world.https://t.co/sfnzMCtQyV

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UltimApe@ultimape• about 4 years ago

Have you tried not being in a state predisposed toward hibernation?https://t.co/C39wTvPGUr

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12/13/2022
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UltimApe@ultimape• 5 months ago
Replying to @ultimape

> "The reset strategy sidesteps the immense difficulties of precise diagnosis and repair by embracing a radically different approach: wholesale abandonment of the problematic state."https://t.co/ZAMW3kMMdIhttps://t.co/DsXgMqdLNW

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4/19/2025
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UltimApe@ultimape• 5 months ago
Replying to @ultimape

Have you tried resetting the body's biological state by turning the gut off and on again, so you generate more pluripotent cells like in your youth? https://t.co/ai3nWoDekD

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UltimApe@ultimape• 5 months ago

"her genes, microbiome, and lifestyle reveals that Branyas’s cells functioned as if they were 17 years younger than her chronological age. Her gut microbiome, strikingly, resembled that of an infant."https://t.co/EZH5daAKdD (h/t @docmmiller on linkedin) https://t.co/riAjRY0xxv

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4/19/2025
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UltimApe@ultimape• 5 months ago
Replying to @ultimape

What is a body without organs anyway?https://t.co/B7eaJL8xZd

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UltimApe@ultimape• almost 4 years ago

Reset the state. Regrow the organ.Have you tried turning the spikey rodent signaling pathway off and on again?https://t.co/g8ISZaJQYy https://t.co/sjbVh7Prhv

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4/19/2025