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P.D. Mangan Health & Freedom Maximalist πŸ‡ΊπŸ‡Έ@Mangan150β€’ 5 months ago

Calorie restriction (CR), long studied for lifespan extension, seems only to work by preventing obesity. Chart shows the degree of lifespan extension is proportional to the degree different breeds of mice gain weight when fed normally. So, CR may only be normalizing lifespan, not really extending it, in domesticated animals that gain weight with age. However, humans are domesticated animals with a tendency to gain weight with age, so staying lean can normalize lifespan, increase healthspan, and prevent chronic diseases of aging. PMID: 24941891

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4/5/2025