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David Perlmutter, MD@DavidPerlmutter• 8 months ago

This might be controversial, but the carnivore diet is missing an essential component to your health and longevity: FIBER Fiber is associated with a lower risk of type 2 diabetes, Alzheimer’s & certain cancers. Bottom line: You need fiber.

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3/4/2025
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UltimApe@ultimape• 8 months ago
Replying to @DavidPerlmutter

@DavidPerlmutter Organ meats can ferment into the SCFAs that plant fiber ferments into.The main heart healthy SCFA made by plants that everyone talks about when they do research on fiber is literally named after butter. NAMED AFTER BUTTER.

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3/4/2025
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UltimApe@ultimape• 8 months ago
Replying to @ultimape

@DavidPerlmutter I eat more plant fiber than you right now BTW. My diet last month was like 40% food meant for gorillas. literally

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3/4/2025
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UltimApe@ultimape• 8 months ago
Replying to @ultimape

@DavidPerlmutter I cured my GF's type II diabetes using fermented dairy.

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3/4/2025
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UltimApe@ultimape• 8 months ago
Replying to @ultimape

@DavidPerlmutter You don't need fiber. You need bioavailable nitrogen sources that gut bacteria can use to promote healthy anti-inflammatory SCFA production chains.

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3/4/2025
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UltimApe@ultimape• 8 months ago
Replying to @ultimape

@DavidPerlmutter Reduce the risk of Alzheimer's by promoting gut health.> "In conclusion, we show that kefir in natura, as well as its fractions may be promising therapeutic source against AD, modulating amyloidogenic related pathways."https://t.co/pLbIKrmoGEhttps://t.co/VcyTCVYAYi

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UltimApe@ultimape• 9 months ago

But we stopped doing FMT trials for Alzheimer's because SARS-COV-2 showed up in poop and the clinicians didn't want to risk it.https://t.co/pH322GIOhd

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UltimApe@ultimape• 8 months ago
Replying to @ultimape

@DavidPerlmutter If you're doing a carnivore diet, you'll get more than enough SCFAs sources to neutralize circulating TMAO. If you aren't, explore removing sources of excess nitrates and eat more collagen sources to promote healthy NO recycling thru improved gut mucus.https://t.co/ceYC50fBL7

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3/4/2025
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BioBoost@BioboostDaily• 8 months ago
Replying to @ultimape

@ultimape @DavidPerlmutter Probiotic rich foods like kefir are great as is sauerkraut, but it’s maybe not a great blanket statement, some people don’t tolerate dairy well and may invariably make gut issues worse dairy based probiotic rich foods.

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3/4/2025
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UltimApe@ultimape• 8 months ago
Replying to @BioboostDaily

@BioboostDaily @DavidPerlmutter use water kefir.Or seek out goat/sheep milk if you struggle with casein sensitivty, they hit different.Kefir cured my lactose intolerance! There's also work being done to use microbes+butyrate to reduce allergy to cow's milk.https://t.co/QyS8unZyAi

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3/4/2025
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UltimApe@ultimape• 8 months ago
Replying to @ultimape

@BioboostDaily @DavidPerlmutter There's also Ghee, which if you make your own, you can get to be casein free (Some store stuff adds cream back in). Fermented Cultured Butter turned into a ghee is a great way to get a ton of health stuff besides concentrating the butyrate. https://t.co/JMVoH3Y8Ik

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UltimApe@ultimape• 8 months ago

@Mangan150 Ghee made from cultured butter sources seems ideal, but we are losing out on these practices.Ayurevedic Ghee has been using this tradition for years and years, but it is largely dismissed.https://t.co/3aedz7gj9QTime to buy a butter churn? 😉

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UltimApe@ultimape• 8 months ago
Replying to @ultimape

@BioboostDaily @DavidPerlmutter That thread talks about the fatty acids as potent HDAC inhibitors, which are partly how fiber being fermented into fatty acids helps fight cancer. https://t.co/PkRWPYsfAA

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UltimApe@ultimape• 8 months ago

@Mangan150 Most of these are classified as HDAC inhibitors and seem to be fixing gut damage.https://t.co/roKez3gyCa

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UltimApe@ultimape• 8 months ago
Replying to @ultimape

@BioboostDaily @DavidPerlmutter We can get these in us a number of ways, fiber is just one vehicle for microbse to produce the chemicals for us.Saurkraut is great, the fiber is pre-digested by the fermentation. Fermentation was the only way i could eat plants for years due to Crohn's issues.

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3/4/2025
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UltimApe@ultimape• 8 months ago
Replying to @ultimape

@BioboostDaily @DavidPerlmutter The same "blanket statement" issue shows up with plant fibers. We even see examples in literature where apples screw people up because of pectin intolerance from missing microbes. https://t.co/Ebu7azUit6

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UltimApe@ultimape• about 1 year ago

Neat"Regarding SCFAs, acetate levels rapidly increased with incubation with pectin, and butyrate levels also increased after 6 h of incubation. The results suggest that pectin fermentation increases bacterial species belonging to Clostridium cluster XIV" https://t.co/EKWq4YctKS

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3/4/2025
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UltimApe@ultimape• 8 months ago
Replying to @ultimape

@BioboostDaily @DavidPerlmutter Many high fiber plants also are loaded with fructans, it's highly likely that people are missing gut bacteria that can digest that as well.https://t.co/gLBXapaib8

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3/4/2025
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UltimApe@ultimape• 8 months ago
Replying to @ultimape

@BioboostDaily @DavidPerlmutter Dairy is an interesting example, if you stop eating dairy for a while, the bacteria that digest lactose can die off. Many "food elimination diets" like FODMAP probably induce intolerance by starving & killing those bacteria!https://t.co/dh0MJgrVt2

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UltimApe@ultimape• 12 months ago

@_Illegible @nosilverv @AlmothanaAlt I think its hilarious that people test their lactose intolerance by abstaining from dairy products and end up likely starving off bacteria needed to digest it. Then conclude they must be lactose intolerant.

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3/4/2025
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UltimApe@ultimape• 8 months ago
Replying to @ultimape

@BioboostDaily @DavidPerlmutter Not to mention antibiotic induced intolerances are common.> "Early-life exposure to antibiotics appears to be related to an increased risk of allergic symptoms of hay fever, eczema, and food allergy later in life." https://t.co/eAveqrCDlUhttps://t.co/XZVZ6oEqeB

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UltimApe@ultimape• over 3 years ago

"We matched 500,647 antibiotic nonusers to 500,647 antibiotic users in the Medicaid pediatric population.[...]Compared with antibiotic nonusers, children with antibiotic prescription had an increased risk of food allergy." https://t.co/GyJYgXWOgg

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UltimApe@ultimape• 8 months ago
Replying to @ultimape

@BioboostDaily @DavidPerlmutter I even found some bacteria that denature/degrades the Casein.You can tell it's being degraded because the whey/fat/protien in the yogurt/kefir starts separating (Casein is the emulsifier that presents this).Huge potential, understudied.https://t.co/85WAnXOTie

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UltimApe@ultimape• almost 3 years ago

@keller_via @embryosophy @DesidErratum This also stands out as interesting... a strain of Lactobacillus animalis can convert some casins into an ace inhibitor? 🤔 That would work great for my gut. https://t.co/W80g8FXYgC

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