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🧵 Thread (7 tweets)

Science Banana@literalbanana• 11 months ago

"okay I know it sounds crazy but imagine: we give fruit flies magic mushrooms and SSRIs to decrease their depression and measure it with a forced swim test" https://t.co/c8lpwla9HV https://t.co/e6QXFJkRNF

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UltimApe@ultimape• 11 months ago

Replying to @literalbanana

@literalbanana Inb4 it doesn't work as well if they don't account for gut environment and diet.https://t.co/XV3kLZ2w6a

UltimApe@ultimape• over 1 year ago

There's more than one way to fix the gut.https://t.co/46Z3kbI9yY https://t.co/WmEX6QHZoj

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UltimApe@ultimape• 11 months ago

Replying to @ultimape

@literalbanana In the human gut, it takes a couple of days for colonies to grow and abate. Most of the ones in our gut have a 3 day lifecycle, so the 2-day old flies may be missing significant impact entirely.

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UltimApe@ultimape• 11 months ago

Replying to @ultimape

@literalbanana Given psilocybin's activity on serotonin signaling, we should expect the gut to be a big player here. Alas, we killed the ones that may be in the process of a gut problem.https://t.co/hcWywiyFP2

UltimApe@ultimape• about 3 years ago

@DrJackKruse We can study ROS production of Drosophila and it's response to gut pathogens, their role in harvesting energy."Serotonin modulates insect gut bacterial community homeostasis"https://t.co/CyKb7SaaE9We may be seeing same in humans ala stuff like this:https://t.co/rmqTEPQhQM

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UltimApe@ultimape• 11 months ago

Replying to @ultimape

@literalbanana Gonna go see if fruit flys fart, bye!

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UltimApe@ultimape• 11 months ago

Replying to @ultimape

@literalbanana Grok seems to hallucinate science studies even when in deep search mode. But Interesting results none-the-less.https://t.co/s60Hog3faN

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Sichu Lu@lu_sichu• 11 months ago

Replying to @literalbanana

@literalbanana the consolation of philosophy but stoicism for flies

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