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They make an -amab that targets VEGF-A? Thats neat. I bet that combines well with the FGF ones. https://t.co/hELlMtRkpi https://t.co/3RWP42X3lN
I'm doing the complete opposite via gut bacteria targeting of IFN‐γ, Gli1, and Sirt1 to regulate and maintain neurogensis+vsacularization to recover from demylination. https://t.co/dB93a6g8xBJaking my stats, you see...https://t.co/QToVMpK3Pg
It seems to me that antibodies to a particular growth factor may backfire if not dosed well. I'd rather use my immune systems's native inhibitors and leverage homeostasis to regulate it in a balanced way.But I can see the need if the cancer is real bad.
There's a million of these things when you consider all the biosimilar ones on the market. https://t.co/so2KTDpCBm https://t.co/hDEtWgGZ9y
I don't envy a doctor trying to figure out the matrix of side effects and interactions across all these alphabet soup of anti-vegf -amabs. Thankfully the rules are in place to make this easier to disambiguate.https://t.co/smJSeihMnqhttps://t.co/4ixECAkpCJ https://t.co/lLRleckDNy
Infliximab-cock sounds kinda funny tho. I wonder if that is valid? Technically speaking... we could see medical trials of using some variation on it to treat Erectile Dysfunction.https://t.co/SGUb2GjarQ (if we haven't already)https://t.co/4yTjpsvKBv https://t.co/NvRFk3PpMl
That's right, my autistic ass thinks these drugs can make big pp.https://t.co/ieIw5bOTAU
@JohnnyB_avo @fire__exit Huh, space is ripe for intrigue. it seems are a bunch of "biosimilar" TNF-α blockers being pushed thru FDA. Inflectra (infliximab-dyyb) and AVSOLA (infliximab-axxq) etc.https://t.co/3xnG49e3SVI wonder how long until it's tried for PTSD or Autism.https://t.co/JHH3gzzpCq
Gonna find me a plant that acts to inhibit VEGF-A and tell my mom to use it to fight her uterine cancer if she gets it again.https://t.co/IW9c8aOJuk
@JohnnyB_avo @fire__exit If only there was some kind of plant, used for centuries to treat GI issues, known to inhibit TNF-α https://t.co/BXjgxhPpiY and possibly even reversing crohn's related gastrointestinal distress https://t.co/8dQtzC5o4CShame it doesn't exist.
A plant for every combination of FGF? That might be a bit tricky.https://t.co/8EMy5v5JMD
Don't get me started on curing erectile dysfunction using gut bacteria."Long-term use of dulaglutide might reduce the incidence of moderate or severe erectile dysfunction in men with type 2 diabetes."https://t.co/YfUKHbhhtMOf course it does.https://t.co/TXxEw21CWF
All this alphabet soup stuff makes me hard."Glucagon-like Peptide-1 improves proliferation and differentiation of endothelial progenitor cells via upregulating VEGF generation"https://t.co/BUujqJx4La
"Dick's never been harder and my grips never been stronger." https://t.co/nC1juxSpQ9
it's all very simple really...https://t.co/ovWsjpr5vQ
@statto @Grimhood @LevPo Having the body regulate metabolites internally thru feedback from the immune system and homeostatic processes that control gut bacteria? It is going to work better than blindly dumping in some pharmaceutical drug in a pill. https://t.co/vSH4BBZFc1
We create these complicated markets and approvals for single activity antibodies and then dump them into the system without really thinking about the side effects. Seems kinda silly.But hey, I'm not a doctor. What do I know?https://t.co/YU5yeaDHCq
Sorry for being snarky. My GF has a thrush flair up again after catching covid and its reminding me of how her lung medication gave it to her last time.Thankfully this time it's not causing her 180/96https://t.co/clKrddZw6C
Doctor at ER told me that the photos I took of Candia wasn't candida, and then told me that the risk of her dying from it wouldn't happen unless she was immune compromised.We went to ER because of her having a Hypertensive crisis + her candida flaring back up before her menses. https://t.co/IyLEnNql6P
This is weirdly connected to the VEGF-A / FGF2 thing because candida manipulates these growth factors to promote blood vessels to feed them. They're nasty little shits.https://t.co/hUElAnBJ3K
It's all frosted butts and and weird ass dicks to me.https://t.co/rzct9PqEeQ
What if I told you that all of this research is promulgated on a hypothesis that I can cure my girlfriend's type 2 diabetes thru diet by using various terpenes to bias her microbiome... and all this about dicks is proxy research to hormone-microbe ties.https://t.co/zZ9obc2BGY
Cancer is a Dick. The biggest dick."The Bacteria That Help Bears Hibernate Could Help Cancer Patients" https://t.co/Wtg4UBsfpf
Fuck cancer before it can fuck you.https://t.co/yrxAHHg48n
If you can find a good doctor who can understand this stuff hard stuff and help you work thru dosing it, they are worth their weight in gold. https://t.co/UiusddaxmE
Good luck trying to pay for it out of pocket.https://t.co/H069Y2GY4j https://t.co/B8ddlf66QL
Anyway. My dad now has locked-in syndrome from his second stroke absolutely fucking his brainstem. I'm trying to figure out how to regrow blood vessels and encourage neurogenisis. That's why I'm here... looking at tweets / shitposting about vascular aspects of cancer & muh dick.
Hey, could be worse. Have a picture of my dad's dog.https://t.co/3aGJfhtBp5He will never be able to pet him again if I can't figure this out.So what else stops cancer vascularization and how can we do the opposite?Also, what kind of dog is this? Some kind of shit-poo mix. https://t.co/mSQ8xxzGOv
But hey! silver lining is i'm one step closer to completing my collection of books by David Macaulay.There's some great diagrams about the brain in it. I realized I didn't have a good anatomy book yet and I saw "The way we work" as a used/clearance book at @NorthshireBooks https://t.co/tIfHjU3zmy
Is that an engorged Medulla Oblongata in your pocket, or are you just happy to see me?https://t.co/dzelH35toc https://t.co/C77JJg9XkU
"I knew nothing when I startedI didn't have any idea what the main questions wereI had no sense of what the goal of the book would bdI just knew that through the experience I would learn about myself"https://t.co/y7Osh9MQyn
Study hard what interests you, even if it involves throwing shit against the wall.https://t.co/cs2HU1oJO5
"I finally figured out what all those different shaped tanks do! [...] I mean digesters... what a fantastic life for bacteria: To be flung against the walls endless in this stream of sewage. I mean its a spa, for very tiny creatures, in a way... " – David Macaulay😍
Oh. So. If someone has a feeding tube, what's the best way to introduce pre/probiotics?https://t.co/Qbb3yCf8dZ
"bad ideas make me want to throw up" 🦆https://t.co/MtqDFW4Pyj
Ah, @biohacker just reminded me about pu-erh's impact on gut health.Looking it up, it may be possible to use coffee/tea thru a tube feeder? That is interesting.https://t.co/fLJCY5bqMohttps://t.co/JTDZmswCKN
"Qi deficiency and blood stasis""The role of JAK/STAT signaling pathway in cerebral ischemia-reperfusion injury and the therapeutic effect of traditional Chinese medicine: A narrative review" [NOV 2023]https://t.co/zEMXIaerPyhttps://t.co/l8wcYjXLcQ
hmm. If I wanna get teh blood flowing, I should focus on angiogenesis.Pu-erh helps gut health in part by helping increase butryate.And well... "GPR43 regulates sodium butyrate-induced angiogenesis and matrix remodeling" [2021]https://t.co/uC5G3jbTKe
Oh, it's that thing again, GPR43. I know this.https://t.co/TpOSohUuzS
@bigmeedicine If you try ice cream before bed, watch out for emulsifiers that dysrupt mucus. And avoid Carrageenan, it kills a bacterium in the gut that augments production of SCFAS that aid in GPR41 GPR43 related anti-inflammatory responses. https://t.co/ilrmroLabg
It's funny to me how pu-erh helps mice resist blue light, and that it might be via butyrate.Do you think if I increase my dad's butyrate, he'll be better able to heal?https://t.co/04MOZnk66q
Nobody here but us chickens."Butyrate may act as one of the signals to mediate blue-light-induced small intestinal development and mucosal barrier integrity enhancement and promote cell proliferation via the GPR43/Gi/PI3K/AKT/p-GSK-3β/β-catenin pathway."https://t.co/gWctmL6mxd
I wonder what a good source of magnesium is for tube-feeding replenishment.https://t.co/6HrDqeujls
Put that dawg in you.https://t.co/RYSNGDDsbX
@no_identd @Valuable @_ali_taylor Chelating heavy metals out of my system is one of the things I have been trying to fix because I grew up in the wash water of a superfund site. The copper load probably messed me up. Now I got that dawg in me.https://t.co/vBPJAfOIVxhttps://t.co/WIpqAzfWLO https://t.co/vWc6MHzbqM
I love you dad. I woke up seeing your face again today.https://t.co/Fz4uX2mHth
I don't like seeing you in pain. So I'm pretending I'm talking about walruses to you.And by that I mean, imagining making my dad laugh, the bad memory of him isn't so bad. https://t.co/31RT2uJdSK
