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Georgi D.@haidut• over 1 year ago

Niacinamide may treat post-orgasmic illness syndrome (POIS) [https://t.co/DvgmzwpsyF] #energy #mitochondria #nad #niacinamide #nicotinamide #POIS #reproduction #VitaminB3 #raypeat #idealabs #idealabsdc

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8/25/2024
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Mineral Chief@MineralChief• over 1 year ago
Replying to @haidut

@haidut You ever heard of minerals? The number one thing MISSING in our food supply!? Sometimes i wonder if your a big pharma psyop. The top ten minerals, start there. Once you figure out iron deficiency is a myth you will understand.

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8/26/2024
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UltimApe@ultimape• over 1 year ago
Replying to @MineralChief

@MineralChief @haidut Tell me what minerals improve gut health in a way that supports mucus production by goblet cells to allow for akkermancia muciniphila and I'll tell you what minerals are missing for the native production of niacin by gut mcirobes.

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8/27/2024
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UltimApe@ultimape• over 1 year ago
Replying to @ultimape

@MineralChief @haidut I fixed my GF's iron deficiency by giving her kombucha. Turns out you kinda need healthy bile acid function (tied to FXR signaling by gut bacteria) and healthy metalthionines (tied to B vitamins made by gut bacteria) to absorb those minerals you speak of.

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8/27/2024
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UltimApe@ultimape• over 1 year ago
Replying to @ultimape

@MineralChief @haidut Did you know thyroid controls mineral absorption too? It's fascinating, there is a feedback loop between mineral supply and thyroid function. So fixing thyroid can address mineral imbalance and vice versa. https://t.co/mkKFDVkKEF

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8/27/2024
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UltimApe@ultimape• over 1 year ago
Replying to @ultimape

@MineralChief @haidut Bioavialibility and using up minerals for various processes is just as important as having enough.I have successfully predicted the outcome and shifts of my GF's mineral tests on multiple occasion. These thing are all interconnected.

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8/27/2024
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Mineral Chief@MineralChief• over 1 year ago
Replying to @ultimape

Zinc, Selenium, Iron and Magnesium... are important for goblet cells.. And the proper metabolism of vitamin A is needed for goblet cells. Iron is easily acquired from not fortified dietary sources. One should never supplement iron. Copper helps with proper iron transport and metabolism. I wonder if those with better mineral proficiency and vitamin A metabolism have more akkermancia? 4 minerals are decently important for native production of niacin by gut bacteria.

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8/27/2024
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UltimApe@ultimape• over 1 year ago
Replying to @MineralChief

@MineralChief @haidut Good answer. I eat oysters for zinc, Garlic for Selenium, Blackstrap Molasses for Iron and Dark Chocholate for Magnesium. I depend on kefir to help my body produce the right kind of bile to aid in metalthionines and they turn the dairy into sugars that feed Akkermancia as well.

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8/27/2024
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UltimApe@ultimape• over 1 year ago
Replying to @ultimape

@MineralChief @haidut GF was supplementing 1000% of iron when the doctors told her she was low. I started giving her kombucha and we cut all the supplementation. Suddenly she no longer has anemia.I suspect much of the iron was being used up by pathogenic biofilm formation in the gut.

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8/27/2024
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Mineral Chief@MineralChief• over 1 year ago
Replying to @ultimape

@ultimape @haidut Makes sense. Just stopping iron supplementation alone can have quite a favorable effect on the microbiome.. Iron is quite the food for bacteria especially when it is in supplement form. Copper deficiency and gut infections are likely the main causes of anemias IMO.

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8/27/2024
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UltimApe@ultimape• over 1 year ago
Replying to @MineralChief

@MineralChief @haidut I think so too. My increase in zinc was to impact copper regulation. Worked a treat alongside some stuff to make sure my body was using vitamin A correctly. I can litterally see in the dark now haha. https://t.co/Typg4dcwZ4

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UltimApe@ultimape• over 1 year ago

@Hair_Artiste I'm using plant chemicals (diet) to promote my gut bacteria to convert vitamin A1 into vitamin A2 for me, if you are curious.https://t.co/btHSiZNhdC

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8/27/2024
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Mineral Chief@MineralChief• over 1 year ago
Replying to @ultimape

@ultimape @haidut oysters have a fair amount of mercury and cadmium... these heavy metals are quite dangerous.. some good chelated zinc cant be that bad? Do you eat red meat? Dark chocolate is also quite high in lead and cadmium even the best brands still contain a fair amount.

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8/27/2024
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UltimApe@ultimape• over 1 year ago
Replying to @MineralChief

@MineralChief @haidut I'm working on eating lead too. The high B6 in the garlic makes the selenium better able form complexes with the heavy metals & shifts enzymes. It lets me shit them out. My blood work was clean. https://t.co/fmLklvtKOs

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8/27/2024
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UltimApe@ultimape• over 1 year ago
Replying to @ultimape

@MineralChief @haidut I go for the ones with more lead cuz I think it's funny.

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8/27/2024
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UltimApe@ultimape• over 1 year ago
Replying to @ultimape

@MineralChief @haidut In nature, plants use bacteria to extract metal from the soil. if you look at how nature handles metals, you can completely side step fears of heavy metals.I got into more details on this on bluesky with respect to chocholate specifically https://t.co/JK0OcuNSkz

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8/27/2024
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UltimApe@ultimape• over 1 year ago
Replying to @ultimape

@MineralChief @haidut Eat more garlic https://t.co/2A3MVgKSKu

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UltimApe@ultimape• over 3 years ago

"If garlic is so effective at pulling lead out of chickens’ bodies, why not more directly exploit “garlic feeding” by eating it ourselves? Well, there had never been a study on the ability of garlic to help lead-exposed humans until…2012?" https://t.co/zLTr2nYjIe https://t.co/62jnJqPXt0

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8/27/2024
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Mineral Chief@MineralChief• over 1 year ago
Replying to @ultimape

@ultimape @haidut Why because of the sulfur? Most bloodwork is a scam. Sure you can predict metabolism and oxidation status with HTMA but how useful is it really when you just know what minerals to take and understand the feeling of when you take too much of something?

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8/27/2024
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UltimApe@ultimape• over 1 year ago
Replying to @MineralChief

@MineralChief @haidut What I figure out is how to optimize gut health to make it so I don't need as many minerals and use them to address oxidative stress factors instead.

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8/27/2024
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Mineral Chief@MineralChief• over 1 year ago
Replying to @ultimape

@ultimape @haidut What kind of gut microbiome modulators do you use?

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8/27/2024
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UltimApe@ultimape• over 1 year ago
Replying to @MineralChief

@MineralChief @haidut Kefir, Kombucha, Saurkraut, Natto, Kimchii and Various beers and herbal teas. I also did a radical FMT.https://t.co/RYSNGDCUmp

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UltimApe@ultimape• over 2 years ago

@no_identd @Valuable @_ali_taylor Chelating heavy metals out of my system is one of the things I have been trying to fix because I grew up in the wash water of a superfund site. The copper load probably messed me up. Now I got that dawg in me.https://t.co/vBPJAfOIVxhttps://t.co/WIpqAzfWLO https://t.co/vWc6MHzbqM

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8/27/2024
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Mineral Chief@MineralChief• over 1 year ago
Replying to @ultimape

@ultimape @haidut the problem with well water is corelated much higher with iron.. the iron load can be huge... and far more damaging than isolated copper. Some people are taking 50mg of copper a day and are fine.

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8/27/2024
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UltimApe@ultimape• over 1 year ago
Replying to @MineralChief

@MineralChief @haidut The lactoferrin in the kefir helps with that a lot. https://t.co/VtCjw3x686

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8/27/2024
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Mineral Chief@MineralChief• over 1 year ago
Replying to @ultimape

@ultimape @haidut copper is the more human way to activate our endogenous mechanism for this via ceruloplasmin and transferrin... lactoferrin is still pretty epic.. how much copper, manganese and iodine are you getting? They seem to work well with super oxide dismutase and and redox balancing.

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8/27/2024
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UltimApe@ultimape• over 1 year ago
Replying to @MineralChief

@MineralChief @haidut I stopped tracking my copper one I stopped having m.s.

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8/27/2024
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UltimApe@ultimape• over 1 year ago
Replying to @ultimape

@MineralChief @haidut The kefir also neutralizes the cancer causing chemical in blackstrap (acrylamide) so it's a nice combo to make sure the iron is going into the system here it is needed and not fueling pathogenic e. coli.

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8/27/2024
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Mineral Chief@MineralChief• over 1 year ago
Replying to @ultimape

@ultimape @haidut Iron an Omega 6 are highly correlated with the development of lipofuscin. I think vitamin A dysregulation along with this can be pretty terrible. Exposure to mold exacerbates the issue.

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8/27/2024
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UltimApe@ultimape• over 1 year ago
Replying to @MineralChief

@MineralChief @haidut Yep, my FMT was done on a hunch that I wasn't able to convert omega 6 to omega 3 properly and maybe explains weird fidings around omega 3/6/9 levels in schizophrenics despite dietary levels.We don't have human studies on that, only a couple in dogs.

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8/27/2024
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UltimApe@ultimape• over 1 year ago
Replying to @ultimape

@MineralChief @haidut Similarly, most of the work we have on minerals and gut health haven't been done in humans. I had to proxy it thru reading stuff about animal health findings and translating it to how humans seem to differ. https://t.co/DbYM0BbeqI

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8/27/2024
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UltimApe@ultimape• over 1 year ago
Replying to @ultimape

@MineralChief @haidut No one can ever tell me what I want to know. https://t.co/oD0gIRWbkU

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UltimApe@ultimape• almost 4 years ago

@jwmares I take my last pill soon. It's working well.What biomarkers would you expect to see improve if it's hitting omega-6 related inflammatory pathways?I ordered a second Viome to do a before-and-after.

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8/27/2024
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UltimApe@ultimape• over 1 year ago
Replying to @ultimape

@MineralChief @haidut But I can tell you for certain that seed oils stopped giving me the shits. haha.

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8/27/2024
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Mineral Chief@MineralChief• over 1 year ago
Replying to @ultimape

@ultimape @haidut lowering omega 6 intake lowers the competition for omega 3 binding. What bacterial species are responsible for converting omega 6 to 3 or is it actually ALA to EPA DHA that is being converted by good bacteria?

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8/27/2024
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UltimApe@ultimape• over 1 year ago
Replying to @MineralChief

@MineralChief @haidut No idea. lmao https://t.co/WxI0gOXIzm

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UltimApe@ultimape• over 1 year ago

@CoiningBits @Hair_Artiste @Grimhood @StillmanMD @DrJackKruse @TuckerGoodrich I reasoned thru this space and findings in gut bacteria's role in hibernaing animals to surivive, and emulated roughly ways they "get out of hibernation". The mechanism Grim talks about with omega 3s displacing omega 6 is part of this shift.

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8/27/2024
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UltimApe@ultimape• over 1 year ago
Replying to @ultimape

@MineralChief @haidut That's a good question tho. I am doing all of this on a shoestring budget of like $100 a month haha. I would have loved to have proper metabolite assays.

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8/27/2024
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UltimApe@ultimape• over 1 year ago
Replying to @ultimape

@MineralChief @haidut My best alternate guess is its more that having better SCFA balance is buttressing against the omega 6's inflammatory effects. Whatever it is I no longer seem to have any problems that people commonly ascribe to seed oil consumption.

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8/27/2024
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Mineral Chief@MineralChief• over 1 year ago
Replying to @ultimape

@ultimape @haidut Yes the butyrate and propionate and stearic acid appear to be the key.. I believe our microbiome can also make the C15 saturated fat that is all the rage right now.

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8/27/2024
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UltimApe@ultimape• over 1 year ago
Replying to @MineralChief

@MineralChief @haidut Similarly, I believe many people following peats advice are supplementing coconut oil to compensate for poor fatty acid production. I ate so much butter (high in C15) before to just keep my gut from having trouble.

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8/27/2024
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UltimApe@ultimape• over 1 year ago
Replying to @ultimape

@MineralChief @haidut Pentadecanoic acid seems to act like butyrate. They even mimic each other in HDAC inhibitor ability https://t.co/kMmWDld8Hp

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8/27/2024
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UltimApe@ultimape• over 1 year ago
Replying to @haidut

@haidut many antidepressants disrupt the gut microbiome and literally can dysrupt akkermancia muciniphila, a known gut commensal that can make choline and niacin (nicotinic acid that is formed by niacinamide). https://t.co/hKjfZyTA8qDrug induced deficit due to gut dysbiosis. https://t.co/aigXF0nt2N

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8/27/2024
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UltimApe@ultimape• over 1 year ago
Replying to @ultimape

@haidut Interestingly, Akkermancia Muciniphila can actually improve depressive traits! This could explain paradoxical response to SSRIs for some people. https://t.co/RPMfpddCPg

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8/27/2024
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UltimApe@ultimape• over 1 year ago
Replying to @ultimape

@haidut I had some weird ideas https://t.co/00SuTF7rB7

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UltimApe@ultimape• over 2 years ago

Thanks to a weird joke on bluesky, I have concluded that POIS can be cured by gut bacteria.Can you imagine it? Local autistic man solves POIS by wondering how eating god's shit could make us immune to god's cum.https://t.co/PFWFZWsRS3

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8/27/2024
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UltimApe@ultimape• over 1 year ago
Replying to @ultimape

@haidut *ALL* my allergies went away when I did my FMT https://t.co/u7G8p79Uve

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UltimApe@ultimape• over 1 year ago

Oh hey, look at that, the "washed microbiota" thing that was being trialed to treat autism ( https://t.co/BpmVHCKmsn ) also seems to work for POIS.https://t.co/ooJKRDWalu Imagine that.

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8/27/2024