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🧵 Thread (98 tweets)

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UltimApe@ultimapeabout 3 years ago

I'm Post Rat. In fact I'm into squirrels now. I figured out how to make them (and chipmunks) not afraid of me."One study used these scent markings to help overcome neophobia with lures by mixing grease, dust, hair and scent marks within urinary pillars."https://t.co/xzeIEgS2yJ https://t.co/GHoX8rSYYm

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8/22/2022
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UltimApe@ultimapeabout 3 years ago
Replying to @ultimape

I think a lot about rodent pee and it's impact on postrat-esque fear behavior.https://t.co/yk266EeLuw

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UltimApe@ultimapeabout 5 years ago

I've had to halt my experiments with the minibears because an actual bear has been tipping over the bear proof dumpster on the other side of the building.I was so hoping to find out if they pee'd on me.https://t.co/soPu2rp9hV

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8/22/2022
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UltimApe@ultimapeabout 3 years ago
Replying to @ultimape

This also works on cats. Cats seem to enjoy marking up everything that they feel safe with. You can manipulate this by wearing really tall socks and then then rubbing it everywhere you want them to travel.

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8/22/2022
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UltimApe@ultimapeabout 3 years ago
Replying to @ultimape

I am not trying to make a cat lay down with a rodent, I don't know what you're talking about.https://t.co/DDqHplPB1t

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UltimApe@ultimapealmost 6 years ago

I am diogenes. I want to speak cat. I want to stink like a bear. I want to communicate with mice, and maybe one day ants.Spreading cat pheromones on a lamb so that the lion might lay with it. Isaiah 11:6 is not a metaphor?

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8/22/2022
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UltimApe@ultimapeabout 3 years ago
Replying to @ultimape

What happens if you give a rat some cat microbes and vice versa. Do they shift their pheromones' to the point where they think they are brothers?https://t.co/j7Ef3OWWK8

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UltimApe@ultimapeabout 3 years ago

Ah yes, magic. What we call rituals we don't understand."Several Native American tribes have longstanding beliefs that spitting in a dog’s food is how to get it to bond with you." https://t.co/N3aaihzkQR

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8/22/2022
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UltimApe@ultimapeabout 3 years ago
Replying to @ultimape

Wait till you find out that lobsters and ants are the same lineage and I've figured out how to manipulate their production of hydrocarbons and shift the way they form hierarchies.https://t.co/sphPcVZYiX

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UltimApe@ultimapeover 3 years ago

Did you know lobsters are related to grasshoppers thru serotonin pathways?Lobster hierarchies aren't some preordained social construct, they're what happens when insects try to eat each other.https://t.co/QXc9KVzZVO

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8/22/2022
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UltimApe@ultimapeabout 3 years ago
Replying to @ultimape

I have been told that lobsters pee from their face. I have not been able to confirm this via YouTube videos.https://t.co/Wrw1wRQY6F

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8/22/2022
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UltimApe@ultimapeabout 3 years ago
Replying to @ultimape

*holds up gerbil with modified gut bacteria that mpacts serotonin and androgen production under stress*Is this your hierarchal model of social dominance?https://t.co/FaPYVuoGP8

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8/22/2022
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UltimApe@ultimapeabout 3 years ago
Replying to @ultimape

I shall be come the king of order rodentia.https://t.co/kUFoWtnNq7

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UltimApe@ultimapeover 4 years ago

The term "to cow someone" is literally about controlling them via fear. I do not use this terminology by mistake.A lot of old tweed materials smelled of pee when wet b/c use of ammonia as a fabric manipulation aid before invention of air conditioning.https://t.co/7yVjkIzluN

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8/22/2022
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UltimApe@ultimapeabout 3 years ago
Replying to @ultimape

Magic tricks are what happens when you figure stuff out and pretend you are a Magi.https://t.co/HTLSNuCP5D

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UltimApe@ultimapeover 3 years ago

I am really good at thinking like a mouse, because a mouse is just a funny looking rat, and rats are basically mammalian ants.No one looks for urine marking behavior it seems. We have a collective gell-mann amnesia around the impact of scent on behavior.https://t.co/5U9p5ktPtM

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8/22/2022
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UltimApe@ultimapeover 2 years ago
Replying to @ultimape

Load bearing rat studies.https://t.co/i3cCQrwIcs

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UltimApe@ultimapeover 2 years ago

Diving down the rabbit hole of literal load bearing bad science studies. https://t.co/N8FMJw7iRZ

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6/13/2023
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UltimApe@ultimapeover 2 years ago
Replying to @ultimape

Pulling a rabbit out of a hat and calling it a pooka, like some kind of twisted Diogenes.https://t.co/mNa6Qagw2p

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UltimApe@ultimapealmost 3 years ago

Chase rabbits down holes until you can pull one back out like some kind of magician.https://t.co/uamFCyriOT

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6/13/2023
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UltimApe@ultimapeover 2 years ago
Replying to @ultimape

Diving into some holes, BRB.https://t.co/7f7l9Pdug7

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6/13/2023
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UltimApe@ultimapeover 2 years ago
Replying to @ultimape

MFW having a big think about scientific hoaxes.https://t.co/i1IgLWnXUV https://t.co/BQFfxcYtxX

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UltimApe@ultimapeabout 4 years ago

That's not just a bad study; that's a load bearing bad study. Entire industries are predicated on the delusion that this study is true. Why do you hate people being employed?

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6/13/2023
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UltimApe@ultimapeover 2 years ago
Replying to @ultimape

oh. Oooooh. Was that "maternal impression" theory the inspiration for some of the most f*cked southpark episodes? https://t.co/qC4wwKAYzH

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6/13/2023
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UltimApe@ultimapeover 2 years ago
Replying to @ultimape

This is quite a rabbit hole indeed."This book laid out the theory of “maternal impression,” the idea that a mother’s thoughts, obsessions, and fancies could imprint themselves on the form of the unborn child."https://t.co/0lAYs20oks

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6/13/2023
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UltimApe@ultimapeover 2 years ago
Replying to @ultimape

It looks like Ian Stevenson has been writing about it for a while. I found a review paper from 1992 that is trying to claim this is paranormal activity.https://t.co/iCTMpk0HQW

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6/13/2023
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UltimApe@ultimapeover 2 years ago
Replying to @ultimape

And they have a follow up from 2017 published in a book on parapsychology https://t.co/3N9GyOdkGR

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6/13/2023
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UltimApe@ultimapeover 2 years ago
Replying to @ultimape

This belief is a Stirnerian spook. "I argue that maternal impressions worked to maintain anxiety for women, and particular white women, to ensure they felt responsible if anything was “wrong” with their child." https://t.co/H3inQV2we1

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6/13/2023
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UltimApe@ultimapeover 2 years ago
Replying to @ultimape

Could, in rare cases, the mental imagery and beliefs of the mother impact the body plan expression of her child? Or for that matter, could an old injury from the father cause the sperm to communicate some kind of birth defect due to impaired wound healing?

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6/13/2023
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UltimApe@ultimapeover 2 years ago
Replying to @ultimape

If aging sperm can cause birth defects and risk of neurological disease by way of acting on the immune system, could there be more information being imparted thru that RNA or some other mechanism?

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6/13/2023
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UltimApe@ultimapeover 2 years ago
Replying to @ultimape

"It seemed that sperm at different points along the reproductive tract had the same genetics, but not the same epigenetics. Was this difference big enough to matter?" https://t.co/dDgTNKMR3J

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6/13/2023
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UltimApe@ultimapeover 2 years ago
Replying to @ultimape

That could be an alternate explanation for the man who's old damaged hand could ended manifesting in weird growth in his daughter. And be completely adjacent from the Maternal impression theory, without any paranormal activity.

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6/13/2023
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UltimApe@ultimapeover 2 years ago
Replying to @ultimape

That doesn't explain every case presented here https://t.co/YQD11vy0ddBut it is a neat idea and at could explains at least one of the ones cited in that 1992 review. https://t.co/cOQ1QE45hA

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6/13/2023
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UltimApe@ultimapeover 2 years ago
Replying to @ultimape

of course the obvious explanation is that these birth marks are falling for a Confirmation Bias, and the author is trying to find examples of paranormal activity and ignores all the birth defects unreported, or finding just-so explanations.

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6/14/2023
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UltimApe@ultimapeover 2 years ago
Replying to @ultimape

But I'm going to run with this wound-immune-bodyplan memory effect because even if it is 100% not related to the prescribed phenomena. I might learn something.I also have a hunch.

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6/14/2023
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UltimApe@ultimapeover 2 years ago
Replying to @ultimape

Grant the Premise, y'know? Might find things others have overlooked in their desire to not know the truth. And the truth is out there ;) https://t.co/dITSumvyk7

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6/14/2023
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UltimApe@ultimapeover 2 years ago
Replying to @ultimape

Ok, what do I know about body plan memory?

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6/14/2023
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UltimApe@ultimapeover 2 years ago
Replying to @ultimape

Oh yeah. It's those Cyborg Frogs. I have the documents! https://t.co/bqafsrgd16

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UltimApe@ultimapeover 5 years ago

Lots of people keep sharing articles about those xenobots with me.Not many people realize that this stuff has been on my radar for a while.In other news. UVM's evolutionary robotics lab is really fun if you are interested in literal artificial life. https://t.co/Bs3GUtR7zv

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6/14/2023
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UltimApe@ultimapeover 2 years ago
Replying to @ultimape

What do you mean embodied memory?https://t.co/V2quQDkhfT

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UltimApe@ultimapeover 4 years ago

@The_Lagrangian @insurrealist "Researchers discover flat worms retain memories even after decapitation"https://t.co/nkhPKa9X6rhttps://t.co/Qzk81HIiRN

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6/14/2023
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UltimApe@ultimapeover 2 years ago
Replying to @ultimape

Don't mind me, just exploring how a massive injury and mental stress might impact sperm and effect the "The electrical blueprints that orchestrate life"https://t.co/0LQjuLftx6

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UltimApe@ultimapeabout 3 years ago

@seconds_0 @noor_siddiqui_ @OrchidInc @seedhealth Nah. I don't need to. I already figured this out enough that I predicted that was what they were working on back in 2014 when I wanted to get a phd in evolutionary robotics.https://t.co/qakHrLJJDl

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6/14/2023
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UltimApe@ultimapeover 2 years ago
Replying to @ultimape

Surely you don't mean that a father's sperm might have some imprint of cellular memory in it somehow?"Cell Intelligence in Physiological and Morphological Spaces" https://t.co/5UzeNngx2G

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6/14/2023
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UltimApe@ultimapeover 2 years ago
Replying to @ultimape

I mean, of course I know about how to act on the body to interact with regeneration primitives. it's not like all my scars have gone away and I'm trying to figure out how regenerate ovaries or anything...https://t.co/ocBy7nOlb9

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6/14/2023
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UltimApe@ultimapeover 2 years ago
Replying to @ultimape

Could an extreme injury or stressful event cause "cellular memory" to not be erased during Spermatogenesis/oogenesis, (or preserved via RNA) and instead passed on to the child?https://t.co/X8yTLFeUpd https://t.co/ipz1gB71Uc

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6/14/2023
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UltimApe@ultimapeover 2 years ago
Replying to @ultimape

This is all absolutely speculative of course. But something like it would be a direct explanation for how the immune system would be acting to redirect and modify cellular scaffolding without any paranormal activity.

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6/14/2023
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UltimApe@ultimapeover 2 years ago
Replying to @ultimape

Oh neat, some scientist found out that there are nuggets of epigenetic inheritance passed on via a RNA based mechanism (in worms).https://t.co/Qx6BDrgGRC

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6/14/2023
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UltimApe@ultimapeover 2 years ago
Replying to @ultimape

So, we found a kind of biological engram in C. Elegans? LOLhttps://t.co/mRwUwjP4oihttps://t.co/Y7La4TZNTZ

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UltimApe@ultimapealmost 3 years ago

Therapist: Engram's aren't really and can't hurt you.Karl Lashley's engrams as a unit of cultural knowledge: https://t.co/3Mk5jPRR9Q

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6/14/2023
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UltimApe@ultimapeover 2 years ago
Replying to @ultimape

Now, that's' a far cry from being able to store and propagate some kind of ancestral memory like some kind of thetan based mind meld.

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6/14/2023
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UltimApe@ultimapeover 2 years ago
Replying to @ultimape

But fascinating to think that it could at least impact some kind of immune memory somehow and impact a birth defect thru a glitch during limb remodeling in rare cases where the cellular memory isn't wiped cleanly.

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6/14/2023
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UltimApe@ultimapeover 2 years ago
Replying to @ultimape

I'm telling you, this thing is a spook ;)https://t.co/SkHnysMpNy

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UltimApe@ultimapeover 5 years ago

How many bits is an engram. Does it need to exist in a memristor? If Engrams create behavior, are they a precursor to the concept of a meme?https://t.co/fMaUz7Ng6Ghttps://t.co/tn51bXwKdcHaunted by kind ghosts.https://t.co/0Wy8mF2oYU https://t.co/UtzA3Cneks

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6/14/2023
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UltimApe@ultimapeover 2 years ago
Replying to @ultimape

"Although positional memory is well documented at a phenomenological level, the underlying cellular and molecular bases are just beginning to be decoded." https://t.co/VVmoeGe5l9Salamander? Adult Axolotl.https://t.co/t5Fz1szCkL

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UltimApe@ultimapeabout 4 years ago

@balajis @The_Lagrangian @almostlikethat **"Although the activity of the immune system in the aging axolotl has not been studied"**Do you ever find yourself knowing a significant amount of information in the exact space where an animal model of aging and limb regeneration end up having a lack?https://t.co/1z0gf4PJEu

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6/14/2023
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UltimApe@ultimapeabout 2 years ago
Replying to @ultimape

How strange. Epigenetic shifts due to diet?> "He stated that their deterioration included "germ plasm injury" causing them to pass acquired anatomical defects to their offspring.[4] However, the idea of acquired characteristics has been discredited.[5]"

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6/17/2023
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UltimApe@ultimapeabout 2 years ago
Replying to @ultimape

From wikipedia for "Francis M. Pottenger Jr.", which I can't link to due to the trailing period being interpreted as part of the tweet and not a URL.

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6/17/2023
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UltimApe@ultimapeabout 2 years ago
Replying to @ultimape

Do you ever wonder if we (humans) can change our inheritance patterns?No one talks about how vaginal crypts could potentially storing and preserving semen, or how there is no reason why we can't pause gestation like deer.https://t.co/Ssrp6LuN7Ohttps://t.co/cnAeU1L4Si https://t.co/bn58Khnxrm

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UltimApe@ultimapealmost 7 years ago

Oh wait. "genetic analysis of the gynandromorphs also discovered that one bee had 4 parents (three fathers and a mother) [...] This is the first report of a phenomena of a bee with two fathers and no mother in hymenoptera"https://t.co/MR9JTLQsfg

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7/23/2023
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UltimApe@ultimapeabout 2 years ago
Replying to @ultimape

How could a gene mutation lead to multiple generations of maned lionesses despite the gene itself not being inherited? Because it tweaks immune system regulating chemicals tied to cholesterol (estrogen/testosterone) via gut bacteria related epigenetics.https://t.co/SGIRMUvFXc

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UltimApe@ultimapeabout 3 years ago

@__________1890 @Outsideness @realMaxCastle @nihilaxis Transgenerational stuff can be got thru gut bacteria's impact on epigenetic signaling. Shows up in maned lioness phenomena, so we should be able to test gut microbes there to see it in action.

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7/23/2023
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UltimApe@ultimapeabout 2 years ago
Replying to @ultimape

Throw in weird phenomena around male mitochondrial DNA sometimes being inherited and shit gets weird. You can spot the assumption that it is entirely matrilineal in lion research.https://t.co/D99GUfTSO4

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7/23/2023
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UltimApe@ultimapeabout 2 years ago
Replying to @ultimape

Muh lions. Can't find what you don't look for. You don't look for it if you assume it is impossible.https://t.co/BdQq9C10hJhttps://t.co/eeg7C0hxL7 https://t.co/iNVl3mWLe3

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UltimApe@ultimapeover 6 years ago

They found the maned lioness epigentic effect in mice, so thats a start.High testosterone in mothers passed on to daughters... (something that seems to play an epigenetic role in pcos, autism, and schziophrenia risks during gestation) https://t.co/7ekfD6aNnu

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7/23/2023
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UltimApe@ultimapeabout 2 years ago
Replying to @ultimape

"While the males live for only a few hours after their mating flight, the queen will store their sperm and can use it over the course of the next decade to produce new offspring."https://t.co/9GeHuaRWC7https://t.co/Fa47DEwrWN

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UltimApe@ultimapeover 6 years ago

Why aren't you studying ants?https://t.co/EOWRE54rsV

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7/23/2023
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UltimApe@ultimapeabout 2 years ago
Replying to @ultimape

What conditions makes this happen?"The capacity for sperm storage within the female reproductive tract occurs widely across all groups of vertebrate species and is exceptionally well developed in some reptiles" https://t.co/FH2WaQdbGg

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7/23/2023
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UltimApe@ultimapeabout 2 years ago
Replying to @ultimape

If maned lionesses are a colony level emergent response to resource scarcity as a way to protect a pride from roving bands of weak males, does that mean its something tied to metabolic health vis-a-vis gut metabolites impacting gene expression?

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7/23/2023
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UltimApe@ultimapeabout 2 years ago
Replying to @ultimape

If 'pausing' a pregnancy is also something that happens related to metabolic health -> shifting the gestation to a more opportune time. Could this also be related to gut bacteria impacting epigenetics?

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7/23/2023
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UltimApe@ultimapeabout 2 years ago
Replying to @ultimape

"Although scientists have known since the 1850s that some animals have this ability, it is only now becoming clear how it could teach us valuable lessons about human pregnancy, stem cells, and cancer." [OCT 2019]https://t.co/nLezm7yo4uhttps://t.co/S0weUseo99

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UltimApe@ultimapeover 6 years ago

Dog butt theory of autism crossed with the maned lioness, using it to prevent heart disease because of female bear penis.If this works in the next few months, I'm moving on to curing cancer.

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7/23/2023
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UltimApe@ultimapeabout 2 years ago
Replying to @ultimape

What happens to insects during famine and metabolic drought? Their gut bacteria start dumping serotonin in and their body plan changes.https://t.co/h1qalf98R5

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UltimApe@ultimapeover 3 years ago

"Therefore, it appears that the evolutionary changes in the endosymbiotic bacteria have profound implications on host biology." [2020]https://t.co/iOu7G7KF27 https://t.co/g7NhxEsz1P

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7/23/2023
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UltimApe@ultimapeabout 2 years ago
Replying to @ultimape

Called it."Hardship experienced by mothers during their own childhood or during pregnancy is reflected in the composition of their 2-year-old children's gut microbiomes" [JUL 21 2023]https://t.co/603RzV1WCHhttps://t.co/QPiqYwmzbg

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UltimApe@ultimapeover 4 years ago

Semi-regular reminder that you can also inherit gut bacteria. https://t.co/TVzf0MPz7G https://t.co/TJRnRmtXtY

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7/23/2023
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UltimApe@ultimapeabout 2 years ago
Replying to @ultimape

"Moreover, they raise the possibility that mothers can confer immune protection to their offspring even to pathogens that they haven't themselves encountered in the past." https://t.co/GSyxxOmrII

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7/23/2023
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UltimApe@ultimapeabout 2 years ago
Replying to @ultimape

"Studies have even found that though your mother gave you many microbes during birth and through breastfeeding, most children have gut microbiomes just as similar to their father's as their mother's."https://t.co/cTx0uIL6J9

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7/23/2023
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UltimApe@ultimapeabout 2 years ago
Replying to @ultimape

"Some research on mice has shown that after several generations of passing on fewer good microbes, the losses are compounded, which may affect health."https://t.co/4bR8cq01SB

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7/23/2023
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UltimApe@ultimapeabout 2 years ago
Replying to @ultimape

"All three studies, which haven’t yet been published in peer-reviewed journals, point to a possible role that a buildup of “bad” bacteria in the gut could play in cognitive health." [JUL 19 2023]https://t.co/z6zyGjWOFi

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7/23/2023
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UltimApe@ultimapeabout 2 years ago
Replying to @ultimape

Every article out there seems to cite how sperm can live up to 5 days in the vaginal tract. But here's a paper from 1972 talking about 9-12 days and associating it with estrus cycle, even surviving menstruation. https://t.co/22WXkD284M

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7/23/2023
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UltimApe@ultimapeabout 2 years ago
Replying to @ultimape

This 1997 article seems to be the source of the 5 days citation for sperm viability. Motherfucks never wonder if these mathematical models might be wrong, or biased toward some assumptions that may not hold true for everyone?https://t.co/Bz7R6eDnhY https://t.co/9zVLXCaLuW

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7/23/2023
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UltimApe@ultimapeabout 2 years ago
Replying to @ultimape

Did you know Myo-inositol & n-acetylaspartate is related to gut-brain axis?"The genera Bacteroides and Clostridium predicted higher concentrations of a brain chemical called myo-inositol, while Butyricimonas predicted one called n-acetylaspartate (NAA)."https://t.co/OowN3MuWs2

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7/23/2023
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UltimApe@ultimapeabout 2 years ago
Replying to @ultimape

Those are both impacted by stress and are why cortisol is seen as a way for the gut to communicate with the brain.

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7/23/2023
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UltimApe@ultimapeabout 2 years ago
Replying to @ultimape

"treating fertile women with myo-inositol (MI) vaginal suppositories ameliorated their partners' sperm motility and also positively affected their conceiving capacity, without changes in cervical mucus structural and biochemical characteristics."https://t.co/qiL3U7kD3J

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7/23/2023
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UltimApe@ultimapeabout 2 years ago
Replying to @ultimape

"There were significant relationships between vitamin B6 and N-acetylaspartate (NAA), choline, and creatine, as well as between vitamin B12 and creatine (ps < 0.05), whereas NAA in the PCC increased, albeit not significantly (p > 0.05)." https://t.co/zudGoEHhPC

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7/23/2023
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UltimApe@ultimapeabout 2 years ago
Replying to @ultimape

A Atxn2 gene knock-out mouse shows that impairments in N-acetylaspartate relate to it's mechanism of action. https://t.co/IrNiziRVz1

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7/23/2023
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UltimApe@ultimapeabout 2 years ago
Replying to @ultimape

Atxn2 ablated mice causes failed embryogenesis and failed gestation.https://t.co/YUVNNJDD7z

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7/23/2023
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UltimApe@ultimapeabout 2 years ago
Replying to @ultimape

That related Nat8l gene leads to poor neurogenesis and death when the mouse infant has no fat in its diet, but fixed via N-acetylaspartate supplementation https://t.co/yKQXP06DhY

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7/23/2023
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UltimApe@ultimapeabout 2 years ago
Replying to @ultimape

Do you ever wonder if cortisol production via metabolite dysfunction from impaired gut bacteria are what cause PCOS to have high rates of infertility, miscarriage, and cause a risk of autism?https://t.co/H9zRZisJKi https://t.co/3xlEeN9NqL

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UltimApe@ultimapeabout 2 years ago

Did you know Myo-inositol & n-acetylaspartate is related to gut-brain axis?"The genera Bacteroides and Clostridium predicted higher concentrations of a brain chemical called myo-inositol, while Butyricimonas predicted one called n-acetylaspartate (NAA)."https://t.co/OowN3MuWs2

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7/23/2023
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UltimApe@ultimapeabout 2 years ago
Replying to @ultimape

And by extension, speculate that dietary factors may play a role in sperm health and function, thus leading to higher rates of fertility among healthy women? Then go on to cure PCOS in your GF?https://t.co/6mB4m5OIyb

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UltimApe@ultimapeabout 2 years ago

@GoodTexture @BioavailableNd The trick to figurin this out is that there are populations of people who all have PCOS genetics but don't suffer from PCOS related infertiltiy or menstral cycle problems. They all eat a heathy diet full of fresh food (low preservatives) and organ meats as well as fermented food.

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7/23/2023
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UltimApe@ultimapeabout 2 years ago
Replying to @ultimape

gut brain vag axis lmao.https://t.co/DJSzLWGkkF

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UltimApe@ultimapeover 3 years ago

Modeling PCOS as a disruption in structural and function in the brain.https://t.co/QzT2gJzhQa

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UltimApe@ultimapeabout 2 years ago
Replying to @ultimape

Anyway, fix your gut so B vitamins don't impair metabolic health and cause you fertility problems. https://t.co/EuDVC2sTVr

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UltimApe@ultimapeover 2 years ago

You can make some pretty wild guesses on the role of gut bacteria by looking at how regulating homocysteine levels works in hibernating animals despite no B vitamin intake.https://t.co/FIAg0esndV https://t.co/uDQAWoKJPR

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UltimApe@ultimapeabout 2 years ago
Replying to @ultimape

Eat some garlic.https://t.co/WyyXBBq6y1

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UltimApe@ultimapeover 2 years ago

@Grimhood Ah! So Selenium (Garlic) and Molybdenum (Stinging Nettle) would let me use B2 better. That may explain why I've not had any problems with B6 from garlic -> it might be all being converted more effectively in the liver?

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UltimApe@ultimapeabout 2 years ago
Replying to @ultimape

Fix your NADs.https://t.co/4nVZr5eK3U

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UltimApe@ultimapeabout 3 years ago

I am now learning about Kynurenine. I wanna know why B6 makes me get diarrhea and not NAD+.https://t.co/TM6lyahubWhttps://t.co/IPTRwHc0C7 https://t.co/yVc1byj6Oe

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UltimApe@ultimapeabout 2 years ago
Replying to @ultimape

That was a joke, i'm not SIRTn that NADs matter as much here.https://t.co/UrCtIFXhSl

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UltimApe@ultimapeabout 3 years ago

Looks like some of the NAD+ papers have been flagged for cloned images and other fraud adjacent science fuckery.Maybe I shouldn't care so much about NAD and focus on Sirtins like I've been doing.https://t.co/NAR7QsjiXb https://t.co/eLnfd5jXnp

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UltimApe@ultimapeabout 2 years ago
Replying to @ultimape

"Hence, the study of the role of SIRT1 in the pathogenesis of PCOS and related complications will contribute to a more thorough understanding of the pathogenesis of PCOS and supply a basis for the treatment of patients" [aug 2022] https://t.co/etb3M9lwZAhttps://t.co/vgFBnqh4sB

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UltimApe@ultimapealmost 5 years ago

Ya'll ever look up SIRT-1 and realize you've been exploring those pathways indirectly while trying to fix age-related diseases tied intimately to the gut and immune function?No? Just me? Well then.https://t.co/UfzoVUBahS

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UltimApe@ultimapeabout 2 years ago
Replying to @ultimape

Tired: Post RatsWired: Fat Tailed Lemurshttps://t.co/AYjtwPFrNehttps://t.co/QRks5fRHSF https://t.co/GjnRW1PLPP

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UltimApe@ultimapealmost 4 years ago

@MMMalign weird ideas about over looked circadian rhythm impacts of lemur gut bacteria, that we assume is endogenous because we aren't looking for gene-gut interplay.https://t.co/PS9spnBvcN

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UltimApe@ultimapeabout 2 years ago
Replying to @ultimape

"Expectant lemur dads see hormonal changes in response to pregnant mates, poop shows" https://t.co/GgOJd7PCL2

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7/23/2023
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UltimApe@ultimapeabout 2 years ago
Replying to @ultimape

"Males, when they're expecting, even when they're not carrying the infant, are responding to the developing fetus, [...] I was shocked by how much of a change there is in estradiol when their partner is pregnant."I wonder how :3

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7/23/2023
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UltimApe@ultimapeabout 2 years ago
Replying to @ultimape

Why would a captive lemur get chonk? Are we killing their gut?"The first aim of our study was to examine possible ecological explanations for these species’ differences in susceptibility to captive weight gain across 13 lemur species." https://t.co/zpRF8pTetg

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7/23/2023
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UltimApe@ultimapeabout 2 years ago
Replying to @ultimape

"In zoos and animal sanctuaries (and the Duke Lemur Center), animals that would normally hibernate in winter often don’t. If they are warm and have adequate food, the stimulus for hibernation doesn’t appear." https://t.co/PPYVL51GHL

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7/23/2023
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UltimApe@ultimapeabout 2 years ago
Replying to @ultimape

"Researchers at the Duke Lemur Center studying the fat-tailed dwarf lemur in order to determine if their unique adaptations can help solve human biological problems."https://t.co/J3uWIDmooIhttps://t.co/6UIsIwkBma

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UltimApe@ultimapeabout 6 years ago

Why aren't you reading papers coming out of duke?https://t.co/VGwbgmT85i

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UltimApe@ultimapeabout 2 years ago
Replying to @ultimape

"Dausmann thinks the primates essentially return to a reptilian form of temperature regulation, relinquishing control of their body's thermostat to the environment and sparing themselves the energetic cost of waking up periodically during hibernation." https://t.co/C4He5xX8IR

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7/23/2023
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UltimApe@ultimapeabout 2 years ago
Replying to @ultimape

"During this time, the animal's metabolic activity decreases to about 2 percent of what it would be if it were active, and its body temperature drops to match the ambient temperature, which can drop to as low as 41 degrees Fahrenheit" https://t.co/A0bIMjvdmk

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7/23/2023
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UltimApe@ultimapeabout 2 years ago
Replying to @ultimape

"The tiny primate has gone into hibernation in captivity for the first time, and it could help humans get to Mars. […] we can learn a lot from the lemurs - including gaining better insight into metabolic disorders found in humans" https://t.co/mpuqsNxTry https://t.co/VC2X97FiIH

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UltimApe@ultimapeabout 2 years ago

If you do this, over time it just knits the networks together and they become a super-lemurian cluster. Welcome to the big-quartz vibemine. It's like a hivemind but worse.Become a spore today. You're already infected if you're reading this. https://t.co/QmqUyOUNBy

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UltimApe@ultimapeabout 2 years ago
Replying to @ultimape

Everybody thinks Fat Tailed Lemurs are the only primates that hibernate.Cute story bro, but you be wrong."Here, we report for the first time the observation that eastern dwarf lemurs also hibernate, though in self-made underground hibernacula." [2013]https://t.co/6c3YvxxWUj

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7/23/2023
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UltimApe@ultimapeabout 2 years ago
Replying to @ultimape

Sloths > Lemurs > Quokkashttps://t.co/dwKi8Z9tvy

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UltimApe@ultimapeabout 2 years ago

@drethelin They could probably rip up trees from the ground if their muscles are as strong as our current round of sloths. and would match native Americana stories of ice giants.I wanna pet one. I bet they are hek'n chonkers.https://t.co/ytxPX5OJNA

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UltimApe@ultimapeabout 2 years ago
Replying to @ultimape

Anyway, I went down a rabbit hole trying to look up if anyone was studying hibernating lemur cum and got distracted by cute things and hibernation.

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7/23/2023
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UltimApe@ultimapeabout 2 years ago
Replying to @ultimape

The truth is out there, and its weird.Not only is it weirder than we believe, it's weirder than we can believe.I want to believe.👽*cue xfiles theme in my head*https://t.co/ZUxO3nKxGF

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UltimApe@ultimapealmost 3 years ago

Thinking a lot right now about how DNA repair mechanisms and epigenetics / immune function all impacts semen quality. TL;DR: what if trauma is actually stored in the balls?

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UltimApe@ultimapeabout 2 years ago
Replying to @ultimape

Have you considered timing your masturbation to your circadian rhythm cycle so the hormones you release impacts your gut and drive vitality?https://t.co/QRks5fRHSF

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UltimApe@ultimapealmost 4 years ago

@MMMalign weird ideas about over looked circadian rhythm impacts of lemur gut bacteria, that we assume is endogenous because we aren't looking for gene-gut interplay.https://t.co/PS9spnBvcN

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8/16/2023
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UltimApe@ultimapeabout 1 year ago
Replying to @ultimape

Do you think Wild Lemur Cum is different from those held in captivity?https://t.co/itTmUm4EUD

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UltimApe@ultimapeabout 1 year ago
Replying to @ultimape

Do you believe in magic?in a young lemur's heart?Do you ever really wonder aboutWhat in the gut that makes your dog fart?https://t.co/dU5okp2sCX

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UltimApe@ultimapeover 4 years ago

@sly_clank @Oo_O_o00o_O_oO @0xa59a2d @Cernovich @zooko For my next magic trick, I'm going to be eating dog shit to show that mTOR related muscle gain in dogs is partly driven by gut bacteria.I even found a parasite free source of canine feces. Working toward a stable environment to do a proper test.https://t.co/uM9gPovp2z

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UltimApe@ultimapeabout 1 year ago
Replying to @ultimape

Rats aren't real and can't hurt you.https://t.co/svN50ncTJS

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UltimApe@ultimapeover 1 year ago

@SHL0MS Normal *lab rathttps://t.co/wLF5ZNKHLK

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UltimApe@ultimapeabout 1 year ago
Replying to @ultimape

How to solve a maze in an enclosed space:1) get really nervous2) explosive farting diarrhea3) run away from anything that smells bad.https://t.co/ruEMgiHr7j

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UltimApe@ultimapeover 3 years ago

Officially ignoring all conclusions derived from mice maze studies. https://t.co/Ji7G6kMYidhttps://t.co/oUfQokBB9B https://t.co/MmeapoeiL9

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UltimApe@ultimape12 months ago
Replying to @ultimape

Guaranteed to solve the maze, provided you have enough fart power.https://t.co/7T4SNP1BNI

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UltimApe@ultimapeover 4 years ago

"Shannon’s wry humor surfaces at the end of the Theseus film. He looks directly into the camera and notes that the method the mouse uses is mathematically guaranteed to “solve any possible maze.” And then, playfully, he traps the mouse in a single square."https://t.co/B4Akxgzq82 https://t.co/O6C1m9wo48

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UltimApe@ultimape6 months ago
Replying to @ultimape

Speaking of fart power.https://t.co/lTSjMu9Ob8

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UltimApe@ultimape6 months ago

> "Their findings, published in Biology Letters, suggest that these small primates can reverse cellular aging, offering potential insights for age-related disease research." https://t.co/IgAXfaBMRGhey! that's my area of focus!https://t.co/mnViryeHNh

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UltimApe@ultimape6 months ago
Replying to @ultimape

Have you considered improving your NADs?https://t.co/9dUcUdQCX6

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UltimApe@ultimape9 months ago

@MicroBerto @DoctorTro Hugely overlooked factor. I also doubled my grip strength with the FMT. So I was right on the money.All the effects of NAD+ without needing to supplement it!https://t.co/fDJr2dQZwL

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UltimApe@ultimape6 months ago
Replying to @ultimape

Throw em over your shoulder even?https://t.co/izZGxgUZAh

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UltimApe@ultimapeabout 5 years ago

@TechoTechy Did you know that pre-hibernation, squirrels become feminized and less agressive toward males and eventually form giant cuddle balls to survive the winter? They literally go thru puberty again in the spring to regrow their balls. Its wild.

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UltimApe@ultimape6 months ago
Replying to @ultimape

What happens to minerals that would be used for fertility, but suddenly become useless during hibernation?https://t.co/vDSmTBXFMJ

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UltimApe@ultimape6 months ago

Using RDA of zinc for adult male, 44 mg/ day would allow you to cum 100 times and still have 100% dv left over. Is it safe to eat that much zinc? https://t.co/peAQ13UtAe https://t.co/Gm4qmDdgFz

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