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š§µ Thread (92 tweets)
"We hope to find an intervention that can help people who are at risk for cardiovascular disease because of their work and sleep schedules."https://t.co/rsj64m5AP1Rat Sleep Microbiome High Blood Pressure Heart Disease
"In this review, we compile the recent findings and hypotheses describing the interplay between the microbiome and blood pressure"https://t.co/uRsCpg0z1P
"Hypertension could be the driver of heart attack and stroke in patients [...] research suggests a connection between periodontitis and hypertension and that dental treatment might improve blood pressure, but to date the findings are inconclusive." https://t.co/bFNestTka0
"review throws a light on possible enigmatic link between AD and periodontitis. This review is designed by collecting data from PubMed database using key words like āAlzheimer's diseaseā, āinflammationā, āperiodontitisā, and āproinflammatory cytokinesā." https://t.co/X8kONU0wBW
"AĪ² has also been recognized as an antimicrobial peptide participating in the innate immune response. [...] Importantly, bacterial amyloids through molecular mimicry may elicit cross-seeding of misfolding and induce microglial priming." https://t.co/CM1O9GRzl6
"recognition that periodontitis is associated with a number of important systemic diseases, include cardio/cerebrovascular diseases, diabetes, respiratory diseases, gastric ulcers, rheumatoid arthritis, obesity, cognitive impairment and even cancers"https://t.co/ocY6M74Joo
"To my luck, I stood next to a sake otaku who also happened to be a scientist. Once standard platitudes were out of the way, I mentioned my newfound learnings"https://t.co/9MYaEAO4sf
Old people with perturbed gut microbes might smell funny.I wonder how many doctors have sub-clinical pellagra.https://t.co/vsAxKIkWHo
So of course the bacteria in your mouth are different if you are sick, young, or you have changes in your microbiome driven by hormones associated with immune function.Like the ant. https://t.co/T9sYGGzURbhttps://t.co/3nGM6mfqCs
We try to keep our gut bugs in check. Some of us struggle with this."Interestingly, around 20 percent of humans lack a functional gene to produce L-fucose, a problem that has been associated with the inflammatory bowel ailment known as Crohn's disease."https://t.co/7N394YSbdJ
"It can be concluded that there is no clear evidence for the causes and treatment of dry mouth, therefore the majority of the general dental practitioners refer most of the cases to appropriate specialist. Treatment must be individualized"https://t.co/mjruPQayYm
Somebody thinks the water in your eyes is driven by overall body water.https://t.co/sj8bHyEFg5I wonder how many people with dry eyes don't realize it's an immune system issue by making the same assumption.
Rheumatoid Arthritis can exhibit dry eyes due to your immune system attacking tear ducts. Later on, the development of scleritis would be seen as just a result of someone's chronic dry eyes. People would be telling them "just drink more water, you fool" and would be wrong.
When looking up other genetic factors in my 23andMe that might indicate M.S. as a misdiagnosis, I found Rheumatoid Arthritis genes and Sjogrens Syndrome genes. They all get dry eye and dry mouth sometimes.https://t.co/DTpiA1rAJ9 https://t.co/WCDlOOuDfk
Why would all these immune system associated problems mimic each other?Do you you think you can detect it from spit like in this autism saliva test?https://t.co/tHTTy5Z1yh
When people ask me about how I used 23andMe and what the experience was like. I'll talk to them about how it can be hard for some people to generate enough spit for the DNA sample kit to work.I should figure out how to save my spit.https://t.co/Tm2FhUehlB
Have you ever wondered if spitting is actually a bad habit?https://t.co/xj0fE7WQRe
Everybody is telling me that hand sanitizer is bad and I thought about it for a while.Then someone said a derivative of "a cat is fine too" and I had ideas. Not all of them are appropriate.Long story short: I'm now reading up on spit's antiviral activity & oral microbiome. https://t.co/qBYPiSZgm9
Bees make wine with their mouth. We call it honey. They even have a special organ specifically for the storage and fermentation of sugars.https://t.co/5pkbwDyK7G
For every nugget of insight I drop in my tweets about bees, I have to consume and spit out about 50 trash websites like this: https://t.co/MWK3ua8H3j to mine them for diamonds of truth within the nuggets of misinfo, bias, and absurd snakeoil bullshit. Even then, I'm likely wrong.
Steven Universe is a Jesus Allegory.https://t.co/QYgCSRpQJx
I made this connection via learning about Ancient Egyptian SpitWhat if Steven Universe is actually a Thoth Allegory, and I'm just projecting my western bias?https://t.co/ETUdrZRKb0
Making rice wine on the moon with help of the shrine maidens?Tsukuyomi -> the shinto moon god of japan.Ever notice how some alcohol can induce psychosis.Things come alive if you drink and are susceptible to the spirits.Metaphorically speaking.https://t.co/bD4iJwOSKd
@chrylis @selentelechia @eigenrobot @sonyasupposedly Fermented chocholate mochi. Rice wine. I suspect that the food of the gods is some kind of tincture made with a fermented food product. It's fascinating how often the moon is made of cheese.https://t.co/RWGq0wNJtl
I'd half expect the rituals around rice purity in sake making are founded in what happens if you make rice wine out of a bad batch infected with Ergot fungus.https://t.co/Z2dLqdHwed
I'd also half expect rituals involving dousing objects with rice wine vengar as a sort of religious cleansing mechanism.Dunk toys in alcohol to pay respect to god of life. Might also stop common cold/scare away disease bringing demons that possess them.https://t.co/e8JUkhEuHS
Why would they call this after the moon rabbit?Because it is always chewing on that mochi.https://t.co/sFKGVLsrIg
If we make cheese out of calf rennet, what do you think we would make out of herbavore spit?https://t.co/skun1c5ckj
I've been trying to find bacteria that produces enzyme to allow rabbits to eat insects. They don't produce chitinase so they're likely not insectivore.They can eat meat tho https://t.co/FWKp9Uh6MjOddly humans can't live off rabbit - not enough fat.https://t.co/iXRht3UcMM
Someone I'm following made a joke about how you can chew on apple sauce. I wonder if they were making a veil'd reference.https://t.co/bUJ8s5QaRZ
Trying to figure out why spit sometimes smells really really awful.https://t.co/ESPgTU26EJ
"major scent compound that plays a role in these interactions is indole. It is the most prolific nitrogen-containing volatile found in the petals of flowering plants and it is biosynthesized and emitted from the flowers of over 30 distinct plant families"https://t.co/jFXPDH09No
There are some weird ties between Parkinson's, microbes, sleep, and the eyes. It always spooks me whenever I learn about it again.https://t.co/Z2ZaYvFpEl
People telling stories about how jesus spit was a kind of symbolism & miracle. Ignorant of spit's use as a healing mixture in ancient culture?https://t.co/UxoNnwToULI wanna find a biblical scholar who's exploring oral microbes. Surely this must exist?https://t.co/a76GSwwBP8
I mean, I'd love to get shit from an actual historian on the nature of disease from the middle age while i'm in the middle of learning arabic to double check rhyming slang theory from Avicenna's texts on medicine. Cunningham's Law and all that.https://t.co/uG7PK3BwlV
It's amazing how the entirety of western native culture's use of fermented foods was quickly labeled under one term by the Spaniards when they invaded. https://t.co/07gauymC40So many missing ideas about spit.https://t.co/diear5FZJi
All of our modern framings of alcohol are based on english custom and law.I wonder if the Aztec warriors used a form of proofing to tell if their chocholate wine was legit.https://t.co/k7IbuWxWIsI bet this is also a drink of the gods.
"The Day of the Dead used to be held in the middle of the Aztec year, but once the Spanish arrived, it was moved to occur on All Saintsā Day, merging some ancient Aztec beliefs with a dose of Catholicism." https://t.co/VN8gxlKlEj
Moon gods everywhere."the very important role played in religion by the gods of drink and drunkenness, those who were called the Centzon Totochin, the lunar and terrestrial gods of plenty and of the harvest, as well as Mayauel, the goddess of the agave."https://t.co/A4L6m9qokj
I wonder if you can bootstrap the fermentation of cacao by chewing it to help the lactic acid bacteria in.https://t.co/tGA7gB54PShttps://t.co/N8iSPclY6v https://t.co/oMpZ1BzsyT
Yep, the drink of the gods from south america was probably also originally made with spit."The reason Pulque appears here is because it has been told that authentic Pulque is fermented from the spit of people who chew the maguey plant"https://t.co/caeUmixnDv
A healing plant too. Fascinating.https://t.co/3SWjolFVkV
Loss of traditional spit drinks?"with Parkinson's disease, the opposite is true; age-standardised [Disability-Adjusted Life Year] rates due to Parkinson's disease increased with [Socio-demographic Index]. The reason for this association is not clear."https://t.co/Ki536vmP4u
"Recent reports indicated that chronic consumption of coffee leads to reduced risk of Alzheimerās and of Parkinsonās disease"https://t.co/gU1jixHaj9Why?
Good to know about Theobromine poisoning.That would be bad, lol.https://t.co/5StLkrnZt8https://t.co/DrzypFxwSm
Show me your spit, I'll show you a mirror to your health.https://t.co/5wfd0pUYwa
Moon rabbits everywhere."In Aztec mythology, the Centzon TÅtÅchtin (Nahuatl pronunciation: [sentĶ”son toĖĖtoĖtĶ”Źtin] "four-hundred rabbits"; also CentzontÅtÅchtin) are a group of divine rabbits who meet for frequent drunken parties."https://t.co/FyO2dkpIfE
Show me your spit, I'll show you a mirror to your health. https://t.co/8SqjMNLkM2
"as the two families of Norse gods (Odin and Freyr) made peace, they "spit into a bowl". [likely] a reference to the Germanic tradition of crushing berries in your teeth and spitting them into a bowl, then allowing them to ferment."https://t.co/WMLVSa5coohttps://t.co/gXxkg0xoiI
"The Swedish nationwide registerābased IBD prevalence was higher compared with previous Swedish and international estimates."https://t.co/jUhlSCuCZ3huh. I wonder what is changing.https://t.co/flEB9m3WYt
"... lots of the Swedish chefs, they make their own wine, they have their own beer, they have their own pots and pans and so on, [...] But I thought [I'd] go for something very eccentric; I go for my own surstrƶmming."https://t.co/ywV6BMPK5Uhttps://t.co/gLj72Px6pE
Might explain why I like Indian food?"also believed that the Vikings chanced upon cardamom, another spice native to India, via the Venetian route and their descendants have been using it in their breads and desserts ever since."https://t.co/lTMdslVKaRhttps://t.co/yaYZhAOnhM
A non-spit based Chicha that uses sprouted corn!"plants store starches in their seeds, and then when the little seeds start to sprout, they make some enzymes that start to break down the starches into simpler sugars that the tiny little plant can use."https://t.co/I7XIUJRGyL
Impressive:"ruins of Moray are not quite like the Inca ruins we usually encounter ā Houses, temples, fortressesā¦ In fact, It is believed that Moray was used by the Incas as an agriculture research station. It is at least the most widely accepted theory" https://t.co/kUJ8jpV8jf
The "Teef!" oral prebiotic is basically a nitric oxide + microbe booster for dogs.Doing it once a day because I can.https://t.co/Yd6FIRL92n
There's a good chance I can predict if someone has erectile dysfunction by the amount of nitric oxide in their spit combined with other factors related to diabetes and saliva production.https://t.co/1L1TiRiq0ghttps://t.co/SCwb5BrfcX
There was a weird shift in the space of alcohol production that coincides with the anti-witchcraft moral panics among the west. I think this is when we lost the cultural knowledge. https://t.co/ZHZj1Wqy8z
"Part food safety policy, part religious suppression, and part marketing scheme, Reinheitsgebot (aka the Bavarian Beer Act), was implemented in 1516 by the German government and the Holy Roman Empire."https://t.co/VQPkgkJmcq
"Why is it that early modern Europe had such a fervor for witch hunting? Between 1400 to 1782, when Switzerland tried and executed Europeās last supposed witch, between 40,000 and 60,000 people were put to death for witchcraft"https://t.co/X8yJDr256w
I wonder if you could spike a spit-based Blaand with fungal spores much like natural kombucha is alcoholic.https://t.co/2Hg3qeUYUq
> "Our study positions saliva as a viable fluid to monitor immunity beyond plasma to document COVID-19 immune, inflammatory, and coagulation-related sequelae." https://t.co/L8hmHZeQX0
My spit smells bad.https://t.co/UHcUn9bH6b
Still haven't figured out a way to fix my teeth.https://t.co/eVaeYIETt4
Oh hey, It's me. I'm building a microscope. :3https://t.co/plmrXwmV4g
Does anyone know how to measure immunoglobulins in spit without having live virus to test against?https://t.co/mLnLHQTeaQ
"Oh, there must have been some magic in that old silk hat they found" š¶Superstitious beliefs that spitting in a hat can help protect you from demons and give you good luck.https://t.co/nfp4gvACR6https://t.co/vue7mdNA1b
Ah yes, magic. What we call rituals we don't understand."Several Native American tribes have longstanding beliefs that spitting in a dogās food is how to get it to bond with you." https://t.co/N3aaihzkQR
"linked premastication to the spread of HIV, hepatitis B, dental caries, and syphilis from caregiver to baby. But beyond single-pathogen studies, [...] its possible role in nutrition, immune health and parental bonding remains woefully scant." https://t.co/SxCZLN4h1t
Is it possible that swapping spit with someone who's survived infection would help train our immune system somehow? I'm not talking about variolation, but microbial inoculation.https://t.co/eHdlt3YoXQ
If I can measure IgAs etc at home, the maybe I can also use it to figure out how to tame food allergies somehow?https://t.co/oAI6ZJKh63
"Clinical trial shows encouraging results with fecal microbiota transplants for peanut-allergic patients" [2022]https://t.co/rNTX6lFxqnThats fun.https://t.co/9dEjlMmY22
You know...I haven't had a single allergic response since my FMT in January. I wasn't able to get the everlywell food allergen test done cuz it was so hard to draw blood for the viome one.Would be neat if it impacted my spit.https://t.co/xZW8gWuXMw
imagine If I cure my allergies by eating dog shit... because I steelmanned a theory about EMF and guessed that it was an alternate model for explaining unknown metabolic and oxidative stress factors related to gut microbiota problems. š¤£https://t.co/tKjeZOC26s
*grins*https://t.co/QozR0fM9Ts
@s_r_constantin This is why I focused so much on spit."Here, we show that oral epithelial cells respond to viral agonists by preferentially inducing Type III IFNs (IFN-Ī»)." https://t.co/K7Px5riSlEI have been actively upregulating the way my body fights viruses for 2 years now.
One must wonder, why was consumption so bad in the cowboy era? If it is spread by spit and lung mucus, was it because their spit & lung mucus wasn't fighting it off? https://t.co/G1YK5qZafl https://t.co/qQTZFzBblG
ha, haha, ahahahaha, hahahaahahaha."NAC treatment in M. tuberculosis-infected human macrophages resulted in a decrease of oxidative stress and cell death evoked by mycobacteria."https://t.co/T1gLfve1iO
Arthur Morgan should have eaten more garlic.https://t.co/abxYdQhqJo
"Eradication of oral bacteria through antiseptic mouthwash or overuse of antibiotics causes blood pressure to increase. Allowing recolonization of nitrate- and nitrite-reducing bacteria can normalize blood pressure." https://t.co/VE5oSztycBhttps://t.co/VAn3iLLkTh
@OhMalG @no_identd There's a whole loop where the body absorbs stuff in the gut and then sends it back to the oral cavity to recycle nitrate. This is something that becomes impaired in crohn's due to poor gut function.Maybe you were getting that effect?https://t.co/1vWs6bWZqL
"some may have direct benefits from nitrate as a prebiotic as their microbiota naturally reduces significant amounts, while others may benefit more from a symbiotic combination (nitrate + nitrate-reducing probiotic)." https://t.co/gpYlsw7yVo
Sure is funny what happens if you eat cow dung.https://t.co/9wjE2UsWyP
"Panchagavya or panchakavyam is a mixture used in traditional Hindu rituals that is prepared by mixing five ingredients. The three direct constituents are cow dung, urine, and milk;"https://t.co/w4fvAJJ5dIWanna bet this is fixing nitrate function in the body?
Remember folks, there is no evidence (that traditional ayvuredic methods like) drink cow urine will fix you.never mind that we've been ignoring the role of microbiota in health and disease for most of the past 150 years other than to eradicate them.https://t.co/laoRaj5HE4
My ideas are as old as the history of medicine."Sumerian doctors were the first to use uroscopy as depicted in graphic clay tablets (4000 years bC)"https://t.co/LwXH7bw1LYhttps://t.co/JEPWDTNmjw
@__a__chimera__ I ask myself, "Why would that guy seem to assume 'drinking grandson's pee really helps' like it was obvious, and that it would be dumb to drink non 'clean' pee?"Maybe Nitric oxide & urease associated bacterial effects prevent damage and oxidative stress?https://t.co/3xv4UKgs7z
"In any case, remember Pliny's advice ā spit into your urine immediately to prevent anybody from cursing you." https://t.co/i1TjHikIwR
Why would inoculating urine with oral microbes prevent you from being cursed? Would urine used as fertilizer allow someone to taint your crops without you knowing it? Is the urine acting as a bacterail prebiotic?Did they spit on witchcakes? https://t.co/JFqSpeRW32
Witchcakes: feed bacterial metabolites from urine onto a piece of unleavened bread mixed w/ specific herbs & plant fibers. Resulting fermented product, when fed to a dog, acts as a medical test for pathogens that impacts it's microbiome.Church didn't like personalized medicine.
What happens if I spit into milkbread laced with urine and feces.Would it become alcoholic as my oral microbes can ferment dairy? https://t.co/tSdJUXBkrlhttps://t.co/y7stQ8QaVb
"Paracelsus is said to have cured many persons in the plague-stricken town of Stertzing in the summer of 1534 by administering orally a pill made of bread containing a minute amount of the patientās excreta he had removed on a needle point."Bread fermented w/ feces? wild.
Retvrn to tradition. or something.https://t.co/hHi07aXJYA
