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Cube Flipper@cube_flipper• almost 3 years ago

given the @slatestarcodex shoutout yesterday, I'd like to post a thread about how the inverse can also be true: how psychedelics can put anti-annealing, or work hardening into your neuromuscular system https://t.co/pQJ58sJh2o

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Cube Flipper@cube_flipper• about 3 years ago

muscle relaxants that Actually Work is a big untold story in psychedelic-assisted therapy imo https://t.co/leWo0sIVvl

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Cube Flipper@cube_flipper• almost 3 years ago
Replying to @cube_flipper

throughout these explorations, I have found MDMA and 2C-B to be far more effective muscle relaxants than LSD, psilocybin, DMT. 5-HT1A vs 5-HT2A agonism...?

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Cube Flipper@cube_flipper• almost 3 years ago
Replying to @cube_flipper

it seems like while all of the above afford the neuroplasticity required to rewire the body map, the former two also 'round off' sharp stimuli (pain) in such a way that the energy can be dissipated efficiently without causing more trauma

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Cube Flipper@cube_flipper• almost 3 years ago
Replying to @cube_flipper

my spit test of these analgesic properties is that on MDMA/2C-B I can swish iced water over my teeth. this would normally be extremely painful but in these states it results in a vivid sensation which is not exactly 'pain' per se

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Cube Flipper@cube_flipper• almost 3 years ago
Replying to @cube_flipper

okay, I now have two cautionary tales around DMT. so I was messing around with DMT in my room at night. during the come-down period I noticed a big wolf spider in my bedroom. I like spiders and decided to get a glass and help it out the window https://t.co/ePshhxpzze

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Cube Flipper@cube_flipper• almost 3 years ago
Replying to @cube_flipper

as I was doing this, I mistakenly thought the spider ran up the arm of my robe. I flinched violently and stripped the robe off (the spider was nowhere to be seen).

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Cube Flipper@cube_flipper• almost 3 years ago
Replying to @cube_flipper

doing this while still on DMT put this dense pattern of contraction throughout my right latissimus. I was struggling to use my right arm for a few days. I figured the poison might also be the cure and tried massaging it on DMT but only managed to shift the contraction around.

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Cube Flipper@cube_flipper• almost 3 years ago
Replying to @cube_flipper

eventually I got my friend to attack it with a massage gun and it worked itself out.

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Cube Flipper@cube_flipper• almost 3 years ago
Replying to @cube_flipper

the second story: so I was messing around with DMT in the bathtub. said bathtub was a little too small for me and I was lying such that my neck was contracted. I think you can guess what happened.

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Cube Flipper@cube_flipper• almost 3 years ago
Replying to @cube_flipper

during the come-down period, I felt all the muscles in my neck contract as one, and stay that way. I swear I got a full centimetre shorter in the space of a second.

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Cube Flipper@cube_flipper• almost 3 years ago
Replying to @cube_flipper

it was *very* dense and nothing I could do over the next few days would fix it. I actually became quite distressed as it felt so uncomfortable.

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Cube Flipper@cube_flipper• almost 3 years ago
Replying to @cube_flipper

but, I guess there's nothing that can stop me, because a few days after *that* I was hitting the DMT pen again, and I yawned, and suddenly my neck was free to move again!

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Cube Flipper@cube_flipper• almost 3 years ago
Replying to @cube_flipper

I guess the point of these two stories is to demonstrate how I was able to accidentally traumatise and then detraumatise my neuromuscular system in a fairly simple way under the influence of psychedelics. Scott said it better than I could: https://t.co/3WJjytbQjS

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Cube Flipper@cube_flipper• almost 3 years ago
Replying to @cube_flipper

I should add that I find myself reluctant to use the word 'trauma' in this context – it's too emotionally loaded. I think I prefer the term 'work hardening' instead. it's a bit like annealing's dual. https://t.co/mTEJ5MVFqV

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Cube Flipper@cube_flipper• almost 3 years ago
Replying to @cube_flipper

in any case, what I hope is that neuromuscular work hardening may prove to be a more practical/ethical target than psychological trauma for research into psychedelic-assisted therapy.

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