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🧵 Thread (69 tweets)
I miss you @OhMalG.https://t.co/68jXLESPct
I made a twitter list with all the people I search thru when I want to learn from.I keep seeing replies from youhttps://t.co/ABsLruVXht
I have Hyperthymesia. I will literally never forget you.And I plan to live a very, very long time.https://t.co/mmowjyIDJw
The people I want to help are those like me.The people I am most like to become close friends with are also those who are struggling.Shared experiences forge a close bond. A sort of kinship by proxy. This means I will loose more friends in the future.https://t.co/sbOXbmkZvL
I need to eat more shadows.https://t.co/cImdXFCqo2
I will forever be trying to cure someone who has already died.https://t.co/Ng3RhWhE3o
She's one of the people I keep in my head when I tweet."What would mal think about this?"If she would have liked it, I'd post it.https://t.co/srPbWomnEa
I think about this a lot.https://t.co/rIZwtTDOny
How do I fix your eye?https://t.co/hhzkZ764pk
What is wrong with your eyes?https://t.co/O7QV2lTPVt
make mmmalign healthy again. 😥https://t.co/V51kpiXJmm
Bumping a DM in my list like some kind of necromancy. https://t.co/Y56jXmJZhH
Hearing this song made me remember.https://t.co/LQ1VGtMzN0
Microsleephttps://t.co/KuMwaEdR9p
I need to cure narcolepsy. It rhymes with necromancy. https://t.co/3az6D59qpD
Iris. Black like a demon's. Blackout eyes and blackout memory.Infection?"[Sleep modifies anticholinergic mydriasis]"https://t.co/LQbr16I97u https://t.co/AX1HQl6HlR
The girl with anime eyeshttps://t.co/KuMwaEvs0X
megalocorneahttps://t.co/CpxojyL8QT
Demon of the eye.https://t.co/iCgC1iWl3R
She was riddled with cancer.https://t.co/gouOrR3fS2 https://t.co/HV7llYal2I
I spoke with her of the Demon of the blood. https://t.co/Sp0UmTHZje
She was trying to recover her memories.https://t.co/EfTfWS2Ijp
Her brain had been broken.https://t.co/yQRclmQndr
no. Someone had broken her.https://t.co/XcB9IQWsBC
Broken her immune system.https://t.co/uSBXNnIakI
Broke her gut."Here, we show that orexin activates the mTOR pathway, a central regulator of cell growth and metabolism"https://t.co/LZtZL4nnmR
none of you are free of sin.https://t.co/kbRfHNfLRe
To sleep, perchance to dream.https://t.co/xszAdm9dtx https://t.co/ANSfk7NJLS
Raise the dead.https://t.co/GAm87sdxzh
First thing she did was explore my genes and try to help me feel better. It's weird how I replied with tweets about narcolepsy. https://t.co/x3P9SBqmRY
I made a channel in my discord so we could talk about pharmacology there. She's one of the first people whos tweets I search when I'm interested in how a drug might be working. https://t.co/lkmGUJZezn
We spoke a lot about how bodies develop and how brains form.https://t.co/gPD5oZ6Ung https://t.co/uoKVUbP587
Powerful memories https://t.co/G7nbSkdunJ
Sometimes the signpost are entire people. Ideas flood back to me - anchored to strong memories of them. Hmm, so @outdreamer is related to the idea I'm looking for adjacent to "signposts" and then @monk51295 pops into my head in my head. https://t.co/XmbycVxIhx
We had some neat discussions on "Closed Eye Visualizations" late in September. She was having increasingly bad sleep problems the past few months. https://t.co/zWV74yChpR
I've come to learn that my experiences are very non-standard.Its weird to me.https://t.co/nZKxtKWWLh https://t.co/22n6jZxLoG
"only appeared during LSD consumption and continued after LSD suspension, namely, Hallucinogen Persisting Perception Disorder (HPPD) [...] not cause a major functional impairment but provoked sufficient worry and concern due to its persistent continuation"https://t.co/qmu3PoAYg3
She was describing the impact of the antipsychotics she was being drugged with. She was describing a lot of the things that I've been experiencing my whole life sans drugs.https://t.co/EhcZKaT5Zy https://t.co/TErDZhOgBg
I think the meds she was on + the sleep disorder and immune dysfunction from the ECT was hurting her. https://t.co/IhW3L6kRNv
If she was here, I'd talk to her about how she was having chronic fungal infections might have been diabetes induced by ECT and the antipsychotics.https://t.co/SHRE3658QM
"Acutely, ECT increased insulin resistance and requirements, necessitating substantially different insulin doses on ECT days compared to non-ECT" https://t.co/Mt9N7DYHW9
"After each administration of ECT there was a significant rise in blood glucose and plasma insulin levels, both of which peaked at 15 minutes." https://t.co/iJCOG4SuxN
"conflicting data in the literature about the effects of electroconvulsive therapy (ECT) on blood sugar. In general, glycemic control and insulin requirements show no changes over a course of treatments, although there is interindividual variation." https://t.co/57A0ynXWwC
"The exact incidence of brain damage remains unknown. If brain damage is defined as memory loss persisting at least 6 months after the last ECT, findings range from 12% to 55%."https://t.co/jYpZ8DPm8xhttps://t.co/2OXsrCS2W9 https://t.co/upmrgL1QgD
Do this.https://t.co/PVdhpUJKq8
I would bet my life that ECT's impacts on insomnia and sleep outcomes tied to effectiveness on depression are also correlated with inductions in of narcolepsy in a small proportion of people.And it's really immune disruption and mitochondrial / metabolic shifts tied to gut.
Stop electrocuting people, you ignorant fucks."Interestingly, a case report has shown changes in gut microbiome bacterial populations during a course of ECT." https://t.co/35tqus8BvW
Fix your gut.https://t.co/c8kOTN4yLk
Why is Swedish candy so salty? I got a goodie bag along with my Surströmming. https://t.co/K9ubWmgnF9 https://t.co/fLKdfQwwOb
I will also try thesehttps://t.co/61a7zaTqcD
She saw something in this Bouquet of flavor.https://t.co/WEFQbeIB1r
One of the reasons why real honey is important is for the same reason why "mad honey" exists:https://t.co/AbqnxGvOK4The bees are doing more than making a sugary substance. They are creating tiny medical tinctures by eating certain flowers.https://t.co/CyetpBQbZr
I want to understand the smell.https://t.co/sF5FJHH8Tw
There's a genetic factor that changes how people sense and respond to smells."gene variant that influences how strongly a person perceives rotten fishy odors. [...] identified gene variants associated with the intensity of licorice and cinnamon odors."https://t.co/pUV5svfdp7
Stink fishhttps://t.co/IZWvey0eHo
@MimeticValue Possibly related is a urea rich fish delicacy being somewhat normalized in their culture. ( I personally love fish sauce, but stinks like heck if I eat enough of it. ) https://t.co/AHLArRZ6yrWould have big impact on gut microbes.https://t.co/QoZOL5f1oB
Stinky Fishhttps://t.co/2vHihl0dNB
Stinky fermented fish."These bacteria produce carbon dioxide and a number of compounds that account for the unique odor: pungent (propionic acid), rotten-egg (hydrogen sulfide), rancid-butter (butyric acid), and vinegary (acetic acid)."https://t.co/2TLrK3s3c4 https://t.co/A8DYXsmgGc
Figured out how to treat your narcolepsy by talking with a bipolar guy about his avolition and how it impacts opioid system & metabolic pathways tied to chronic fatigue. Please wake up.https://t.co/PTd0g38Cb6
via science direct's page on beta-endorphin."when opiates are decreased and noradrenergic activity is increased, PTSD symptoms may become acutely exacerbated. In fact, many symptoms of PTSD are similar to those seen during opiate withdrawal." https://t.co/GsUYYsqcs4 https://t.co/JYs19fTN7C
I think fixing orexin signaling via gut health factors tied to energy drink ingredients could explain self medication for fatigue and sub-clinical narcolepsy."The role of orexin-1 receptor signaling in demand for the opioid fentanyl"https://t.co/UZors9eJns
What, you didn't realize ECT can fight gut disorders? You thought it was doing stuff to the brain? You're silly. It's clearly messing with gut and immune function given it fucks with insulin.https://t.co/tKKYADfwx2
I learned that from watching an episode of houses where he gave himself insulin shock treatment to stop seeing hallucinations of a girl. https://t.co/eQMyorTEck
"Amber began mocking and tormenting him. She also reminded House that every option would be terrible for him: Schizophrenia meant that he could never work again as a physician, while Multiple Sclerosis or stopping Vicodin would cause him severe pain."https://t.co/zKWh1Cz5rn
Mast cells? Why do I keep running into an idea about mast cell activation helping fight Alzheimer's related sleep walking.https://t.co/HnyMMdQfQG
"explore the molecular mechanisms underlying TTR activities at the cellular level, and suggest that these might go beyond its most acknowledged carrier functions and include interaction with receptors and activation of intracellular signaling pathways."https://t.co/NCxYNSdqZb
"Familial ATTR amyloidosis is an inherited disease, where the body makes a mutant form of a protein called "transthyretin." Transthyretin is abbreviated "TTR" and is the reason this disease is called familial ATTR amyloidosis." https://t.co/IyUkgAbaF3 https://t.co/VmtY80bzSY
Learning about how TTR-FAP may mean trouble ferrying around Vitamin A."This protein transports vitamin A (retinol) and a hormone called thyroxine throughout the body."https://t.co/9gUVhqEXWwI wonder what else can modulate thyroid hormones.https://t.co/wtRu32MijD