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Society likes to normalize. I'm not normal. But that's why friends should be: Celebrate & understand differences leads to wider & deeper experiences. We can disagree, but curiosity empathizes. 🎂🎂🎂TAKE MY BIRTHDAY WEEK QUIZ 👇 & SHARE THE CAKE 🎂🎂🎂 🧵 to quiz yourself:
I have raised $2.7 million dollars, met 5 billionaires (Bezos, Thiel, ...). On paper, I'm *supposedly* worth $10M+. But I don't like money things, I like frugality & efficiency. I take the bus, slept in parks. I feel uncomfortable in rich settings.
I can hallucinate any sensory experience on demand (taste,touch,sight,auditory,smell), including memories back to age of 2, & am constantly experiencing "trips" beyond sensory. I have never done drugs. I'm caffeine sensitive, crash from it, throw up from anything worse. Sober.
@marknadal I reactivated memories of faces earlier this year. Lived my whole life not being able to recognize people. Suddenly just turned on.I can remember the smell of the bathwater from the time my dad put me in the tub when I had my socks on. I was 2.
@marknadal 5 sense synesthesia reactivating like when I was a child has also rekindled my memories. I didn't even know I had memories of faces in there! It's wild.https://t.co/ehAQZGFrXM
@marknadal I want to know what your gut bacteria are like. https://t.co/xGuBBaEqtK
@marknadal Wild how great twitter is at connecting similar people together.https://t.co/5keLmtT7kt
@marknadal I wonder how much of what is considered "normal" is actually due to large scale forces in our society. In America we had endemic pellagra from like 50 years due to our use of corn and poor nixtamalization (niacin).Mine was driven by a GI disorder.
@ultimape I'd guess it's in the spine https://t.co/Jyx0KNiy5z
@Aella_Girl In the womb our brains develop *structural* understanding it is all organized, geometric, logic space. Like what most of computer science works with. Birth thrusts us into *DISORGANIZED* space, things haphazardly placed. Drugs turn off that, take you back to fractals. 👇
@marknadal Studying how gut bacteria produce serotonin/dopamine/gaba/glutamate to try and figure out what healing drugs are doing to the body.I heard Ayahuasca can cure diabetes type II and reverse Multiple Sclerosis / Crohn's. I wanted to know why.
@marknadal In 2018 I cleared out my gut with an aggressive fast and it cured my anxiety and major depression, but the underlying crohn's returned and reignited autoimmune symptoms. I ate dog poop in January and haven't had symptoms since. That was when my memory returned.
@marknadal I lost my ability to do math and think deeply on visual ideas. That returned slowly as I worked on gut health and then went up stepwise as I did those drastic things.I think its largely by fixing blood flow in the brain.
@marknadal There's stuff that flows thru the blood that can impact blood vessels in the brain (smooth muscle tissue). Pain signals in the gut seem to trigger the flow in the brain to constrict. Its like I was constantly feeling tired brain fog of being sick.
@marknadal With poor nutrient intake from crohn's + blood flow restriction over time this starved nerves & I eventually stopped being able to walk. This seems to be what relapsing remitting multiple sclerosis is in my family.Fixed my gut... it's like I woke up for the first time in years.
@marknadal Ayahuasca => gut bacteria modulation.https://t.co/XV3kLZ2w6a
@marknadal I ranted at length about mathematics and IQ in the context of how society is missing the role of gut bacteria in this space.https://t.co/ZFNppEJqSX
@marknadal It is the spine, but it also isn't. I now harbor gut bacteria in me that make choline and niacin for me. These impact vagus nerve function & remylination. Allowed my gut to speak more clearly to my brain. I haven't felt Derealization in years. https://t.co/Jqi6pa6sAI
@KimStephen2240 @bradstradamus @AutismCapital My understanding is that vagus tone is a key facilitator of the gut-brain axis acting to promote oxytocin response from serotonin receptors in the gut. My vagus nerve was bad due ot M.S. Myelin problems. There are studies showing it can be bad in general for autistic types.
@marknadal But also so many chemicals that fuel brain are flowing thru blood, but it starts in the gut. The vagal nerve's role in the gut brain axis is to tell the brain what the gut bacteria are doing / let it know it's safe to open up the blood-brain-barrier to let nutrient in. Gut frens.
@marknadal I saw @alexeyguzey has been experimenting with this himself. My 4hrs / night happen during the winter months.https://t.co/ljkqrQ41EF
@marknadal @alexeyguzey Since writing that post, i've since completely absolved my non-24-hour disorder and have been waking up at 10:30 am on the dot nearly every day without an alarm clock. I suspect it's this: https://t.co/ToCRahvlTs
@marknadal @alexeyguzey My ability to produce butyrate and heal DNA damage likely play a role in need for sleep and weird sleep issues. Since writing about this, studies showing hippocampus memory formation requires DNA breaking and healing. https://t.co/BEejMw5OlF
@marknadal @alexeyguzey I believe sleep is really a factor of toxin clearance tied to microglia and astrocytes. Acting on this space via gut health is what I've been focusing on. Intersection of autism, Alzheimer's, and multiple sclerosis. & regulated by gut health. https://t.co/6JrzcwxyeL
"identified autism-associated abnormalities in cells that support neurons in the brain and spinal cord. [...] autism brains, the microglia appeared to be perpetually activated, with their genes for inflammation responses turned on."https://t.co/qYY4JhowKBhttps://t.co/PPNWAjebUo
@marknadal @alexeyguzey On linkedin @HealthUnveiled just posted a gerat summary of the sleep side of things:https://t.co/65FnUxMEmV
@marknadal @alexeyguzey @HealthUnveiled One of the challenges is that most of the sleep studies are not looking at people like me. They focus on "normal".https://t.co/XfdeZcOSWg
@heniek_htw @Grimhood > 71 healthy adult menI wish these kinds of studies didn't default to healthy adult males. In autistic types, sleep (& cortisol) is quite screwy and may be a factor related to gut health. IL-6 being a major player in intestinal diseases. https://t.co/6Ime9Tml8G
@marknadal @alexeyguzey @HealthUnveiled Just like Freud's early investigations on autism were biased to young boys. We keep committing the same mistake in how we do science. Studying people under a lamppost cuz that's where the light is. https://t.co/cxvma8JgVO
@Outsideness @officialmcafee I figured out why sleep causes memory consolidation partly by figuring out how the gut aids in sleep and it's ties to cognitive decline from cocaine. Probably explains why freud had weird sex dreams about his mum. https://t.co/fSPU1OGsvB
@marknadal @alexeyguzey @HealthUnveiled It's amazing how a little gut health will fix issues like insomnia.https://t.co/KI6sk2JqhT
@truewesterner @FrontPsychiatry I've been going thru sleep disorder studies to try and locate changes in my gut that might have correlated with durable remission. This study seemed to do a good job for measuring insomnia. Notably, Eggerthella eventually went away for me after FMT. https://t.co/4z9ke8wof6 https://t.co/GXT5NJ05jK
@marknadal @alexeyguzey @HealthUnveiled The doctors that treat conditions with chronic insomnia have no idea what they are talking about. It's so upsetting.https://t.co/w1skR296zj
@RyanMarino How can I keep pulling these out of my ass? Cuz I know more about your field of interest than you do.Suvorexant is an insomnia drug..."The study findings may support the development of more effective and precise treatments for insomnia." [SEP 2024]https://t.co/7EuotZHHtY
@marknadal @alexeyguzey @HealthUnveiled I'm living proof that gut health shifts can impact sleep.But afaict we are blind to this space.https://t.co/TileKxT0rC
@marknadal @alexeyguzey @HealthUnveiled I wake up at 10:30am everyday to pee.https://t.co/zHToCvwz8o
@RogerSeheult The bacteria's cortisol activates a stress response that restricts blood flow in kidenys & drives bladder contractions via simlar aciton on bladder smooth mucle. The bacteria, entrained to sleep cycles, want us to wake up. They make us have to pee.https://t.co/NLRRg1xfdu
@marknadal @alexeyguzey @HealthUnveiled We need to study the weirdos.https://t.co/fsVM9eHyDt
@marknadal @alexeyguzey @HealthUnveiled "Celebrate & understand differences leads to wider & deeper experiences. We can disagree, but curiosity empathizes." 🙏👏https://t.co/UE8VwXOutG
Society likes to normalize. I'm not normal. But that's why friends should be: Celebrate & understand differences leads to wider & deeper experiences. We can disagree, but curiosity empathizes. 🎂🎂🎂TAKE MY BIRTHDAY WEEK QUIZ 👇 & SHARE THE CAKE 🎂🎂🎂 🧵 to quiz yourself: