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Someone just shared with me this study."Repellency longevity tests showed a two-week effectiveness against stable flies found from both the coconut fatty acids and lauric acid at an application dosage of 20 mg (1 mg/cm2)"https://t.co/Xhei8ffYaO
"Researchers have found that feeding mosquitoes bacteria inoculates the insects against Plasmodium. And if the mosquitoes can’t carry the malaria parasite, they can’t accidentally pass it on to the humans they bite." https://t.co/0avNp8dlaC
Now that I'm up in Burlington Area, I have noticed that at dusk or in the shade there are lot of big tiger mosquitoes.I don't think I'd be able to do anything to fight infection, but maybe I can stop from being bitten?https://t.co/7XgfISJ1QG
That idea of using components of MCT oil as an alternative to DEET has also rekindled some of my old ideas of feeding skin bacteria.https://t.co/Ypla0IxIl8
The DEET alternative also says the cocoanut oil it has Mystric Acid as a component. One of the things I think the MCT oil I use in my bullet proof coffee is doing is because of that.I know how to make that with a human commensal!https://t.co/JxVt4W0ILA
Even if the Tiger Mosquitos they found in Vermont don't currently have Dengue, the welts they give me are obnoxious. I appear to be hyper allergic to their saliva.https://t.co/2LIv0mrvsE
I've been using this as a DEET free alternative, but it isn't nice to breath during application. Makes me smell good tho. https://t.co/oI5K7KMng9
I wrote a poem lamenting this.https://t.co/aaAU1cAWXp
Mosquito bites annoy you?Maybe go inside.But do they go away?Or find another meal.Waiting for you to come back out?Their time they abide.An answer to mosquito pain?Learn to quickly heal.Mosquitoe bites annoy you?But from them you cannot hide.https://t.co/gs12yegdQ9
I have always been extremely attractive to mosquitoes. They seemed to love the smell of my blood.This is something I've suffered w/ since I can remember. The trauma of having 100s of bites while no one else got any when I was 4yo was a big reason why I hated the outdoors.
The idea of changing the way I smell to them is super fascinating.https://t.co/mKuNrE8Kza
Hmm. Instead I should change my skin microbes?"After completing such a study with Anopheles gambiae, we would then need to test other mosquitoes. You might be surprised to learn that there are no fewer than three thousand species of mosquitoes on Earth"https://t.co/zK851654CV
Something that might be happening is that I may not have a lot of melatonin in my blood? or maybe in a normal 24-hour circadian clock, the melatonin cycle matches up with dusk somehow?Weird idea, but fun to think I can poison them with my blood some how.https://t.co/xLE07DtTV1
Oh, I forgot to talk about why I'm adding this talk about mosquitoes. I found out that we can fuck with mosquitoes by messing with their melatonin signaling. https://t.co/YQ5zVQNm7s which might be acting via the same mechanisms I noted here: https://t.co/3WfDgW2TT7
I noticed during the day the mosquitoes like to hang out around trees and shrubs that look like pine needles. They appear to be staying in areas that have a humid microclimate.When the air is humid and hot, they will come out during daylight hours too.https://t.co/eVWN3yTQRt
I'm really just mad that humming birds in the backyard come to feed at same time that the mosquitoes start to bite. I also realized they are very sensitive to sunlight, atmospheric pressure, and humidity. Got me thinking that it might be happening in bees. https://t.co/RNenZRlskg
GF has been joking the garlic smell from my honey-garlic ferment is repelling her like she's a vampire.Wonder if there is a fermentation thing that repels the tiny flying demons we call mosquitos.https://t.co/ywTeR5Am37
GF: "It smells so bad!!! so stinky!"ME: "I'm sorry I'm not sorry."Note to self, do not use big jars again unless I have a proper nipple lid or water trap. Had to poke a hole in the top of can + make a makeshift seal using some packing tape. I could not open for the life of me.
How to stop this with diet or microbes?"An analysis of chemical signals called cytokines also presented a complex story of pro- and anti-inflammatory activity across the week, one that was hard to explain in terms of a garden variety immune response." https://t.co/whIlOWCF7L
If you have 23andMe, there was a study on mosquito attractive genetics.This link should work if you login first:https://t.co/QqOUxdatRHI wonder how many of these genes just set the stage for gut and skin microbes via immune factors. https://t.co/3gqVyHmw9N
The idea that it is autoimmune falls out of my thinking here."Researchers also found that women were more likely to report getting larger welts and itchier bites. Women also had a greater perceived attractiveness to mosquitoes."https://t.co/D9kPg4nR3whttps://t.co/IH93J9EjJ0
@madalienmilkman I basically ignore gender & look at raw homone. But all the science studies frame it as male/female! its obnoxious."Immune-mediated diseases typically show a female preponderance. Looking at all autoimmune diseases combined, 8 of 10 patients are females"https://t.co/9pptZ0zWAJ
But what is actually going on here?https://t.co/iUerlKoLkJ
@s_r_constantin "the sex bias in MS and other autoimmune diseases may include sex-linked genetic factors, [...] Interestingly, a later onset of disease in male patients compared to female patients coincides with a decline in bioavailable testosterone in men"https://t.co/ZxPgpHlIT8
There is some indication that there are gender hormone related biases in parasitism. But when looked at in birds nestlings, it may actually be about body temperature biasing mosquito bites somehow? https://t.co/10FlUIIKujNot clear if applies to humans.https://t.co/wOH1LwUZmo https://t.co/SnnFgt58XD
Also, you saw read that right, my research in to birds eating their own baby's shit is relevant to mosquito born illness, gender hormones, and auto immune diseases.https://t.co/80Fc36h9YT
Person who sent me that MCT oil thing has been digging a bit. Seems like its not just straight 100% MCT oil, but added a bunch of other chemicals turned into a powder.https://t.co/MmCMdmNfvn https://t.co/GQuo3K8XJS
I found my old notes on trapping and catching mosquitoes to test for diseases. Looks like the account that paid $$$ to advertise that B.S. to me was suspended.https://t.co/pv9O6FHuPU
I bought one of these https://t.co/H1TbxGrSjb to do the same thing. US patent US7832140B2There are YouTube tutorials for making a fan based mosquito catcher out of a screen mesh and fan, its not hard to put 2-and-2 together.https://t.co/YxW5kGS072#actuallyautistic #adnoyance https://t.co/35j7qFAnKb
It appears I do not actually understand what MCT oil is. These chemicals would be found in the oil, not necessarily added in. So I guess I get to try it out tonight and if it works then it probably has the right chemicals here. https://t.co/G52al3KrRT
My current bottle only says "100% MCT oil" and "organic" so I can't tell.I've been using https://t.co/DIPmIK7JsG in my morning coffee cuz its the only one I can find that isn't a powder.
I wonder what color spectrum mosquitoes can see in.https://t.co/kyHTyNdHGR
"Native Americans who burned sweetgrass (Hierochloe odorata) tended to do so for ceremonial purposes. However, some had a more practical use in mind. Two groups [...] used sweetgrass as an insect repellent."https://t.co/1A1z6KlQYyhttps://t.co/326KftY5Z9
This is amazing @treesntreesntre! "Bananas and beer [20,21] are the only dietary components that have been shown to increase mosquito attraction. Digestion of some types of foods appears to result in rapid metabolic changes that alter host odors"https://t.co/NBloy9srf3
Bananas & Beer?"Diet can change human odors but whether specific dietary components alter host attractiveness is largely unexplored. We identified bananas as a target for study following a survey of the internet for advice on avoiding mosquito bites."https://t.co/ewzL0dAn3T
Was speculating about this with @jaycousins a while ago too. https://t.co/j6sathcxr2
Jamie Mantzel discusses lighting *coconut husks* on fire as away to repel "chitras" which he describes as mini mosquitos. (This is in Panama).He does it at 11m22s here:https://t.co/U85Ya01QgPI wonder if there is anything special in the smoke.https://t.co/PIxlgXAZO0
This is a satire article. But *what if* your farts could actually kill mosquitos?https://t.co/RQf8hW2lAQ
This leads to interesting questions about killing mosquito gut bacteria https://t.co/PvffM3TCwp
"put the bacteria into the artificial blood supply she feeds to her mosquito colonies, hoping they would ingest the bacteria and she could track whether the mosquitoes were harmed. But her mosquitoes wouldn't go anywhere near" https://t.co/DSDhxtAbTf https://t.co/vfaGJ9HYSi
Neat idea."Malaria control based on such natural anti-parasitic microbes will likely be easier to gain peoples acceptance and thereby implementation"https://t.co/yfCXDFFZ5Lhttps://t.co/jdw5nXk6fH
Looks like that anti-malaria bacteria could be Wolbachia?https://t.co/ktGkXaRlh9https://t.co/IscW15QCXw
Picrotoxinin for everyone!https://t.co/Z3StHJfhMphttps://t.co/gHU9Jvbt6Y
Did you know you can just call an extremely potent anti-mosquito chemicals a natural fragrance?If you get genetically engineered e-coli to shit it out for you it can even be made efficiently and at scale. https://t.co/hTXlrTdPuCI'm sure it's fine.https://t.co/tEXIYDgV5I
Self-neutralizing gene drive didn't self neutralize."found that some of the genes from the genetically modified mosquitoes had transferred to the native population. In other words, some of the offspring had survived and were strong enough to reproduce." https://t.co/lxZeWRVbH8
I was able to experiment with using MCT oil as a mosquito repellant. Ate some bananas, then was outside shirtless for about 6 hours including dusk, doing laundry. This was after not showering for two days (sleep schedule makes it easy for me to forget). Only got one bite.
Huh."Some mosquitoes specialize on feeding on parts of the body that are difficult to see and difficult to swat. For example, Aedes aegypti is a mosquito species that prefers to feed on humans, mostly around the ankles." https://t.co/G0oZAkrCqi
Flying demons that spread disease. Purify."Citronella, sage and rosemary when burned, repel insects. Herbs with similar effects would certainly have been a benefit to life in a cave or other prehistoric shelter."https://t.co/JJwqkNiBuV
Shifting the gut microbiome of mosquitos makes them susceptible to pathogenic fungus."Our study may lead to new strategies for biological control of mosquitoes." https://t.co/po0SoEZ5l7
"Locally Acquired Malaria Cases Identified in the United States"https://t.co/bkSlrtrqjdhttps://t.co/FTnDt597RP
"About 2,000 cases of malaria are logged in the U.S. each year, according to the agency. The last time mosquito-borne malaria occurred in the U.S. was in 2008, when eight cases were identified in Palm Beach County, Fla."https://t.co/6RZAficvgE
It's weird that we have locally acquired cases 1993, 1994, 1995, 1996, 1998, 1999, 2002, 2003, but nothing until 2023.Do we know why there is a gap? https://t.co/7bjwjY8UMw
"Among the bacterial populations that were different between “resistant” and “susceptible” mice were Lactobacillus and Bifidobacterium, and treatment of mice with Lactobacillus and Bifidobacterium resulted in decreased Plasmodium burden."https://t.co/ljpVUmGmL3
Shame we're going to argue about climate change and not try to figure out if the gut disruption caused by covid may make people more susceptible to plasmodium.https://t.co/dZj5BZtIfA
"A new study published in the American Journal of Tropical Medicine and Hygiene finds that now roughly 1,500 people are hospitalized each year in the U.S. with malaria." https://t.co/84z91mMCOW"We Assume", you say? Seems like a bad thing to do if it's so devastating. https://t.co/0fDloHT2KN
What's really stands out to me is that from 2000 to 2014 it's very much concentrated on the east coast. Could it be that there are pockets of plasmodium being spread intermittently and we just assume these are from travel? https://t.co/MLFxFSLNX5 https://t.co/EYfWpemmSF
We supposedly eradicated malaria in 1950s, but there isn't really much preventing it from coming back.https://t.co/Eq6trceglG
Please don't spray us with gut destroying pesticides and repellents again.https://t.co/5vyEXBOSe0 https://t.co/5soUKef3k5
"One big unanswered question right now is: Why are two geographically distant parts of the US seeing local transmission of malaria right now — especially after so many years without it?" https://t.co/T6R1OMYaII
Did you know what drives Bifidobacterium loss? https://t.co/dtZqlSQuIf
"Friendly bacteria that produce the chemical butyrate, such as Bifidobacterium pseudocatenulatum and F. prausnitzii, were the most likely species to be depleted in people with long COVID 6 months after discharge."https://t.co/rktN9z4tNg
Faecalibacterium prausnitzii is also one that has been noted to be low in people with HIV, which predisposes a risk toward Malaria infection. Suspected to be related to health outcomes thru oxidative stress.https://t.co/MhsyRaiER0 https://t.co/iaLqgvT1qH
Does anyone know why older people get more severe malaria? I have a guess.https://t.co/8ueMKsNNja https://t.co/zH4uDgQEYu
Or young children? I can tell you that I had weird dermatitis for well after my infancy. I wasn't breast fed and prob missing ketose."The F. prausnitzii population in the intestine reaches a level comparable to that in adult at approximately 2 y of age." https://t.co/LZu4rNNCjA
"Mast cell (MC) activation and translocation to the GI during malaria intensifies damage to the physical barrier and weakens the immunological barrier through the release of enzymes and factors that alter the host response to escaped enteric bacteria." https://t.co/2kYSHTa9t0
Atopic dermatitis, in my mast cell activation syndrome driven by poor gut health, potentially enhancing malaria parasite infection strategies, and treatable via F. Prausnitzii (missing in long covid)? Imagine that.https://t.co/IGQY6C1IsT https://t.co/uUdUHEmk8U
I told myself a joke a while back to encode a memory. Cuz I was laughing at SBF.https://t.co/noHDPwHw66
I followed up with a punchline https://t.co/PXdANjiVGr
Telling jokes to make the gods laugh.https://t.co/e3iwuY9cJb
Sure is weird to think about mosquitoes drinking the blood of people with antifungal pharmaceuticals and the impacts it has on their gut health and parasite survival. But someone's gotta do it. https://t.co/erVKadrTW6
Scream at plants until the mosquitoes go away.https://t.co/sEZuXZ879E
That is to say, have you considered growing insect repelling herbal plants and using them to "fumigate" your house using incense?https://t.co/UhBOPVsLfo
Good book on herb gardens.https://t.co/qtT712kHHi
Doesn't everyone study the theory of Doctrine of Signatures and how herbal associations with planets (astrology) took over, and how planets represented healing gods that ended up encoding mechanisms of action in a plant via Ancient Sumerian Gallu and Gula?https://t.co/Cfz5gvS2TQ
Demons are coming.Little flying syringes that bring pestilence and disease. https://t.co/4Khzh5mmMa
If mosquitoes are attracted to individuals who smell of fungus & have a low body temp... Maybe try eating stuff that promotes antifungal compounds. Maybe try having a healthy gut to make immune active SCFAs to feed immune system (which increase body temp).https://t.co/hc6nmM1fnA
Some fermented food can provide both Bifidobacteria and Prausnitzii. https://t.co/Uf1gGFhNGc
They're making the mosquitoes gay.https://t.co/pmSjFLUMq7
In doing so they neglected to check for if they can use bacteria and fungal co-infections to drive parthenogenesis. https://t.co/f08EMJezDI
"Mosquitoes with Wolbachia for reducing numbers of Aedes aegypti mosquitoes"https://t.co/FoI19S9MSGWhat ever could go wrong here?
But but mosquitoes can't self-reproduce if they all female.. right? RIGHT?Well. There is precedent. "Parthenogenesis occurs in the mosquito Culex fatigans." [1959] https://t.co/jUiYAG5HeN
*haha*https://t.co/6dldg7PReB https://t.co/OxjEEoYwDe
"support the ability of Lactobacillus and Bifidobacterium to contribute toward the modulation of Plasmodium parasite burden, yet other constituents of the gut microbiota may also contribute to regulating the severity of malaria"https://t.co/ljpVUmGmL3https://t.co/KSNtgGstTQ
"The knowledge from this exercise will inform innovation possibilities for future tools, technologies, approaches, and policies around the prevention and management of malaria in endemic countries."https://t.co/GpZBKTn893https://t.co/79iPr6lAPp
"Inside a two-story brick building in Medellín, Colombia, scientists work long hours in muggy labs breeding millions and millions of mosquitoes."https://t.co/TqISWvNxsa
Powder keg and spark.https://t.co/1wrHBeS8en
"Despite the studies connecting gut microbiota to the prevention of malaria transmission and severity, research on developing functional foods for the purpose of manipulating the gut microbiota for malaria control is limited" [2021] https://t.co/kA5VNcUF4Bhttps://t.co/LPOaA7tsaP
"Challenges of Developing a Probiotic-Based Vaccine""This probiotic-based vaccine would have low production costs and would be easy to administer to high-risk populations in the poorest regions of the world."https://t.co/yDfyAed95GVile.https://t.co/oqePoDsA1f https://t.co/Jg87aCu3Dd
"Quinine, an old anti-malarial drug in a modern world: role in the treatment of malaria"https://t.co/VXnWPCWi1Nhttps://t.co/Kj8zVQZ7Iu
Do you know your blood type, anon?"These results demonstrated that malaria incidence positively correlates with the frequency of blood type B."https://t.co/xE7287hTYB https://t.co/NNfqAQB7bo
I filled my head with ideas, mixed in some chaos. Fell asleep wanting to dream of Isaac newton, and slept. https://t.co/FF4EMUi0m4
My web of tweets was locked away from me. So I had to use my memory to summon an idea.https://t.co/XstMUIk8b6
I did not dream, but I awoke in a half-awake state of existence of Hypnagogia where I contemplated my ideas. https://t.co/zVh7a2IZNS
I dreamed of a swirling toilet. I awoke thinking about yin and yang, energetics, and disposition. https://t.co/892b7uvh4V
In a twilight haze of slipping in-between conscious and unconscious thought; I asked my self "how do we clean the blood from parasites?" and "what can we do to destroy the parasite in the liver?"https://t.co/YpSVrKdbDL
"a successful example of drug development from natural products, artemisinin and its analogs are presently in wide use for the anti-malaria treatment. This shows how research using natural products has made a significant contribution in drug development" https://t.co/0fry2t2zUu
"might seem unusual about her scientific work is that Tu began by looking to the plants used in traditional Chinese medicine. But it is far from the only time a modern cure has been found from traditional Chinese medicine and it is unlikely to be the last" https://t.co/ik5Mcmq9FH
"discuss how artemisinin and its derivatives could be repurposed to treat cancer, inflammation, immunoregulation-related diseases, and COVID-19. […] implications of the "artemisinin story" and how that can better guide the development of TCM today." https://t.co/e0GFlMoqcw
Datamining ancient wisdom. Literally. Published 5 days ago.I have never seen this before. It came to me in a dream."Analysis of Medication Rules of Traditional Chinese Medicine for Malaria Treatment Based on Data Mining" [June 28 2023]https://t.co/X5I7qK3VK1
"This review aims to overview some TCM theoretical concepts and the evidence-based clinical application of TCM’s leading practices to create an easy-to-consult and condensed source of information, available for the healthcare community" https://t.co/2ZcM61EILv
"Therefore, TCM and Western medicine could share similar philosophical methods to fight COVID-19 and understanding their philosophical theories could achieve the maximum benefits for treatment of COVID-19 and other diseases." https://t.co/GAuHBvnnk5
I know where to seek answers. I just need to learn how to ask the right questions.https://t.co/sHUDDhKC0K
Finally found a set of books that attempts to extrapolate TCM and Ayurveda and connects eastern traditions with more recent western findings on the gut microbiome.Author doesn't have a big web presence, but found a talk https://t.co/9EXNI3tgwqhttps://t.co/uwxXdWCNRO https://t.co/9nIn2tRqI4
The problem has been solved, and forgotten.https://t.co/UiHCts1U1A
I remembered why I said this.https://t.co/PHvk9K1EH5
@SHL0MS @0xfbifemboy "Here, we investigated the genome-wide responses of P. falciparum to DNA damaging agents and provided transcriptional evidence of the existence of the double strand break and excision repair system." https://t.co/ua1WO6NRtWooooh neat. Gonna become a malaria expert now.
Solved and forgotten. Find it.https://t.co/7WlGvFvjq5
Find it, where could it be?Is it under this lamp post? Or lost out to see?https://t.co/OHOJfUC1o7
"Nathan Myhrvold and team's latest inventions -- as brilliant as they are bold -- remind us that the world needs wild creativity to tackle big problems like malaria."https://t.co/yP5CwC7Ha2https://t.co/4fRbElbEkk https://t.co/wb7HAO9DoX
Have you considered exploring parthenogenesis among humans, anon?https://t.co/MuhlsCZBh9
Talking to Claude-2-100k about ancient Sumerians using date palm to as a potential aid to fight malaria, like one does.https://t.co/eb8RxTxeY7I guessed that it would upregulate bifido. https://t.co/eJeKJbo0Ga
"Rich in phenolic contents, dates are known to have antiviral, antibacterial, and antifungal properties, making them a possible source of compounds for the treatment and prevention of infections." https://t.co/F49ZySNlOqWonder if the seeds specifically are antiparasitic.
Maybe not directly anti-parasite(?), but hemolytic potential suggests Date Palm Fruit ('dates') may help if you need to get your body's immune system to kill a lot of red blood cells for reasons.https://t.co/j8EzfH8RyU https://t.co/sEpetIc3C6
I will change our models of history to cure disease. https://t.co/9na1VeaZng
*Furiously googling how to grow catnip*https://t.co/KVXMPVpwzQ
That 'nepetalactone' thing seems antifungal too. I tired catnip tea and it was pretty tasty. Calmed me like other mints. https://t.co/3LbwAUGx5d
I bet it works just as well as a biofilm inhibitor and mouth wash too. I wonder if it works for oral candida / thrush?https://t.co/SFKpULJh8h
"Rubbing behavior transfers nepetalactol onto the faces and heads of respondents where it repels the mosquito, Aedes albopictus. Thus, self-anointing behavior helps to protect cats against mosquito bites."https://t.co/Pl4WqpPpDd🙀😻😽
So. Fucking. Cool.This is my favorite kind of citizen science!https://t.co/LLlR2tz1RX
What if... Fan over door?https://t.co/x0eq124fLe
@ultimape Be careful. https://t.co/Fexm2FYsDe
@CKJReads There's a weird phenomena here.https://t.co/ARCHsQvlw7
@CKJReads "Older adults have a higher risk for dehydration due to lower fluid content in the body, a decreased thirst response, and medications or underlying conditions." https://t.co/knxDINSELvhttps://t.co/Z79meNYSmk