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Amazing study. https://t.co/bKIkxxEC8hAmazing person.https://t.co/Dvmqc43Yj9 https://t.co/QbzwuBpyiz
Please someone tell Dr Carmel Harrington to research gut bacteria's role in choline function."This gives us a focus for our future research. So there's quite a lot to be done. We need to understand the system better " https://t.co/jkS3dWzin7
CO2 sensing in the blood -> wake up reflex to breath.https://t.co/8iw49Y8Mlb
I keep running into SIDs while researching autism/seizures. I suspect hippocampus involvement."Dr. Kinney stressed however, that more research is needed to prove that seizure is the cause of death in many SIDS cases."https://t.co/yoBL5CkuhV
Keto => better mitochondrial funciton => CO2 causes less seizures.Its going to be the same space as the gut bacteria here https://t.co/ebxE4dL6VG
Hippocampus this."Hippocampal monoamine metabolism and the CO2 induced retrograde amnesia gradient in rats [...]"Changes in hippocampal serotonin metabolism parallelled the amnesia gradient."https://t.co/sreLIxOdF1https://t.co/eDSSNaRADw
Sleep Apnea. Dynorphin. Sleep Terrors. Not waking up when can't breath. => Lipid function + Gut bacteria.https://t.co/pQXPHAGRc0
This is how I learned to see the sleep demons and steelmanned lucid dreaming. Fats + Glycine + sugar (cortisol) to destabilize serotonin and melatonin just enough to keep my hippocampus awake.I think this is the same system involved in choline regulation.
Huh."We have proposed that the neurotoxic action of these agents is mediated in part by a complex polysynaptic mechanism involving an interference in GABAergic inhibition resulting in excessive release of acetylcholine (ACh)."https://t.co/4FImkKdH1ahttps://t.co/qlX4q2WHJr
"we reasoned that a combined lesion of 5-HT and GABA parameters in SIDS infants may be particularly deleterious. Virtually nothing is known, however, about the GABAergic system in the brainstem of SIDS infants." [2011] https://t.co/9jzTYiuLae
But more interesting is I suspect my synesthetic experiences are driven by serotonin+gaba+glutamate producing gut bacteria. The kind of chemicals that help boost neuronal firing similar to psilocybin; Reported to give people synesthetic like experiences.https://t.co/24tePxWoVD
Would I?https://t.co/9pZFaLcCCU
My assumptions here: complex regulatory network to modulate immune system response microbial colonies in our gut, driving both anxiety (gaba) and aggression (serotonin) to influence food foraging behavior under varying environmental constraints. https://t.co/lK65nwv35f
Suspect that?https://t.co/QQMR06Auv7
@naval My bet is this is a symptom of low GABA, and cause is actually diet and medicine impacting gut microbes, with oversocialization and overstimulation being a correlation/red-herringI haven't had anxiety for more than a year after figuring this out. YMMVhttps://t.co/HLvXJ6anpG
"protected [...] because of the human blood-brain barrier, but [...] barrier does not fully mature until three-to-six months of age, [...] may be a window of time where small proteins [...] may have access to the infant brain.”https://t.co/hnb99kBsNWhttps://t.co/2ZKWVWUs4M
How is gut signaling the brain re:gaba? Can brain make gaba locally? Why does gaba play a role in intestinal problems. Why does blood brain barrier seem to coincide with intestinal permeability. Why do I have genes that predispose for BBB permeability?https://t.co/6yHLo6NXkH https://t.co/hMlcRg50b6
Gut poverty."SIDS mostly affects the poor in prosperous countries [19–21] in whom infectious diseases are also relatively more common." https://t.co/3uQtoCP4PF
Gut & Barrier function problems, driving a psudohibernation tied to immune function."We conclude that S. aureus fits the mathematical model for SIDS. Both staphylococci and/or their toxins were identified in a significant proportion of SIDS cases." https://t.co/YsYSjM2XDp
SIDs => CytokinesCytokines => DynorphinDynorphin => CO2 problems.The system that lets me see demons in my dreams.Can't wake up while that happens.https://t.co/rm2mnIYxGY
I find this weird trend where sleep paralysis combines shadowy figures and sensation of things on your chest. If you are having trouble breathing because of a weird cytokine phenomena disrupting dynorphin signaling, it could explain it.Visceral Hallucinations can feel like sex. https://t.co/qasR0Th3UR
"The serum ischemia-modified albumin levels were significantly higher and the butyrylcholinesterase activity was significantly lower in patients with obstructive sleep apnea than in the controls (p<0.001)."https://t.co/ujwTHPVouH
I liked when @rivatez interviewed alex jones.https://t.co/kJx7OferTx
He's talking about people tripping while sleeping due to sleep apnea and other breathing problems, and further reinterpreting as the sensation of talking with aliens? Alex has been researching his own etiology. I bet he has those experiences as he says. https://t.co/4QS0M2yor9
Its the same picture.https://t.co/f1SQlDNuxP
@rivatez I suspect ties we're seeing between oral microbiome and blood pressure are also within the same functional network as sleep apnea too.https://t.co/0TQIxpyTUoLots of studies on that oral nitrate bacteria seem to match up with what CPAP machines do there.https://t.co/b1n20zwT8K
Wake up.https://t.co/0K0VwlVpT7
There's something complex going on w/ how my body responds to stress and CO2 that is triggering dynorphin, but happens during sleep apnea, and would be mimicked by immune activation/cytokine's action on dynorphin receptors.https://t.co/rRsAVsvu2yhttps://t.co/7VL9gDYd5j
Demons will come and suck out your breath.https://t.co/9gNqHJrNto
The demon inside of a cat. T gondii.https://t.co/OuudKu1RSB
Thiamine Metabolism linked to sleep apnea"very likely that many of the poorly understood symptomatology seen today that responds to nutrient therapy is caused by a mixture of marginal classic nutritional diseases, including beriberi, pellagra and scurvy."https://t.co/z3hWW7rvvJ
Demon as early medical model of disease.https://t.co/TM1WR1JZm5
"dates back about 300 years to when cats were associated with witches. [...] sometimes blamed for smothering babies in their sleep. Of course, there is no truth to this myth. Those sudden deaths were probably due to sudden infant death syndrome (SIDS)" https://t.co/ZsFoVlwoSZ
How far back does framing Jews as witches and drawing them as cats date Surely anitsemitism and cat murdering started well before the 1700s? https://t.co/564pdET3Al
Thinking to myself about how funny these things are and how it's harmless tomfoolery in medieval manuscripts. Turns out it's probably hateful derogatory memes being spread by the ruling ideology, possibly associated with traditions tied to Ailuromancy. https://t.co/fpv2SoPX9m
All my gut problems that would predispose me to getting candida and t gondii infections are the roughly 3% of my genes rooted in the same lineage as Einstein.https://t.co/4sQ65ljcGF
Children are dying because your model of the world is wrong.You blame parents as scapegoats and shame them for their behavior. Call them a baby murderer.You are the monster.https://t.co/3I2Eylac23
I am not wanted here? At least not by the powers that be. I am the dreaded [meta-outgroup], both the [ingroup] & [outgroup] see me as an enemy.[Burn] the [witch] and kill the [changeling][stop] the [demon] and kill the [spawn][end] the [person] and kill their [words]
What could he mean by this?" We propose that Toxoplasma acts as a trigger setting into motion a series of events culminating in loss of tolerance in the intestine and emergence of pathogenic T cell effectors."https://t.co/2Ew44XwRGehttps://t.co/zzQluA0z8U
oof."The aim of this review is to summarize recent novel findings regarding the possible association of beta-casomorphin (beta-CM) to apnea in SIDS, which has not been widely appreciated by pediatricians and scientists." https://t.co/oUEX8KPq8Chttps://t.co/bOxR1LWgyd
"To be, or not to be: that is the question:Whether 'tis nobler in the mind to sufferThe slings and arrows of outrageous fortune,Or to take arms against a sea of troubles,And by opposing end them?" — Hamlet, Act III, Scene I, by William Shakespeare https://t.co/txb6o6HpjL
Death and resurrection.Evidence based medicine once said the dead can't come back to life.Se we redefined death.https://t.co/kPyphbIiIU
"While exploring suspended animation in mice, scientists discover how an enzyme can protect the brain from dangerously low levels of oxygen."https://t.co/2zdS2KNOKj
I'd have called it coyote pee.“We presume death is a thing, it is a state of being,” she said. “Are there forms of death that are reversible? Or not?”https://t.co/tk1FwcKIy9https://t.co/2Spbj1LQiN
Steven Spit.YOU HAVE ANGERED THE GODShttps://t.co/8VUUX7khj0https://t.co/g5BOYpSi0N
@Maxiimiliano_L @DavidRCrowe Do we have a answer for what causes SIDS yet?"We propose a new hypothesis that the infant gut microbiome plays an important role in SIDS during the period critical to both gut flora aturation/development and vulnerability to SIDS" https://t.co/s2VoWeteyJ
Chaserhttps://t.co/DQim8rzQWv
@ricyoutube @GRITCULT Yeah, its bad. Implies that formula feeding isn't providing de novo synthesis. It seems in infants with higher risk of death thru hypoxia, their body tries to make more creatine phosphokinase to compensate (but presumably can't use it to make creatine) https://t.co/nT8Tf6shT0
> "Breastfeeding is protective against SIDS, and this effect is stronger when breastfeeding is exclusive." https://t.co/WYoZolMcCF
They're still looking at correlations btw autism and SIDs by measuring supine sleeping. So fucking dumb.> "Hypothesis on supine sleep, sudden infant death syndrome reduction and association with increasing autism incidence"https://t.co/6Km8WjN0eJhttps://t.co/gIkk0CT2gJ
@SSavson Fixing autism is my autistic obsession. I found it curious that older male sperm seems to be a risk at causing autism in the child. I think its due to dna damage problems tied directly to lack of phosphocreatine in the seminal fluid.https://t.co/n7q8s4u8Ay
We probably overlook this aspect in SIDs because the use of it would be transient and not show up meaningfully in assays.https://t.co/fRQvYt1Og9