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🧵 Thread (15 tweets)
"Coronavirus disease 2019 (COVID-19) can therefore severely affect myocardium with life-threatening complications and even young people can be involved." https://t.co/ziFel9PowG
"the present study indicates that ACE I/D and rs4343 polymorphisms can be a risk factor associated with autism and this highlights the role of RAS in this illness. However, further genetic studies in various ethnicities and populations are warranted."https://t.co/DrVdQETxcd
"We found that G allele of rs4341 and rs4343 was associated with severe COVID-19 in hypertensive patients, independently of gender (p<0.05)" https://t.co/BtcAxEWaXf
Do elite athletes seem to get hit with covid related heart problems harder? We'd expect this if ACE mutations are more common.https://t.co/Z73IbqvGrN https://t.co/Wz1aQq16Vv
Good, someone's looking into it."Now with COVID and its potential impact on the heart, it’s more important than ever to understand whether athletes face unique risks or greater protections based on their cardiovascular features." https://t.co/9QnZYfGexJ
rs4341https://t.co/bFwyasmJMgrs4343https://t.co/orJ9ZmGA1c(23andMe are not useful for medical diagnosis quality information)
Why does a blood pressure medication (betablocker) sometimes help autism?https://t.co/p243cSJdJl
There's a 2013 medical hypothesis that anti-social behavior may be driven by ACE pathways among schizophrenia and autism.https://t.co/XXhDH36nQ1 https://t.co/CW43R7fUtg
Not on autism"further support for the angiotensin system as a novel therapy target, and that drugs that decrease activity of angiotensin, specifically ACE inhibitor and AT1R blockers drugs, can lead to benefits from a psychiatric perspective" [2018] https://t.co/GaQIdhFWCO
I can't find anything specifically on autism, but "Renin-angiotensin system promotes colonic inflammation by inducing TH17 activation via JAK2/STAT pathway" https://t.co/n7AdPNvCSx
This might explain why hypertension in mothers can lead to higer riks of autism. If JAK2/STAT3 is being hit thru cytokine and angiotensin... well... lets just say that impacts another group of people who have inordinately increased bad outcomes.https://t.co/TMjt5hymLg https://t.co/OqnGMT6xA4
Two groups of people with higher rates of problems associated with heart complications from Covid...Autism and Alzheimer's.The question is, how much of this is from living situation (group home), and how much is biological underpinning? https://t.co/lAJqBNMrRf
Bark woof bark.Cornus officinalis"Japanese cornel dogwood"Action against diabetic nephropathy via ACE, JAK2, MAPK 12.https://t.co/M4VBanwisDhttps://t.co/YdT7kuOq5o https://t.co/LhtqqlqU0r
Epiphanyasd here again. Running down the same paths I am, but independently.https://t.co/eablRIJn4O
Yep, just arbitrarily fingering a traditional Chinese medical herb at the intersect of eastern and western medicine by inferring action via a known genetic risk factor.https://t.co/ENwDGoK6frJust another day on twitterdotcom