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Watching this. Heard that placebo sugar pills treat ulcers.https://t.co/dL84zByv8x
If placebo is oxytocin driven, then maybe the ulcers where healed because of impacts of trust and safety effects?https://t.co/oQdb56c0yz
ok, but that doesn't explain the pain removal effects.https://t.co/ykBttsnJoi
But it might have secondary impacts on a chemical that has been shown to reduce pain. https://t.co/uR96RCuM0s
And we also have account for chronic vs acute pain. With chronic pain being driven by immune system in some cases.https://t.co/1MjiGAsk2R
If I'm right about autism severity being driven by lipid signaling and immune function via impacts on oxytocin (via gut-brain pathway) and anandamide/serotonin production/signaling... I necessarily butt heads with placebo research.https://t.co/dRQCwc68qg
I keep getting these ideas.https://t.co/OvBxqPRiKo
"Future studies should focus on how oxytocin might influence placebo effects, taken into account the role of sex, dose-dependent effects, and various expectation manipulations."https://t.co/puh42yBPnH
If placebo can be enhanced by 'trust' (wearing a lab coat), and MDMA seems to do weird things to trust and risk in a social enviroinment. https://t.co/YiHoAloPIz then does MDMA increase placebo effect? How would you test this WHILE accounting for placebo effects?
I keep finding dumb-ass shit, like this study on MDMA's impact on PTSD that is using Niacin as a placebo.https://t.co/z8QQOoYpmg
If niacin can induce NAD+, and SIRT1 is "NAD+-dependent deacetylase" is on a pathway direclty impacting serotonin and anxiety....https://t.co/CskztolTthWHY WOULD YOU USE THAT AS A PLACEBO FOR PTSD?
Idiots.> Niacin is an efficient NAD+ booster in humanshttps://t.co/CP7b0D1o7w
I bet they don't even control for oxidative stress associated with aging. https://t.co/ntkpZvrVbU
Which also impacts NAD+ efficiency https://t.co/26jHn6FuTq
Another way oxytocin can impact pain is by affecting TRPV1 sensitivity.https://t.co/x00MGwHP8k
Which is fascinating, because so does anandamide.https://t.co/PyduMKCCav