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Saw they found some fun findings around Huntington's Disease with gut bacteria as a potential medication target.It's fascinating.I have been trying to link gut bacteria to COX-2 Enzymes ala https://t.co/NlF66OZffb
chronic stress different response from acute stress."rats, chronic, intermittent water-avoidance stress was associated with reciprocal changes in levels of 2-AG and anandamide (increased) and endocannabinoid degradation enzymes COX2 and FAAH (decreased)"https://t.co/kM3jHl37xI
There's something weird going on."Effects of chronic stress on the onset and progression of Huntington's disease in transgenic mice"https://t.co/RVkcQbZzJ0https://t.co/SSlMq8sjQR
I've never looked at Huntington's Disease before, except noted it was on a list of diseases that might be impacted by Covid-19."Interleukin-6 deficiency exacerbates Huntington’s disease model phenotypes"https://t.co/4pSFgc1M9thttps://t.co/OP40LeDFxl
"More recently, increased microglial activation in somatosensory cortex (as evaluated through 11C-PK11195 binding) was associated with higher plasma levels of IL-1β, IL-6, IL-8, and TNF-α in premanifest HD gene carriers"https://t.co/ZBdJjkikvMHuh.https://t.co/8bPlpd6avb
"This review focuses on the TNF-α system, although other cytokines do also contribute to the interaction between the brain and the immune system and, in part, amplify the effects of TNF-α."https://t.co/ZqZkHoShzrhttps://t.co/eEUCqHZdTC https://t.co/kg65bxLvjA
"The U.S. Drug Enforcement Administration (DEA) cleared MMJ to import the compounds from Canada, after the company made the request three months ago." https://t.co/3lMDWRXjU1I have no idea why... /s
Rats everywhere."Chronic treatment with the selective COX-2 inhibitors significantly restored the mitochondrial enzyme complex activities as well as attenuated TNF-α, IL-6 and caspase-3 levels as compared to the quinolinic acid treated group."https://t.co/kvBzAczypq
Have you tried THC in lipids?https://t.co/KsDO0Y0pznhttps://t.co/NqwSUhTpGa