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...and that is the story about why I started learning about MAPK pathways.https://t.co/ken7qvU58D
I have a suspicion that part of the way our body is able to maintain it's microbiome is thru chemosensing thru the entire tract and I first need to show that the receptors change in a coordinated fashion. 1/2https://t.co/xTgRLNrKrm
Mostly I want an excuse to try doing suppository double blinds for future research into Crohn's disease, while also exploring ways to see if Dysgeusia isn't limited to the mouth.https://t.co/3kSV2oZPvf
Dysgeusia is fascinating. Why do taste sensors seem to show up in parts of the body that deal w/ chemical concentrations, microbial management, or have a high need to maintain homeostatic / immune responses?We have taste receptors in our brain, ovaries/testes, pancreas, & anus.
Does anybody know if an alternate measure of Scoville units exist for judging the 'spicyness' of peppers rectally?If not, can I call it the 'Perry Scale'? I think there may be use for measuring relative pain shifts over time by judging TRPV1 response against a known quantity.
Weird idea: Using the Perry Scale to spread awareness about Anandamide(/THC) and TRPV1's impact on pain sensitivity, mucus, and inflammation problems associated w/ Crohn's Disease.https://t.co/bMDqLyVy7P
"Cleanliness is next to godliness." 😛 https://t.co/8kSDhPIA04
Hey, @steveo! Is it possible to get a version of this hotsauce without all the acids & lime juice? I unironically wanna turn it into a suppository.https://t.co/HFyhvRtY1E
Thank you @NileRed2 for your wonderful instructional videos.https://t.co/SOnkYvJICq
I also wanted to know if vaginal mucus seems to impact any burning sensations from TRPV1 due to a side interest in Sjogren's Syndrome. It turns out that space of ideas is more interesting than I thought.This is amazing.https://t.co/5jamMtFI75
I'm having a lot of fun with this idea. https://t.co/csPdORnfTc
I'm thinking about how to suspend capsacin in a suppository and then I remembered about eggs.Hey are there any other non mechanical ways to emulsify an oil besides egg? I'd rather avoid it because it is F*ck'n raw! https://t.co/LCahssaoDwhttps://t.co/lcYcUIPPOm
Freudian butt pucker using hotsauce.https://t.co/LaB4o90457
Disclaimer: Do not stick hot-sauce up your butt.I am just some autistic guy obsessed with figuring out pain so I can help my mom not be in pain all the time.https://t.co/6jRxkrvzsS
Seems like it may be possible to filter out + evaporate off the vinegar from hotsauce while still having most of the active ingredient intact.I need a good food dehydrator. I wonder if a high end air fryer+toaster oven combo would work.https://t.co/2Tkvkl2Uo3
In other news, I found a source of CBG so I can continue doing my experiments with sticking hotsauce up my butt, and thanks to @rhettmc, @LinkNeal, @mikemchargue I now have a method to test long term capsaicin in my "mouth". https://t.co/qnbB7AqmD2 https://t.co/tSXp5yE1wp
With a good air fryer you can ensure that you aren't destroying the omega-3s within salmon while still getting it to temperature needed to destroy parasites.https://t.co/jIk1rUa7zW